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Select item 42750691.

The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain

Sebastien Mosser, Jean-René Alattia, Mitko Dimitrov, Alexandre Matz, Justine Pascual, Bernard L. Schneider, Patrick C. Fraering

Hum Mol Genet. 2015 Jan 15; 24(2): 371–382. Published online 2014 Sep 1. doi: 10.1093/hmg/ddu449

PMCID:: PMC4275069

Abstract Article PDF–993K

Select item 39959772.

Impact of Apolipoprotein E on Alzheimer’s Disease

Paul S. Hauser, Robert O. Ryan

Curr Alzheimer Res. Author manuscript; available in PMC 2014 Apr 22.

Published in final edited form as: Curr Alzheimer Res. 2013 Oct; 10(8): 809–817. doi: 10.2174/15672050113109990156

PMCID:: PMC3995977

Abstract Article PDF–846K

Select item 40041743.

A Paired RNAi and RabGAP Overexpression Screen Identifies Rab11 as a Regulator of β-Amyloid Production

Vinod Udayar, Virginie Buggia-Prévot, Rita L. Guerreiro, Gabriele Siegel, Naresh Rambabu, Amanda L. Soohoo, Moorthi Ponnusamy, Barbara Siegenthaler, Jitin Bali, AESG, Rita Guerreiro, José Brás, Celeste Sassi, J. Raphael Gibbs, Dena Hernandez, Michelle K. Lupton, Kristelle Brown, Kevin Morgan, John Powell, Andrew Singleton, John Hardy, Mikael Simons, Jonas Ries, Manojkumar A. Puthenveedu, John Hardy, Gopal Thinakaran, Lawrence Rajendran

Cell Rep. Author manuscript; available in PMC 2014 Apr 29.

Published in final edited form as: Cell Rep. 2013 Dec 26; 5(6): 1536–1551. doi: 10.1016/j.celrep.2013.12.005

PMCID:: PMC4004174

Abstract Article PDF–1.8M

Select item 40059024.

THAOS: Gastrointestinal manifestations of transthyretin amyloidosis - common complications of a rare disease

Jonas Wixner, Rajiv Mundayat, Onur N Karayal, Intissar Anan, Pontus Karling, Ole B Suhr

Orphanet J Rare Dis. 2014; 9: 61. Published online 2014 Apr 27. doi: 10.1186/1750-1172-9-61

PMCID:: PMC4005902

Abstract Article PDF–463K

Select item 40182265.

APOE associations with severe CAA-associated vasculopathic changes – collaborative meta-analysis

Kristiina Rannikmäe, Rajesh N Kalaria, Steven M Greenberg, Helena C Chui, Frederick A Schmitt, Neshika Samarasekera, Rustam Al-Shahi Salman, Cathie LM Sudlow

J Neurol Neurosurg Psychiatry. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: J Neurol Neurosurg Psychiatry. 2014 Mar; 85(3): 300–305. Published online 2013 Oct 25. doi: 10.1136/jnnp-2013-306485

PMCID:: PMC4018226

Abstract Article PDF–1.4M

Select item 40495056.

A variant of green fluorescent protein exclusively deposited to active intracellular inclusion bodies

Govindan Raghunathan, Ganapathiraman Munussami, Hyojin Moon, Hyun-jong Paik, Seong Soo A An, Yong-Sung Kim, Sebyung Kang, Sun-Gu Lee

Microb Cell Fact. 2014; 13: 68. Published online 2014 May 16. doi: 10.1186/1475-2859-13-68

PMCID:: PMC4049505

Abstract Article PDF–2.4M

Select item 40672227.

A Neuroprotective Brain-penetrating Endopeptidase Fusion Protein Ameliorates Alzheimer Disease Pathology and Restores Neurogenesis

Brian Spencer, Inder Verma, Paula Desplats, Dinorah Morvinski, Ed Rockenstein, Anthony Adame, Eliezer Masliah

J Biol Chem. 2014 Jun 20; 289(25): 17917–17931. Published online 2014 May 13. doi: 10.1074/jbc.M114.557439

PMCID:: PMC4067222

Abstract Article PDF–4.7M

Select item 40844628.

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

Georg Meisl, Xiaoting Yang, Erik Hellstrand, Birgitta Frohm, Julius B. Kirkegaard, Samuel I. A. Cohen, Christopher M. Dobson, Sara Linse, Tuomas P. J. Knowles

Proc Natl Acad Sci U S A. 2014 Jul 1; 111(26): 9384–9389. Published online 2014 Jun 17. doi: 10.1073/pnas.1401564111

PMCID:: PMC4084462

Abstract Article PDF–1.2M

Select item 41165989.

Proliferation, differentiation and amyloid-β production in neural progenitor cells isolated from TgCRND8 mice

S. Kanemoto, J. Griffin, K. Markham-Coultes, I. Aubert, A. Tandon, P.S. George-Hyslop, P.E. Fraser

Neuroscience. 2014 Mar 7; 261(100): 52–59. doi: 10.1016/j.neuroscience.2013.12.021

PMCID:: PMC4116598

Abstract Article PDF–769K

Select item 417801210.

