PMC Articles for MedGen (Select 1669222) - PMC

Select item 102993361.

Identification of NRF2 Activation as a Prognostic Biomarker in T-Cell Acute Lymphoblastic Leukaemia

María Villa-Morales, Laura Pérez-Gómez, Eduardo Pérez-Gómez, Pilar López-Nieva, Pablo Fernández-Navarro, Javier Santos

Int J Mol Sci. 2023 Jun; 24(12): 10350. Published online 2023 Jun 19. doi: 10.3390/ijms241210350

PMCID:: PMC10299336

Select item 98338432.

Recurrent transcriptional responses in AML and MDS patients treated with decitabine

Pawan Upadhyay, Jeremy Beales, Nakul M. Shah, Agata Gruszczynska, Christopher A. Miller, Allegra A. Petti, Sai Mukund Ramakrishnan, Daniel C. Link, Timothy J. Ley, John S. Welch

Exp Hematol. Author manuscript; available in PMC 2023 Jan 11.

Published in final edited form as: Exp Hematol. 2022 Jul; 111: 50–65. Published online 2022 Apr 13. doi: 10.1016/j.exphem.2022.04.002

PMCID:: PMC9833843

Abstract Article PDF–3.5M

Select item 82574963.

Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice

Paolo Sportoletti, Daniele Sorcini, Anna G. Guzman, Jaime M. Reyes, Arianna Stella, Andrea Marra, Sara Sartori, Lorenzo Brunetti, Roberta Rossi, Beatrice Del Papa, Francesco Maria Adamo, Giulia Pianigiani, Camilla Betti, Annarita Scialdone, Valerio Guarente, Giulio Spinozzi, Valentina Tini, Maria Paola Martelli, Margaret A. Goodell, Brunangelo Falini

Leukemia. 2021; 35(7): 1949–1963. Published online 2020 Nov 6. doi: 10.1038/s41375-020-01075-3

PMCID:: PMC8257496

Abstract Article PDF–2.4M

Select item 72933104.

Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia

Katharina Leonards, Marwa Almosailleakh, Samantha Tauchmann, Frederik Otzen Bagger, Cécile Thirant, Sabine Juge, Thomas Bock, Hélène Méreau, Matheus F. Bezerra, Alexandar Tzankov, Robert Ivanek, Régine Losson, Antoine H. F. M. Peters, Thomas Mercher, Juerg Schwaller

Nat Commun. 2020; 11: 2807. Published online 2020 Jun 12. doi: 10.1038/s41467-020-16179-8

PMCID:: PMC7293310

Abstract Article PDF–4.4M

Select item 68499355.

Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern

Gerbrig Berger, Mylene Gerritsen, Guoqiang Yi, Theresia N. Koorenhof-Scheele, Leonie I. Kroeze, Marian Stevens-Kroef, Kenichi Yoshida, Yuichi Shiraishi, Eva van den Berg, Hein Schepers, Geert Huls, André B. Mulder, Seishi Ogawa, Joost H. A. Martens, Joop H. Jansen, Edo Vellenga

Blood Adv. 2019 Oct 22; 3(20): 3111–3122. Published online 2019 Oct 22. doi: 10.1182/bloodadvances.2019000518

PMCID:: PMC6849935

Abstract Article PDF–1.4M

Select item 68281606.

Genomic Subtyping and Therapeutic Targeting of Acute Erythroleukemia

Ilaria Iacobucci, Ji Wen, Manja Meggendorfer, John K. Choi, Lei Shi, Stanley B. Pounds, Catherine L. Carmichael, Katherine E. Masih, Sarah M. Morris, R. Coleman Lindsley, Laura J. Janke, Thomas B. Alexander, Guangchun Song, Chunxu Qu, Yongjin Li, Debbie Payne-Turner, Daisuke Tomizawa, Nobutaka Kiyokawa, Marcus Valentine, Virginia Valentine, Giuseppe Basso, Franco Locatelli, Eric J. Enemark, Shirley K. Y. Kham, Allen E. J. Yeoh, Xiaotu Ma, Xin Zhou, Edgar Sioson, Michael Rusch, Rhonda E. Ries, Elliot Stieglitz, Stephen P. Hunger, Andrew H. Wei, L Bik To, Ian D. Lewis, Richard J. D’Andrea, Benjamin T. Kile, Anna L. Brown, Hamish S. Scott, Christopher N. Hahn, Paula Marlton, Deqing Pei, Cheng Cheng, Mignon L. Loh, Benjamin L. Ebert, Soheil Meshinchi, Torsten Haferlach, Charles G. Mullighan

Nat Genet. Author manuscript; available in PMC 2019 Nov 4.

Published in final edited form as: Nat Genet. 2019 Apr; 51(4): 694–704. Published online 2019 Mar 29. doi: 10.1038/s41588-019-0375-1

PMCID:: PMC6828160

Abstract Article PDF–1.8M

Select item 62693067.

ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion

Vikas Madan, Lin Han, Norimichi Hattori, Weoi Woon Teoh, Anand Mayakonda, Qiao-Yang Sun, Ling-Wen Ding, Hazimah Binte Mohd Nordin, Su Lin Lim, Pavithra Shyamsunder, Pushkar Dakle, Janani Sundaresan, Ngan B. Doan, Masashi Sanada, Aiko Sato-Otsubo, Manja Meggendorfer, Henry Yang, Jonathan W. Said, Seishi Ogawa, Torsten Haferlach, Der-Cherng Liang, Lee-Yung Shih, Tsuyoshi Nakamaki, Q. Tian Wang, H. Phillip Koeffler

Haematologica. 2018 Dec; 103(12): 1980–1990. Prepublished online 2018 Aug 9. doi: 10.3324/haematol.2018.189928

PMCID:: PMC6269306

Abstract Article PDF–2.1M

Select item 58654248.

