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Items: 1 to 20 of 303

1.
Cardiotoxicity of CPX-351 in children and adolescents with relapsed AML: a Children's Oncology Group report
Kasey J. Leger, Michael J. Absalon, Biniyam G. Demissei, Amanda M. Smith, Robert B. Gerbing, Todd A. Alonzo, Hari K. Narayan, Betsy A. Hirsch, Jessica A. Pollard, Bassem I. Razzouk, Kelly D. Getz, Richard Aplenc, E. Anders Kolb, Bonnie Ky, Todd M. Cooper
Front Cardiovasc Med. 2024; 11: 1347547. Published online 2024 Jun 14. doi: 10.3389/fcvm.2024.1347547
PMCID:
PMC11211570
AbstractArticlePDF–1.3M
2.
A phase 1/2 study of NS-87/CPX-351 (cytarabine and daunorubicin liposome) in Japanese patients with high-risk acute myeloid leukemia
Kensuke Usuki, Toshihiro Miyamoto, Takuji Yamauchi, Kiyoshi Ando, Yoshiaki Ogawa, Masahiro Onozawa, Takahiro Yamauchi, Hitoshi Kiyoi, Akira Yokota, Takayuki Ikezoe, Yuna Katsuoka, Satoru Takada, Nobuyuki Aotsuka, Yasuyoshi Morita, Takayuki Ishikawa, Noboru Asada, Shuichi Ota, Atsushi Dohi, Kensaku Morimoto, Shunji Imai, Umi Kishimoto, Koichi Akashi, Yasushi Miyazaki, The Study Group for NS-87/CPX-351
Int J Hematol. 2024; 119(6): 647–659. Published online 2024 Mar 26. doi: 10.1007/s12185-024-03733-z
PMCID:
PMC11136735
AbstractArticlePDF–756K
3.
CPX-351 Pharmacokinetics and Safety in Adults with Hematologic Malignancies and Renal Function Impairment: Phase 1 Trial
Scott R. Solomon, Bayard L. Powell, Jamie Koprivnikar, Catherine Lai, Heather Male, Laura C. Michaelis, Laura F. Newell, David Sanford, Jack Jenkins, Amy Zelaya, Sheryl Coppola, Stefan Faderl, Roland B. Walter
Cancers (Basel) 2024 Mar; 16(5): 915. Published online 2024 Feb 24. doi: 10.3390/cancers16050915
PMCID:
PMC10931427
AbstractArticlePDF–674K
4.
The origin, dissemination, and molecular networks of HIV-1 CRF65_cpx strain in Hainan Island, China
Dee Yu, Kaokao Zhu, Mu Li, Fei Zhang, Yuan Yang, Chunyun Lu, Shanmei Zhong, Cai Qin, Yanan Lan, Jipeng Yu, Jindong Ding Petersen, Junjun Jiang, Hao Liang, Li Ye, Bingyu Liang
BMC Infect Dis. 2024; 24: 269. Published online 2024 Mar 1. doi: 10.1186/s12879-024-09101-w
PMCID:
PMC10905908
AbstractArticlePDF–1.7M
5.
CPX-351 and allogeneic stem cell transplant for a therapy-related acute myeloid leukemia that developed after treatment of acute promyelocytic leukemia: a case report and review of the literature
Alessandra Sperotto, Maria Teresa Lupo Stanghellini, Jacopo Peccatori, Roberta De Marchi, Simona Piemontese, Giulia Ciotti, Marco Basso, Elisabetta Pierdomenico, Paolo Fiore, Fabio Ciceri, Michele Gottardi
Front Oncol. 2023; 13: 1291457. Published online 2024 Jan 25. doi: 10.3389/fonc.2023.1291457
PMCID:
PMC10850225
AbstractArticlePDF–654K
6.
RavA‐ViaA antibiotic response is linked to Cpx and Zra2 envelope stress systems in Vibrio cholerae
Evelyne Krin, André Carvalho, Manon Lang, Anamaria Babosan, Didier Mazel, Zeynep Baharoglu
Microbiol Spectr. 2023 Nov-Dec; 11(6): e01730-23. Published online 2023 Oct 20. doi: 10.1128/spectrum.01730-23
PMCID:
PMC10848872
AbstractArticlePDF–1.8M
7.
Comprehensive Genetic Characterization of Four Novel HIV-1 Circulating Recombinant Forms (CRF129_56G, CRF130_A1B, CRF131_A1B, and CRF138_cpx): Insights from Molecular Epidemiology in Cyprus
Cicek Topcu, Vasilis Georgiou, Johana Hezka Rodosthenous, Georgios Siakallis, Elena Katerina Gavala, Christiana Reveka Dimitriou, Evgenia Zeniou, Brian Thomas Foley, Leondios G. Kostrikis
Viruses. 2024 Jan; 16(1): 19. Published online 2023 Dec 21. doi: 10.3390/v16010019
PMCID:
PMC10819958
AbstractArticlePDF–8.5M
8.
