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Select item 111510451.

Dual Activity of Type III PI3K Kinase Vps34 is Critical for NK Cell Development and Senescence

Shasha Chen, Zehua Li, Jin Feng, Yuhe Quan, Junming He, Jiqing Hao, Zhongjun Dong

Adv Sci (Weinh) 2024 Jun; 11(21): 2309315. Published online 2024 Mar 27. doi: 10.1002/advs.202309315

PMCID:: PMC11151045

Abstract Article PDF–8.3M

Select item 108734372.

Enrichment of Immune Dysregulation Disorders in Adult Patients with Human Inborn Errors of Immunity

Alejandro Segura-Tudela, Marta López-Nevado, Celia Nieto-López, Sandra García-Jiménez, María J. Díaz-Madroñero, Ángeles Delgado, Oscar Cabrera-Marante, Daniel Pleguezuelo, Pablo Morales, Estela Paz-Artal, Jorge Gil-Niño, Francisco M. Marco, Cristina Serrano, Luis I. González-Granado, Juan F. Quesada-Espinosa, Luis M. Allende

J Clin Immunol. 2024; 44(3): 61. Published online 2024 Feb 16. doi: 10.1007/s10875-024-01664-2

PMCID:: PMC10873437

Abstract Article PDF–899K

Select item 108219863.

Systematic review of mortality and survival rates for APDS

Jennifer Hanson, Penelope E. Bonnen

Clin Exp Med. 2024; 24(1): 17. Published online 2024 Jan 27. doi: 10.1007/s10238-023-01259-y

PMCID:: PMC10821986

Abstract Article PDF–687K

Select item 101577444.

Transcription factor TOX maintains the expression of Mst1 in controlling the early mouse NK cell development

Liang Luo, Peiran Feng, Quanli Yang, Wenkai Lv, Wanqing Meng, Zhinan Yin, Zhizhong Li, Guodong Sun, Zhongjun Dong, Meixiang Yang

Theranostics. 2023; 13(7): 2072–2087. Published online 2023 Mar 27. doi: 10.7150/thno.81198

PMCID:: PMC10157744

Abstract Article PDF–8.0M

Select item 86695595.

Tcf1 Sustains the Expression of Multiple Regulators in Promoting Early Natural Killer Cell Development

Juanjuan Liu, Zhao Wang, Shanshan Hao, Fang Wang, Yingpeng Yao, Yajiao Zhang, Yanyi Zhao, Wenhui Guo, Guotao Yu, Xiaohan Ma, Jingjing Liu, Feng Chen, Shunzong Yuan, Youmin Kang, Shuyang Yu

Front Immunol. 2021; 12: 791220. Published online 2021 Nov 30. doi: 10.3389/fimmu.2021.791220

PMCID:: PMC8669559

Abstract Article PDF–12M

Select item 86323146.

CD122-targeted interleukin-2 and αPD-L1 treat bladder cancer and melanoma via distinct mechanisms, including CD122-driven natural killer cell maturation

Ryan M Reyes, Chenghao Zhang, Yilun Deng, Niannian Ji, Neelam Mukherjee, Alvaro S Padron, Curtis A Clark, Robert S Svatek, Tyler J Curiel

Oncoimmunology. 2021; 10(1): 2006529. Published online 2021 Nov 22. doi: 10.1080/2162402X.2021.2006529

PMCID:: PMC8632314

Abstract Article PDF–2.1M

Select item 84427367.

SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity

Tao Yue, Xiaoming Zhan, Duanwu Zhang, Ruchi Jain, Kuan-wen Wang, Jin Huk Choi, Takuma Misawa, Lijing Su, Jiexia Quan, Sara Hildebrand, Darui Xu, Xiaohong Li, Emre Turer, Lei Sun, Eva Marie Y. Moresco, Bruce Beutler

Science. Author manuscript; available in PMC 2021 Nov 14.

Published in final edited form as: Science. 2021 May 14; 372(6543): eaba4220. doi: 10.1126/science.aba4220

PMCID:: PMC8442736

Abstract Article PDF–2.2M

Select item 84298208.