Association of mutations with morphological dysplasia in de novo acute myeloid leukemia without 2016 WHO Classification-defined cytogenetic abnormalities

Olga K. Weinberg, Christopher J. Gibson, Traci M. Blonquist, Donna Neuberg, Olga Pozdnyakova, Frank Kuo, Benjamin L. Ebert, Robert P. Hasserjian

Haematologica. 2018 Apr; 103(4): 626–633. Prepublished online 2018 Jan 11. doi: 10.3324/haematol.2017.181842

PMCID:: PMC5865424

Abstract Article PDF–1.2M

Select item 55993269.

VL Ha, A Luong, F Li, D Casero, J Malvar, YM Kim, R Bhatia, GM Crooks, C Parekh

Leukemia. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Leukemia. 2017 Nov; 31(11): 2503–2514. Published online 2017 Feb 24. doi: 10.1038/leu.2017.70

PMCID:: PMC5599326

Abstract Article PDF–1.0M

Select item 539497510.

CEBPA–double-mutated acute myeloid leukemia displays a unique phenotypic profile: a reliable screening method and insight into biological features

Francesco Mannelli, Vanessa Ponziani, Sara Bencini, Maria Ida Bonetti, Matteo Benelli, Ilaria Cutini, Giacomo Gianfaldoni, Barbara Scappini, Fabiana Pancani, Matteo Piccini, Tommaso Rondelli, Roberto Caporale, Anna Maria Grazia Gelli, Benedetta Peruzzi, Marco Chiarini, Erika Borlenghi, Orietta Spinelli, Damiano Giupponi, Pamela Zanghì, Renato Bassan, Alessandro Rambaldi, Giuseppe Rossi, Alberto Bosi

Haematologica. 2017 Mar; 102(3): 529–540. Prepublished online 2016 Nov 8. doi: 10.3324/haematol.2016.151910

PMCID:: PMC5394975

Abstract Article PDF–3.6M

Select item 365897111.

Quantitative threefold allele-specific PCR (QuanTAS-PCR) for highly sensitive JAK2 V617F mutant allele detection

Giada V Zapparoli, Robert N Jorissen, Chelsee A Hewitt, Michelle McBean, David A Westerman, Alexander Dobrovic

BMC Cancer. 2013; 13: 206. Published online 2013 Apr 24. doi: 10.1186/1471-2407-13-206

PMCID:: PMC3658971

Abstract Article PDF–1.3M

Select item 346618212.

Spi-1, Fli-1 and Fli-3 (miR-17-92) Oncogenes Contribute to a Single Oncogenic Network Controlling Cell Proliferation in Friend Erythroleukemia

Samer Kayali, Guillaume Giraud, François Morlé, Boris Guyot

PLoS One. 2012; 7(10): e46799. Published online 2012 Oct 8. doi: 10.1371/journal.pone.0046799

PMCID:: PMC3466182

Abstract Article PDF–964K

Select item 268204713.

Spi-1 and Fli-1 Directly Activate Common Target Genes Involved in Ribosome Biogenesis in Friend Erythroleukemic Cells

Gaëtan Juban, Guillaume Giraud, Boris Guyot, Stéphane Belin, Jean-Jacques Diaz, Joëlle Starck, Christel Guillouf, Françoise Moreau-Gachelin, François Morlé

Mol Cell Biol. 2009 May; 29(10): 2852–2864. Published online 2009 Mar 16. doi: 10.1128/MCB.01435-08

PMCID:: PMC2682047

Abstract Article PDF–1.1M

Select item 120269214.

Persistence or Rapid Generation of DNA Length Polymorphism at the Zeta-Globin Locus of Humans

Barbara S. Chapman, Karen A. Vincent, Allan C. Wilson

Genetics. 1986 Jan; 112(1): 79–92. doi: 10.1093/genetics/112.1.79

PMCID:: PMC1202692

Summary PDF–1.5M

Select item 20759115.

Identification of a TAL1 Target Gene Reveals a Positive Role for the LIM Domain-Binding Protein Ldb1 in Erythroid Gene Expression and Differentiation

Zhixiong Xu, Suming Huang, Long-Sheng Chang, Alan D. Agulnick, Stephen J. Brandt

Mol Cell Biol. 2003 Nov; 23(21): 7585–7599. doi: 10.1128/MCB.23.21.7585-7599.2003

PMCID:: PMC207591

Abstract Article PDF–646K

Select item 688090216.

The ParaHox gene Cdx4 induces acute erythroid leukemia in mice

Silvia Thoene, Tamoghna Mandal, Naidu M. Vegi, Leticia Quintanilla-Martinez, Reinhild Rösler, Sebastian Wiese, Klaus H. Metzeler, Tobias Herold, Torsten Haferlach, Konstanze Döhner, Hartmut Döhner, Luisa Schwarzmüller, Ursula Klingmüller, Christian Buske, Vijay P. S. Rawat, Michaela Feuring-Buske

Blood Adv. 2019 Nov 26; 3(22): 3729–3739. Published online 2019 Nov 26. doi: 10.1182/bloodadvances.2019000761

PMCID:: PMC6880902

Abstract Article PDF–1.7M

Select item 584671617.

Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease

Sriram Krishnamoorthy, Betty Pace, Dipti Gupta, Sarah Sturtevant, Biaoru Li, Levi Makala, Julia Brittain, Nancy Moore, Benjamin F. Vieira, Timothy Thullen, Ivan Stone, Huo Li, William E. Hobbs, David R. Light

JCI Insight. 2017 Oct 19; 2(20): e96409. Published online 2017 Oct 19. doi: 10.1172/jci.insight.96409

PMCID:: PMC5846716

Abstract Article PDF–1.9M

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