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Select item 90699261.

Xeroderma Pigmentosum Complementation Group C (XPC): Emerging Roles in Non-Dermatologic Malignancies

Nawar Al Nasrallah, Benjamin M. Wiese, Catherine R. Sears

Front Oncol. 2022; 12: 846965. Published online 2022 Apr 21. doi: 10.3389/fonc.2022.846965

PMCID:: PMC9069926

Abstract Article PDF–2.0M

Select item 67469392.

A Novel Drug Resistance Mechanism: Genetic Loss of Xeroderma Pigmentosum Complementation Group C (XPC) Enhances Glycolysis-Mediated Drug Resistance in DLD-1 Colon Cancer Cells

Yu Han, Yuan Qing Qu, Simon Wing Fai Mok, Juan Chen, Cheng Lai Xia, Hu Qiang He, Zheng Li, Wei Zhang, Cong Ling Qiu, Liang Liu, Betty Yuen Kwan Law, Vincent Kam Wai Wong

Front Pharmacol. 2019; 10: 912. Published online 2019 Sep 10. doi: 10.3389/fphar.2019.00912

PMCID:: PMC6746939

Abstract Article PDF–3.2M

Select item 62478233.

Astaxanthin enhances erlotinib-induced cytotoxicity by p38 MAPK mediated xeroderma pigmentosum complementation group C (XPC) down-regulation in human lung cancer cells

Jyh-Cheng Chen, Chia-Hung Wu, Yi-Shuan Peng, Hao-Yu Zheng, Yuan-Cheng Lin, Peng-Fang Ma, Ting-Chuan Yen, Tzu-Ying Chen, Yun-Wei Lin

Toxicol Res (Camb) 2018 Nov 1; 7(6): 1247–1256. Published online 2018 Sep 19. doi: 10.1039/c7tx00292k

PMCID:: PMC6247823

Abstract Article

Select item 39083924.

Binding of HIV-1 Vpr Protein to the Human Homolog of the Yeast DNA Repair Protein RAD23 (hHR23A) Requires Its Xeroderma Pigmentosum Complementation Group C Binding (XPCB) Domain as Well as the Ubiquitin-associated 2 (UBA2) Domain

Jinwon Jung, In-Ja L. Byeon, Maria DeLucia, Leonardus M. I. Koharudin, Jinwoo Ahn, Angela M. Gronenborn

J Biol Chem. 2014 Jan 31; 289(5): 2577–2588. Published online 2013 Dec 8. doi: 10.1074/jbc.M113.534453

PMCID:: PMC3908392

Abstract Article PDF–3.0M

Select item 38257625.

Xeroderma pigmentosum complementation group C protein (XPC) serves as a general sensor of damaged DNA

Steven M. Shell, Edward K. Hawkins, Miaw-Sheue Tsai, Aye Su Hlaing, Carmelo J. Rizzo, Walter J. Chazin

DNA Repair (Amst) Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: DNA Repair (Amst). 2013 Nov; 12(11): 10.1016/j.dnarep.2013.08.013. Published online 2013 Sep 17. doi: 10.1016/j.dnarep.2013.08.013

PMCID:: PMC3825762

Abstract Article PDF–1.4M

Select item 25799636.

Biochemical and Structural Domain-Analysis of XPC

Christopher G. Bunick, Michael R. Miller, Brian E. Fuller, Ellen Fanning, Walter J. Chazin

Biochemistry. Author manuscript; available in PMC 2008 Nov 6.

Published in final edited form as: Biochemistry. 2006 Dec 19; 45(50): 14965–14979. doi: 10.1021/bi061370o

PMCID:: PMC2579963

Abstract Article PDF–2.5M

Select item 23909067.

XPC genotypes/diplotypes play no independent or interaction role with PAH-DNA adducts for breast cancer risk

Jing Shen, Marilie D. Gammon, Mary Beth Terry, Susan L. Teitelbaum, Sybil M. Eng, Alfred I. Neugut, Regina M. Santella

Eur J Cancer. Author manuscript; available in PMC 2009 Mar 1.

Published in final edited form as: Eur J Cancer. 2008 Mar; 44(5): 710–717. Published online 2007 Nov 28. doi: 10.1016/j.ejca.2007.10.027

PMCID:: PMC2390906

Abstract Article PDF–309K

Select item 5235748.