Novel Discoveries in Immune Dysregulation in Inborn Errors of Immunity

Anwen Ren, Wei Yin, Heather Miller, Lisa S. Westerberg, Fabio Candotti, Chan-Sik Park, Pamela Lee, Quan Gong, Yan Chen, Chaohong Liu

Front Immunol. 2021; 12: 725587. Published online 2021 Aug 27. doi: 10.3389/fimmu.2021.725587

PMCID:: PMC8429820

Abstract Article PDF–467K

Select item 82136959.

Genome-wide association study identifies five risk loci for pernicious anemia

Triin Laisk, Maarja Lepamets, Mariann Koel, Erik Abner, Estonian Biobank Research Team, Reedik Mägi

Nat Commun. 2021; 12: 3761. Published online 2021 Jun 18. doi: 10.1038/s41467-021-24051-6

PMCID:: PMC8213695

Abstract Article PDF–2.0M

Select item 775403210.

Chronic shift‐lag promotes NK cell ageing and impairs immunosurveillance in mice by decreasing the expression of CD122

Xiaokang Zeng, Caiying Liang, Jie Yao

J Cell Mol Med. 2020 Dec; 24(24): 14583–14595. Published online 2020 Nov 13. doi: 10.1111/jcmm.16088

PMCID:: PMC7754032

Abstract Article PDF–2.1M

Select item 741645811.

Overcoming genetically-based resistance mechanisms to PD-1 blockade

Davis Y. Torrejon, Gabriel Abril-Rodriguez, Ameya S. Champhekar, Jennifer Tsoi, Katie M. Campbell, Anusha Kalbasi, Giulia Parisi, Jesse M. Zarestsky, Angel Garcia-Diaz, Cristina Puig-Saus, Gardenia Cheung-Lau, Thomas Wohlwender, Paige Krystofinski, Agustin Vega-Crespo, Christopher M. Lee, Pau Mascaro, Catherine S. Grasso, Beata Berent-Maoz, Begoña Comin-Anduix, Siwen Hu-Lieskovan, Antoni Ribas

Cancer Discov. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Cancer Discov. 2020 Aug; 10(8): 1140–1157. Published online 2020 May 28. doi: 10.1158/2159-8290.CD-19-1409

PMCID:: PMC7416458

Abstract Article PDF–3.2M

Select item 729445712.

VEGFR inhibitors upregulate CXCR4 in VEGF receptor-expressing glioblastoma in a TGFβR signaling-dependent manner

Kien Pham, Defang Luo, Dietmar W. Siemann, Brian K. Law, Brent A. Reynolds, Parvinder Hothi, Gregory Foltz, Jeffrey K. Harrison

Cancer Lett. Author manuscript; available in PMC 2020 Jun 15.

Published in final edited form as: Cancer Lett. 2015 Apr 28; 360(1): 60–67. Published online 2015 Feb 9. doi: 10.1016/j.canlet.2015.02.005

PMCID:: PMC7294457

Abstract Article PDF–1.8M

Select item 674812813.

Stage-specific requirement of kinase PDK1 for NK cells development and activation

Junming He, Yuande Wang, Tian Liu, Guangao Liu, Shasha Chen, Qiaozhen Li, Yuhe Quan, Haoyan Yang, Jin Feng, Song Wang, Meixiang Yang, Zhongjun Dong

Cell Death Differ. 2019 Oct; 26(10): 1918–1928. Published online 2019 Jan 8. doi: 10.1038/s41418-018-0263-8

PMCID:: PMC6748128

Abstract Article PDF–2.6M

Select item 674333314.

Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis

Kalyani Pyaram, Ajay Kumar, Yeung-Hyen Kim, Sanjeev Noel, Sekhar P. Reddy, Hamid Rabb, Cheong-Hee Chang

Cell Rep. Author manuscript; available in PMC 2019 Sep 13.

Published in final edited form as: Cell Rep. 2019 Apr 16; 27(3): 699–707.e4. doi: 10.1016/j.celrep.2019.03.052

PMCID:: PMC6743333

Abstract Article PDF–1.0M

Select item 661370815.

