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Select item 113472211.

Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn’s Disease

Thomas W Dennison, Rachel D Edgar, Felicity Payne, Komal M Nayak, Alexander D. B. Ross, Aurelie Cenier, Claire Glemas, Federica Giachero, April R Foster, Rebecca Harris, Judith Kraiczy, Camilla Salvestrini, Georgia Stavrou, Franco Torrente, Kimberley Brook, Claire Trayers, Rasa Elmentaite, Gehad Youssef, Bálint Tél, Douglas James Winton, Nefeli Skoufou-Papoutsaki, Sam Adler, Philip Bufler, Aline Azabdaftari, Andreas Jenke, Natasha G, Natasha Thomas, Erasmo Miele, Abdulrahman Al-Mohammad, Greta Guarda, Subra Kugathasan, Suresh Venkateswaran, Menna R Clatworthy, Tomas Castro-Dopico, Ondrej Suchanek, Caterina Strisciuglio, Marco Gasparetto, Seokjun Lee, Xingze Xu, Erica Bello, Namshik Han, Daniel R. Zerbino, Sarah A Teichmann, Josquin Nys, Robert Heuschkel, Francesca Perrone, Matthias Zilbauer

Gut. 2024 Sep; 73(9): 1464–1477. Published online 2024 Jun 10. doi: 10.1136/gutjnl-2024-332043

PMCID:: PMC11347221

Article PDF–8.2M

Select item 113353242.

Cutting Edge: Redundant Roles for MHC Class II–, CD1d-, and MR1-restricted T Cells in Clearing Bartonella Infection

Lena K. Siewert, Katja Fromm, Christoph Dehio, Daniel D. Pinschewer

J Immunol. 2024 Sep 1; 213(5): 553–558. Published online 2024 Jul 10. doi: 10.4049/jimmunol.2400045

PMCID:: PMC11335324

Article PDF–1.5M

Select item 92669953.

Alpha-1 Antitrypsin Reduces Disease Progression in a Mouse Model of Charcot-Marie-Tooth Type 1A: A Role for Decreased Inflammation and ADAM-17 Inhibition

Nikolay Zhukovsky, Marianna Silvano, Thierry Filloux, Sergio Gonzalez, Karl-Heinz Krause

Int J Mol Sci. 2022 Jul; 23(13): 7405. Published online 2022 Jul 3. doi: 10.3390/ijms23137405

PMCID:: PMC9266995

Article PDF–3.8M

Select item 90695274.

Inborn Errors of Immunity in Algerian Children and Adults: A Single-Center Experience Over a Period of 13 Years (2008–2021)

Brahim Belaid, Lydia Lamara Mahammed, Ouardia Drali, Aida Mohand Oussaid, Nabila Souad Touri, Souhila Melzi, Abdelhak Dehimi, Lylia Meriem Berkani, Fatma Merah, Zineb Larab, Ines Allam, Ouarda Khemici, Sonya Yasmine Kirane, Mounia Boutaba, Reda Belbouab, Hadjira Bekkakcha, Assia Guedouar, Abdelhakim Chelali, Brahim Baamara, Djamila Noui, Hadda Baaziz, Radia Rezak, Sidi Mohamed Azzouz, Malika Aichaoui, Assia Moktefi, Redha Mohamed Benhatchi, Meriem Oussalah, Naila Benaissa, Amel Laredj, Assia Bouchetara, Abdelkader Adria, Brahim Habireche, Noureddine Tounsi, Fella Dahmoun, Rabah Touati, Hamza Boucenna, Fadila Bouferoua, Lynda Sekfali, Nadjet Bouhafs, Rawda Aboura, Sakina Kherra, Yacine Inouri, Saadeddine Dib, Nawel Medouri, Noureddine Khelfaoui, Aicha Redjedal, Amara Zelaci, Samah Yahiaoui, Sihem Medjadj, Tahar Khelifi Touhami, Ahmed Kadi, Fouzia Amireche, Imane Frada, Shahrazed Houasnia, Karima Benarab, Chahynez Boubidi, Yacine Ferhani, Hayet Benalioua, Samia Sokhal, Nadia Benamar, Samira Aggoune, Karima Hadji, Asma Bellouti, Hakim Rahmoune, Nada Boutrid, kamelia Okka, Assia Ammour, Houssem Saadoune, Malika Amroun, Hayet Belhadj, Amina Ghanem, Hanane Abbaz, Sana Boudrioua, Besma Zebiche, Assia Ayad, Zahra Hamadache, Nassima Ouaras, Nassima Achour, Nadira Bouchair, Houda Boudiaf, Dahila Bekkat-Berkani, Hachemi Maouche, Zahir Bouzrar, Lynda Aissat, Ouardia Ibsaine, Belkacem Bioud, Leila Kedji, Djazia Dahlouk, Manoubia Bensmina, Abdelkarim Radoui, Mimouna Bessahraoui, Nadia Bensaadi, Azzeddine Mekki, Zoulikha Zeroual, Koon-Wing Chan, Daniel Leung, Amar Tebaibia, Soraya Ayoub, Dalila Mekideche, Merzak Gharnaout, Jean Laurent Casanova, Anne Puel, Yu Lung Lau, Nacira Cherif, Samir Ladj, Leila Smati, Rachida Boukari, Nafissa Benhalla, Reda Djidjik