Cloning the Drosophila homolog of the xeroderma pigmentosum complementation group C gene reveals homology between the predicted human and Drosophila polypeptides and that encoded by the yeast RAD4 gene.

K A Henning, C Peterson, R Legerski, E C Friedberg

Nucleic Acids Res. 1994 Feb 11; 22(3): 257–261. doi: 10.1093/nar/22.3.257

PMCID:: PMC523574

Summary Page Browse PDF–1.0M

Select item 3612289.

Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes.

J Venema, A van Hoffen, V Karcagi, A T Natarajan, A A van Zeeland, L H Mullenders

Mol Cell Biol. 1991 Aug; 11(8): 4128–4134. doi: 10.1128/mcb.11.8.4128

PMCID:: PMC361228

Summary Page Browse PDF–1.4M

Select item 33344610.

The residual repair capacity of xeroderma pigmentosum complementation group C fibroblasts is highly specific for transcriptionally active DNA.

J Venema, A van Hoffen, A T Natarajan, A A van Zeeland, L H Mullenders

Nucleic Acids Res. 1990 Feb 11; 18(3): 443–448. doi: 10.1093/nar/18.3.443

PMCID:: PMC333446

Summary Page Browse PDF–1.4M

Select item 1104841511.

XPC Protects against Carcinogen-Induced Histologic Progression to Lung Squamous Cell Carcinoma by Reduced Basal Epithelial Cell Proliferation

Catherine R. Sears, Huaxin Zhou, Emily Hulsey, Bea A. Aidoo, George E. Sandusky, Nawar Al Nasrallah

Cancers (Basel) 2024 Apr; 16(8): 1495. Published online 2024 Apr 13. doi: 10.3390/cancers16081495

PMCID:: PMC11048415

Abstract Article PDF–6.9M

Select item 1102711012.

Clinical prognostic significance of xeroderma pigmentosum group C and IFN‑γ in non‑small cell lung cancer

Yongming Wang, Weiyu Wang, Huaijie Wang, Liya Qin, Meijia Zhang, Yong Zhang, Yubing Wang, Changcheng Hao, Meihua Qu, Gongchao Wang

Oncol Lett. 2024 Jun; 27(6): 259. Published online 2024 Apr 9. doi: 10.3892/ol.2024.14392

PMCID:: PMC11027110

Abstract Article PDF–2.9M

Select item 1097213413.

The Role of DNA Repair (XPC, XPD, XPF, and XPG) Gene Polymorphisms in the Development of Myeloproliferative Neoplasms

Adriana-Stela Crișan, Florin Tripon, Alina Bogliș, George-Andrei Crauciuc, Adrian P. Trifa, Erzsébet Lázár, Ioan Macarie, Manuela Rozalia Gabor, Claudia Bănescu

Medicina (Kaunas) 2024 Mar; 60(3): 506. Published online 2024 Mar 19. doi: 10.3390/medicina60030506

PMCID:: PMC10972134

Abstract Article PDF–717K

Select item 1091172314.

Genetic Polymorphisms of XPC, XPD, XPG Genes and their Association with Radiotherapy Induced Toxicity among Head and Neck Cancer Patients: A Hospital Based Study from Maharashtra

Anand K. Gudur, Shivani R. Kale, Rashmi A. Gudur, Suresh J. Bhosale, Kailas D. Datkhile

Asian Pac J Cancer Prev. 2024; 25(1): 191–199. doi: 10.31557/APJCP.2024.25.1.191

PMCID:: PMC10911723

Abstract Article PDF–492K

Select item 1086887515.

Familial Melanoma Phenotype With Xeroderma Pigmentosum Group C (XP-C) Genotype - The Putative Role of MC1R Polymorphism as Modifier

Franciele Antonieta Bianchi Leidenz, Flavia Vasques Bittencourt, Williana Garcia Braga, Elio Magno de Sá Araújo, Carolina Cavalieri Gomes, Vanessa de Fatima Bernardes, Eitan Friedman, Luiz De Marco

Dermatol Pract Concept. 2024 Jan; 14(1): e2024050. Published online 2024 Jan 1. doi: 10.5826/dpc.1401a50