ICOS deficiency hampers the homeostasis, development and function of NK cells

María Montes-Casado, Gloria Ojeda, Laura Aragoneses-Fenoll, Daniel López, Belén de Andrés, María Luisa Gaspar, Umberto Dianzani, José M. Rojo, Pilar Portolés

PLoS One. 2019; 14(7): e0219449. Published online 2019 Jul 8. doi: 10.1371/journal.pone.0219449

PMCID:: PMC6613708

Abstract Article PDF–3.5M

Select item 654786916.

Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance

Zinan Zhang, Florian Gothe, Perrine Pennamen, John R. James, David McDonald, Carlos P. Mata, Yorgo Modis, Anas M. Alazami, Meghan Acres, Wolfram Haller, Claire Bowen, Rainer Döffinger, Jan Sinclair, Shannon Brothers, Yu Zhang, Helen F. Matthews, Sophie Naudion, Fanny Pelluard, Huda Alajlan, Yasuhiro Yamazaki, Luigi D. Notarangelo, James E. Thaventhiran, Karin R. Engelhardt, Hamoud Al-Mousa, Sophie Hambleton, Caroline Rooryck, Kenneth G.C. Smith, Michael J. Lenardo

J Exp Med. 2019 Jun 3; 216(6): 1311–1327. Published online 2019 Apr 30. doi: 10.1084/jem.20182304

PMCID:: PMC6547869

Abstract Article PDF–3.6M

Select item 651913717.

Hematopoietic-Specific Deletion of Foxo1 Promotes NK Cell Specification and Proliferation

Pei Huang, Fangjie Wang, Yao Yang, Wenjing Lai, Meng Meng, Shuting Wu, Hongyan Peng, Lili Wang, Rixing Zhan, Saber Imani, Jianhua Yu, Bingbo Chen, Xiaohui Li, Youcai Deng

Front Immunol. 2019; 10: 1016. Published online 2019 May 8. doi: 10.3389/fimmu.2019.01016

PMCID:: PMC6519137

Abstract Article PDF–6.1M

Select item 624284318.

Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function

Fangjie Wang, Meng Meng, Banghui Mo, Yao Yang, Yan Ji, Pei Huang, Wenjing Lai, Xiaodong Pan, Tingting You, Hongqin Luo, Xiao Guan, Yafei Deng, Shunzong Yuan, Jianhong Chu, Michael Namaka, Tiffany Hughes, Lilin Ye, Jianhua Yu, Xiaohui Li, Youcai Deng

Nat Commun. 2018; 9: 4874. Published online 2018 Nov 19. doi: 10.1038/s41467-018-07277-9

PMCID:: PMC6242843

Abstract Article PDF–3.0M

Select item 578889019.

T Cells Engaging the Conserved MHC Class Ib Molecule Qa-1^b with TAP-Independent Peptides Are Semi-Invariant Lymphocytes

Elien M. Doorduijn, Marjolein Sluijter, Bianca J. Querido, Ursula J. E. Seidel, Claudia C. Oliveira, Sjoerd H. van der Burg, Thorbald van Hall

Front Immunol. 2018; 9: 60. Published online 2018 Jan 25. doi: 10.3389/fimmu.2018.00060

PMCID:: PMC5788890

Abstract Article PDF–2.5M

Select item 577277420.

The lysine acetyltransferase GCN5 is required for iNKT cell development through EGR2 acetylation

Yajun Wang, Chawon Yun, Beixue Gao, Yuanming Xu, Yana Zhang, Yiming Wang, Qingfei Kong, Fang Zhao, Chyung-Ru Wang, Sharon Y.R. Dent, Jian Wang, Xiangping Xu, Hua-Bin Li, Deyu Fang

Cell Rep. Author manuscript; available in PMC 2018 Jul 18.

Published in final edited form as: Cell Rep. 2017 Jul 18; 20(3): 600–612. doi: 10.1016/j.celrep.2017.06.065

PMCID:: PMC5772774

Abstract Article PDF–1.2M

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