Front Immunol. 2022; 13: 900091. Published online 2022 Apr 21. doi: 10.3389/fimmu.2022.900091

PMCID:: PMC9069527

Article PDF–2.3M

Select item 83435465.

Platelet MHC class I mediates CD8⁺ T-cell suppression during sepsis

Li Guo, Sikui Shen, Jesse W. Rowley, Neal D. Tolley, Wenwen Jia, Bhanu Kanth Manne, Kyra N. McComas, Ben Bolingbroke, Yasuhiro Kosaka, Krystin Krauel, Frederik Denorme, Shancy P. Jacob, Alicia S. Eustes, Robert A. Campbell, Elizabeth A. Middleton, Xiao He, Samuel M. Brown, Craig N. Morrell, Andrew S. Weyrich, Matthew T. Rondina

Blood. 2021 Aug 5; 138(5): 401–416. Prepublished online 2021 Apr 25. doi: 10.1182/blood.2020008958

PMCID:: PMC8343546

Article

Select item 79279196.

Efficient 5-OP-RU-Induced Enrichment of Mucosa-Associated Invariant T Cells in the Murine Lung Does Not Enhance Control of Aerosol Mycobacterium tuberculosis Infection

Charles Kyriakos Vorkas, Olivier Levy, Miroslav Skular, Kelin Li, Jeffrey Aubé, Michael S. Glickman

Infect Immun. 2021 Jan; 89(1): e00524-20. Prepublished online 2020 Oct 15. Published online 2020 Dec 15. doi: 10.1128/IAI.00524-20

PMCID:: PMC7927919

Article PDF–4.6M

Select item 77398447.

Rubella Virus-Associated Cutaneous Granulomatous Disease: a Unique Complication in Immune-Deficient Patients, Not Limited to DNA Repair Disorders

David Buchbinder, Fabian Hauck, Michael H. Albert, Anita Rack, Shahrzad Bakhtiar, Anna Shcherbina, Elena Deripapa, Kathleen E. Sullivan, Ludmila Perelygina, Marc Eloit, Bénédicte Neven, Philippe Pérot, Despina Moshous, Félipe Suarez, Christine Bodemer, Francisco A. Bonilla, Louise E. Vaz, Alfons L. Krol, Christoph Klein, Mikko Seppanen, Diane J. Nugent, Jasjit Singh, Hans D. Ochs

J Clin Immunol. Author manuscript; available in PMC 2020 Dec 16.

Published in final edited form as: J Clin Immunol. 2019 Jan; 39(1): 81–89. Published online 2019 Jan 3. doi: 10.1007/s10875-018-0581-0

PMCID:: PMC7739844

Article PDF–231K

Select item 69930848.