CPX, a selective A1-adenosine-receptor antagonist, regulates intracellular pH in cystic fibrosis cells
VALERIA CASAVOLA, R. JAMES TURNER, COLLEEN GUAY-BRODER, KENNETH A. JACOBSON, OFER EIDELMAN, HARVEY B. POLLARD
Am J Physiol. Author manuscript; available in PMC 2024 Jan 18.
Published in final edited form as: Am J Physiol. 1995 Jul; 269(1 Pt 1): C226–C233. doi: 10.1152/ajpcell.1995.269.1.C226
PMCID:
PMC10794913
AbstractArticlePDF–1.1M
9.
CPX-351 in FLT3-mutated acute myeloid leukemia
Claire Andrews, Vinod Pullarkat, Christian Recher
Front Oncol. 2023; 13: 1271722. Published online 2023 Nov 17. doi: 10.3389/fonc.2023.1271722
PMCID:
PMC10691756
AbstractArticlePDF–632K
10.
Lower cardiotoxicity of CPX-351 relative to daunorubicin plus cytarabine free-drug combination in hiPSC-derived cardiomyocytes in vitro
Marie C. Fortin, Andrew S. LaCroix, Tom N. Grammatopoulos, Lei Tan, Qi Wang, Dino Manca
Sci Rep. 2023; 13: 21054. Published online 2023 Nov 29. doi: 10.1038/s41598-023-47293-4
PMCID:
PMC10686991
AbstractArticlePDF–3.0M
11.
A randomized comparison of CPX-351 and FLAG-Ida in adverse karyotype AML and high-risk MDS: the UK NCRI AML19 trial
Jad Othman, Charlotte Wilhelm-Benartzi, Richard Dillon, Steve Knapper, Sylvie D. Freeman, Leona M. Batten, Joanna Canham, Emily L. Hinson, Julie Wych, Sophie Betteridge, William Villiers, Michelle Kleeman, Amanda Gilkes, Nicola Potter, Ulrik Malthe Overgaard, Priyanka Mehta, Panagiotis Kottaridis, Jamie Cavenagh, Claire Hemmaway, Claire Arnold, Mike Dennis, Nigel H. Russell, UK National Cancer Research Institute Acute Myeloid Leukaemia Working Group
Blood Adv. 2023 Aug 22; 7(16): 4539–4549. Published online 2023 May 16. doi: 10.1182/bloodadvances.2023010276
PMCID:
PMC10425682
AbstractArticlePDF–597K
12.
Clinical outcomes after CPX‐351 in patients with high‐risk acute myeloid leukemia: A comparison with a matched cohort from the Spanish PETHEMA registry
Teresa Bernal, Ainhoa Fernández Moreno, Almudena de LaIglesia, Celina Benavente, Ana García‐Noblejas, Daniel García Belmonte, Rosalía Riaza, Olga Salamero, Maria Angeles Foncillas, Alicia Roldán, Víctor Noriega Concepción, Laura Llorente González, Juan Miguel Bergua Burgués, Soraya Lorente de Uña, Gabriela Rodríguez‐Macías, Adolfo de la Fuente Burguera, Maria José García Pérez, Jose Luis López‐Lorenzo, Pilar Martínez, Concepción Aláez, Marta Callejas, Carmen Martínez‐Chamorro, José Rifón Roca, Lourdes Amador Barciela, Armando V. Mena Durán, Karoll Gómez Correcha, Esperanza Lavilla Rubira, María Luz Amigo, Ferran Vall‐llovera, Ana Garrido, María García‐Fortes, Dunia de Miguel Llorente, Anastasia Aules Leonardo, Carlos Cervero, Rosa Coll Jordá, Manuel M. Pérez‐Encinas, Marta Polo Zarzuela, Angela Figuera, Guillermo Rad, David Martínez‐Cuadrón, Pau Montesinos
Cancer Med. 2023 Jul; 12(14): 14892–14901. Published online 2023 May 22. doi: 10.1002/cam4.6120
PMCID:
PMC10417130
AbstractArticlePDF–509K
13.