General Amyloid Inhibitors? A Critical Examination of the Inhibition of IAPP Amyloid Formation by Inositol Stereoisomers

Hui Wang, Daniel P. Raleigh

PLoS One. 2014; 9(9): e104023. Published online 2014 Sep 26. doi: 10.1371/journal.pone.0104023

PMCID:: PMC4178012

Abstract Article PDF–831K

Select item 418381211.

Non-chaperone Proteins Can Inhibit Aggregation and Cytotoxicity of Alzheimer Amyloid β Peptide

Jinghui Luo, Sebastian K. T. S. Wärmländer, Astrid Gräslund, Jan Pieter Abrahams

J Biol Chem. 2014 Oct 3; 289(40): 27766–27775. Published online 2014 Aug 6. doi: 10.1074/jbc.M114.574947

PMCID:: PMC4183812

Abstract Article PDF–2.9M

Select item 421530512.

Two novel DNA motifs are essential for BACE1 gene transcription

Yan Xiang, Shasha Meng, Jinfeng Wang, Songyang Li, Jingru Liu, Hongmei Li, Tingyu Li, Weihong Song, Weihui Zhou

Sci Rep. 2014; 4: 6864. Published online 2014 Oct 31. doi: 10.1038/srep06864

PMCID:: PMC4215305

Abstract Article PDF–2.0M

Select item 424509513.

EGb761 Provides a Protective Effect against Aβ_1-42 Oligomer-Induced Cell Damage and Blood-Brain Barrier Disruption in an In Vitro bEnd.3 Endothelial Model

Wen-bin Wan, Lan Cao, Lu-mei Liu, Bill Kalionis, Chuan Chen, Xian-tao Tai, Ya-ming Li, Shi-jin Xia

PLoS One. 2014; 9(11): e113126. Published online 2014 Nov 26. doi: 10.1371/journal.pone.0113126

PMCID:: PMC4245095

Abstract Article PDF–1.0M

Select item 425631314.

Amyloid Formation by Human Carboxypeptidase D Transthyretin-like Domain under Physiological Conditions

Javier Garcia-Pardo, Ricardo Graña-Montes, Marc Fernandez-Mendez, Angels Ruyra, Nerea Roher, Francesc X. Aviles, Julia Lorenzo, Salvador Ventura

J Biol Chem. 2014 Dec 5; 289(49): 33783–33796. Published online 2014 Oct 7. doi: 10.1074/jbc.M114.594804

PMCID:: PMC4256313

Abstract Article PDF–4.0M

Select item 425983315.

Iron Increases APP Translation and Amyloid-Beta Production in the Retina

Lucie Y. Guo, Oleg Alekseev, Yafeng Li, Ying Song, Joshua L. Dunaief

Exp Eye Res. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Exp Eye Res. 2014 Dec; 129: 31–37. Published online 2014 Oct 16. doi: 10.1016/j.exer.2014.10.012

PMCID:: PMC4259833

Abstract Article PDF–968K

Select item 427054416.

Evidence of the presence of amyloid substance in the blood of familial amyloidotic polyneuropathy patients with ATTR Val30Met mutation

Jinping Liu, Jie Lan, Peng Zhao, Fang Zheng, Jingjing Song, Peilan Zhang, Xuguo Sun

Int J Clin Exp Pathol. 2014; 7(11): 7795–7800. Published online 2014 Oct 15.

PMCID:: PMC4270544

Abstract Article PDF–796K

Select item 397230417.

TREM2 and the neuroimmunology of Alzheimer’s disease

Suzanne E. Hickman, Joseph El Khoury

Biochem Pharmacol. Author manuscript; available in PMC 2015 Apr 15.

Published in final edited form as: Biochem Pharmacol. 2014 Apr 15; 88(4): 495–498. Published online 2013 Dec 16. doi: 10.1016/j.bcp.2013.11.021

PMCID:: PMC3972304

Abstract Article PDF–324K

Select item 429390118.

Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage

Pallavi Manral, Natàlia Reixach

Biosci Rep. 2015; 35(1): e00172. Prepublished online 2014 Nov 13. Published online 2015 Jan 14. doi: 10.1042/BSR20140155

PMCID:: PMC4293901

Abstract Article PDF–816K

Select item 430331019.

Cooperative Stabilization of Transthyretin by Clusterin and Diflunisal

Michael J. Greene, Elena S. Klimtchuk, David C. Seldin, John L. Berk, Lawreen H. Connors

Biochemistry. 2015 Jan 20; 54(2): 268–278. Published online 2014 Dec 5. doi: 10.1021/bi5011249

PMCID:: PMC4303310

Abstract Article PDF–3.0M

Select item 433415020.

Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain

Eloise Hudry, Jonathan Dashkoff, Alysson D. Roe, Shuko Takeda, Robert M. Koffie, Tadafumi Hashimoto, Maria Scheel, Tara Spires-Jones, Michal Arbel-Ornath, Rebecca Betensky, Beverly L. Davidson, Bradley T. Hyman

Sci Transl Med. Author manuscript; available in PMC 2015 Feb 19.

Published in final edited form as: Sci Transl Med. 2013 Nov 20; 5(212): 212ra161. doi: 10.1126/scitranslmed.3007000

PMCID:: PMC4334150

Abstract Article PDF–1.3M

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