Histocompatibility Complex Status and Mendelian Randomization Analysis in Unsolved Antibody Deficiency

Hassan Abolhassani, Che Kang Lim, Asghar Aghamohammadi, Lennart Hammarström

Front Immunol. 2020; 11: 14. Published online 2020 Jan 24. doi: 10.3389/fimmu.2020.00014

PMCID:: PMC6993084

Article PDF–1.4M

Select item 69594199.

MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota

Motoko Koyama, Pamela Mukhopadhyay, Iona S Schuster, Andrea S Henden, Jan Hülsdünker, Antiopi Varelias, Marie Vetizou, Rachel D Kuns, Renee J Robb, Ping Zhang, Bruce R Blazar, Ranjeny Thomas, Jakob Begun, Nicola Waddell, Giorgio Trinchieri, Robert Zeiser, Andrew D Clouston, Mariapia A Degli-Esposti, Geoffrey R Hill

Immunity. Author manuscript; available in PMC 2020 Nov 19.

Published in final edited form as: Immunity. 2019 Nov 19; 51(5): 885–898.e7. Published online 2019 Sep 18. doi: 10.1016/j.immuni.2019.08.011

PMCID:: PMC6959419

Article PDF–2.2M

Select item 684453010.

Autophagy protein ATG5 regulates CD36 expression and anti-tumor MHC class II antigen presentation in dendritic cells

Dong Sun Oh, Heung Kyu Lee

Autophagy. 2019; 15(12): 2091–2106. Published online 2019 Apr 6. doi: 10.1080/15548627.2019.1596493

PMCID:: PMC6844530

Article PDF–5.2M

Select item 636970811.

Clinical, Immunological, and Molecular Findings in 57 Patients With Severe Combined Immunodeficiency (SCID) From India

Jahnavi Aluri, Mukesh Desai, Maya Gupta, Aparna Dalvi, Antony Terance, Sergio D. Rosenzweig, Jennifer L. Stoddard, Julie E. Niemela, Vasundhara Tamankar, Snehal Mhatre, Umair Bargir, Manasi Kulkarni, Nitin Shah, Amita Aggarwal, Harsha Prasada Lashkari, Vidya Krishna, Geeta Govindaraj, Manas Kalra, Manisha Madkaikar

Front Immunol. 2019; 10: 23. Published online 2019 Feb 4. doi: 10.3389/fimmu.2019.00023

PMCID:: PMC6369708

Article PDF–277K

Select item 635794112.

Relative Frequencies of Alloantigen-Specific Helper CD4 T Cells and B Cells Determine Mode of Antibody-Mediated Allograft Rejection

Jawaher Alsughayyir, Manu Chhabra, M. Saeed Qureshi, Mekhola Mallik, Jason M. Ali, Ivonne Gamper, Ellen L. Moseley, Sarah Peacock, Vasilis Kosmoliaptsis, Martin J. Goddard, Michelle A. Linterman, Reza Motallebzadeh, Gavin J. Pettigrew

Front Immunol. 2018; 9: 3039. Published online 2019 Jan 22. doi: 10.3389/fimmu.2018.03039

PMCID:: PMC6357941

Article PDF–3.4M

Select item 630933513.

Co-signaling receptors regulate T-cell plasticity and immune tolerance

Haitao Shen, Na Wu, Gayani Nanayakkara, Hangfei Fu, Qian Yang, William Y. Yang, Angus Li, Yu Sun, Charles Drummer, IV, Candice Johnson, Ying Shao, Luqiao Wang, Keman Xu, Wenhui Hu, Marion Chan, Vincent Tam, Eric T. Choi, Hong Wang, Xiaofeng Yang

Front Biosci (Landmark Ed) Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Front Biosci (Landmark Ed). 2019 Jan 1; 24: 96–132. Published online 2019 Jan 1. doi: 10.2741/4710

PMCID:: PMC6309335

Article PDF–3.9M

Select item 611863214.

Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells

Themis Alissafi, Aikaterini Hatzioannou, Konstantinos Mintzas, Roza Maria Barouni, Aggelos Banos, Sundary Sormendi, Alexandros Polyzos, Maria Xilouri, Ben Wielockx, Helen Gogas, Panayotis Verginis

J Clin Invest. 2018 Aug 31; 128(9): 3840–3852. Published online 2018 Aug 6. doi: 10.1172/JCI120888

PMCID:: PMC6118632

Article PDF–8.6M

Select item 597100715.

Ambient particulate matter activates the aryl hydrocarbon receptor in dendritic cells and enhances Th17 polarization

Alejandro R. Castañeda, Kent E. Pinkerton, Keith J. Bein, Alfonso Magaña-Méndez, Houa T. Yang, Paul Ashwood, Christoph F. A. Vogel

Toxicol Lett. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: Toxicol Lett. 2018 Aug; 292: 85–96. Published online 2018 Apr 22. doi: 10.1016/j.toxlet.2018.04.020

PMCID:: PMC5971007

Article PDF–1.0M

Select item 596057716.

March1 E3 Ubiquitin Ligase Modulates Features of Allergic Asthma in an Ovalbumin-Induced Mouse Model of Lung Inflammation

Osama A. Kishta, Antoine Sabourin, Leora Simon, Toby McGovern, Maxime Raymond, Tristan Galbas, Abdelilah Majdoubi, Satoshi Ishido, James G. Martin, Jacques Thibodeau

J Immunol Res. 2018; 2018: 3823910. Published online 2018 May 3. doi: 10.1155/2018/3823910

PMCID:: PMC5960577

Article PDF–6.3M

Select item 590999917.

Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development

Jeremy J. Racine, Isabel Stewart, Jeremy Ratiu, Greg Christianson, Emily Lowell, Kelsay Helm, Jennifer Allocco, Richard S. Maser, Yi-Guang Chen, Cathleen M. Lutz, Derry Roopenian, Jennifer Schloss, Teresa P. DiLorenzo, David V. Serreze

Diabetes. 2018 May; 67(5): 923–935. Published online 2018 Feb 22. doi: 10.2337/db17-1467

PMCID:: PMC5909999

Article PDF–2.2M

Select item 557656718.

Control of Treg differentiation by the transcription factors Thpok and LRF

Andrea C. Carpenter, Elizabeth Wohlfert, Laura B. Chopp, Melanie S. Vacchio, Jia Nie, Yongmei Zhao, Jyoti Shetty, Qi Xiao, Callie Deng, Bao Tran, Margaret Cam, Matthias M. Gaida, Yasmine Belkaid, Rémy Bosselut

J Immunol. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: J Immunol. 2017 Sep 1; 199(5): 1716–1728. Published online 2017 Jul 28. doi: 10.4049/jimmunol.1700181

PMCID:: PMC5576567

Article PDF–3.4M

Select item 536792319.

Helicobacter Infection Is Required for Inflammation and Colon Cancer in Smad3-Deficient Mice

Lillian Maggio-Price, Piper Treuting, Weiping Zeng, Mark Tsang, Helle Bielefeldt-Ohmann, Brian M. Iritani

Cancer Res. Author manuscript; available in PMC 2017 Mar 27.

Published in final edited form as: Cancer Res. 2006 Jan 15; 66(2): 828–838. doi: 10.1158/0008-5472.CAN-05-2448

PMCID:: PMC5367923

Article PDF–3.4M

Select item 532223220.

Age-associated B cells express a diverse repertoire of V_H and Vκ genes with somatic hypermutation

Lisa M. Russell Knode, Martin S. Naradikian, Arpita Myles, Jean L. Scholz, Yi Hao, Danya Liu, Mandy L. Ford, John W. Tobias, Michael P. Cancro, Patricia J. Gearhart

J Immunol. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: J Immunol. 2017 Mar 1; 198(5): 1921–1927. Published online 2017 Jan 16. doi: 10.4049/jimmunol.1601106

PMCID:: PMC5322232

Article PDF–1.2M

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