Multicenter Observational Retrospective Study on Febrile Events in Patients with Acute Myeloid Leukemia Treated with Cpx-351 in “Real-Life”: The SEIFEM Experience
Luana Fianchi, Fabio Guolo, Francesco Marchesi, Chiara Cattaneo, Michele Gottardi, Francesco Restuccia, Anna Candoni, Elettra Ortu La Barbera, Rita Fazzi, Crescenza Pasciolla, Olimpia Finizio, Nicola Fracchiolla, Mario Delia, Federica Lessi, Michelina Dargenio, Valentina Bonuomo, Maria Ilaria Del Principe, Patrizia Zappasodi, Marco Picardi, Claudia Basilico, Monica Piedimonte, Paola Minetto, Antonio Giordano, Patrizia Chiusolo, Lucia Prezioso, Caterina Buquicchio, Lorella Maria Antonia Melillo, Daniele Zama, Francesca Farina, Valentina Mancini, Irene Terrenato, Michela Rondoni, Irene Urbino, Mario Tumbarello, Alessandro Busca, Livio Pagano
Cancers (Basel) 2023 Jul; 15(13): 3457. Published online 2023 Jul 1. doi: 10.3390/cancers15133457
PMCID:
PMC10341225
AbstractArticlePDF–749K
14.
NlpE Is an OmpA-Associated Outer Membrane Sensor of the Cpx Envelope Stress Response
Timothy H. S. Cho, Junshu Wang, Tracy L. Raivio
J Bacteriol. 2023 Apr; 205(4): e00407-22. Published online 2023 Apr 6. doi: 10.1128/jb.00407-22
PMCID:
PMC10127795
AbstractArticlePDF–1.6M
15.
Salmonella Typhimurium uses the Cpx stress response to detect N-chlorotaurine and promote the repair of oxidized proteins
Camille Andrieu, Laurent Loiseau, Alexandra Vergnes, Séverine Gagnot, Romain Barré, Laurent Aussel, Jean-François Collet, Benjamin Ezraty
Proc Natl Acad Sci U S A. 2023 Apr 4; 120(14): e2215997120. Published online 2023 Mar 28. doi: 10.1073/pnas.2215997120
PMCID:
PMC10083560
AbstractArticlePDF–1.1M
16.
Reliability of resting metabolic rate between and within day measurements using the Vyntus CPX system and comparison against predictive formulas
J. Iraki, G. Paulsen, I. Garthe, G. Slater, J.L. Areta
Nutr Health. 2023 Mar; 29(1): 107–114. Published online 2021 Dec 21. doi: 10.1177/02601060211057324
PMCID:
PMC10009490
AbstractArticlePDF–972K
17.
YihE is a novel binding partner of Rho and regulates Rho-dependent transcription termination in the Cpx stress response
Biying Wang, Hairun Pei, Zhifang Lu, Yingying Xu, Shengnan Han, Zongchao Jia, Jimin Zheng
iScience. 2022 Dec 22; 25(12): 105483. Published online 2022 Nov 2. doi: 10.1016/j.isci.2022.105483
PMCID:
PMC9663540
AbstractArticlePDF–5.5M
18.
Identification of a new circulating recombinant form of human immunodeficiency virus type 1, CRF124_cpx involving subtypes A, G, H, and CRF27_cpx in Angola
Rayana Katylin Mendes Da Silva, Joana Morais, Brian Thomas Foley, Gonzalo Bello, Mariza Gonçalves Morgado, Monick Lindenmeyer Guimarães
Front Microbiol. 2022; 13: 992640. Published online 2022 Oct 17. doi: 10.3389/fmicb.2022.992640
PMCID:
PMC9619209
AbstractArticlePDF–3.5M
19.
Efficacy and safety of CPX-351 versus 7 + 3 chemotherapy by European LeukemiaNet 2017 risk subgroups in older adults with newly diagnosed, high-risk/secondary AML: post hoc analysis of a randomized, phase 3 trial
Jorge E. Cortes, Tara L. Lin, Kobby Asubonteng, Stefan Faderl, Jeffrey E. Lancet, Thomas Prebet
J Hematol Oncol. 2022; 15: 155. Published online 2022 Oct 26. doi: 10.1186/s13045-022-01361-w
PMCID:
PMC9598030
AbstractArticlePDF–1.4M
20.
Simulated Colonic Fluid Replicates the In Vivo Growth Capabilities of Citrobacter rodentiumcpxRA Mutants and Uncovers Additive Effects of Cpx-Regulated Genes on Fitness
Ashley Gilliland, Christina Gavino, Samantha Gruenheid, Tracy Raivio
Infect Immun. 2022 Sep; 90(9): e00314-22. Published online 2022 Aug 24. doi: 10.1128/iai.00314-22
PMCID:
PMC9476912
AbstractArticlePDF–2.0M

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