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Select item 68126821.

A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB

Zixu Liu, Katrina B. Mar, Natasha W. Hanners, Sofya S. Perelman, Mohammed Kanchwala, Chao Xing, John W. Schoggins, Neal M. Alto

Nature. Author manuscript; available in PMC 2019 Oct 24.

Published in final edited form as: Nature. 2019 Apr; 568(7751): 249–253. Published online 2019 Mar 20. doi: 10.1038/s41586-019-1041-6

PMCID:: PMC6812682

Abstract Article PDF–4.2M

Select item 64894152.

A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas

Jeffrey R Gehlhausen, Eric Hawley, Benjamin Mark Wahle, Yongzheng He, Donna Edwards, Steven D Rhodes, Jacquelyn D Lajiness, Karl Staser, Shi Chen, Xianlin Yang, Jin Yuan, Xiaohong Li, Li Jiang, Abbi Smith, Waylan Bessler, George Sandusky, Anat Stemmer-Rachamimov, Timothy J Stuhlmiller, Steven P Angus, Gary L Johnson, Grzegorz Nalepa, Charles W Yates, D Wade Clapp, Su-Jung Park

Hum Mol Genet. 2019 Feb 15; 28(4): 572–583. Published online 2018 Oct 17. doi: 10.1093/hmg/ddy361

PMCID:: PMC6489415

Abstract Article PDF–11M

Select item 60502723.

A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling

Kislay Parvatiyar, Jose Pindado, Anurupa Dev, Saba Roghiyh Aliyari, Shivam A. Zaver, Hoda Gerami, Maxime Chapon, Amir A. Ghaffari, Anant Dhingra, Genhong Cheng

Nat Commun. 2018; 9: 2770. Published online 2018 Jul 17. doi: 10.1038/s41467-018-05168-7

PMCID:: PMC6050272

Abstract Article PDF–1.0M

Select item 232704.

Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of Nuclear Factor-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

Ho Yeong Song, Catherine H. Régnier, Carsten J. Kirschning, David V. Goeddel, Mike Rothe

Proc Natl Acad Sci U S A. 1997 Sep 2; 94(18): 9792–9796. doi: 10.1073/pnas.94.18.9792

PMCID:: PMC23270

Abstract Article PDF–427K

Select item 199165.

NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176

Lei Ling, Zhaodan Cao, David V. Goeddel

Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7): 3792–3797. doi: 10.1073/pnas.95.7.3792

PMCID:: PMC19916

Abstract Article PDF–333K

Select item 67215876.

Long Non-Coding RNAs Target Pathogenetically Relevant Genes and Pathways in Rheumatoid Arthritis

Marzia Dolcino, Elisa Tinazzi, Antonio Puccetti, Claudio Lunardi

Cells. 2019 Aug; 8(8): 816. Published online 2019 Aug 2. doi: 10.3390/cells8080816

PMCID:: PMC6721587

Abstract Article PDF–1.0M

Select item 47342227.

Expression levels of cytokines and chemokines increase in human peripheral blood mononuclear cells stimulated by activation of the Toll-like receptor 5 pathway

YU MA, LI ZHANG, QUANSHENG LI

Exp Ther Med. 2016 Feb; 11(2): 588–592. Published online 2015 Dec 4. doi: 10.3892/etm.2015.2914

PMCID:: PMC4734222

Abstract Article PDF–425K

Select item 43520568.

The Role of Misshapen NCK-related kinase (MINK), a Novel Ste20 Family Kinase, in the IRES-Mediated Protein Translation of Human Enterovirus 71

Shi Yun Leong, Bryan Kit Teck Ong, Justin Jang Hann Chu

PLoS Pathog. 2015 Mar; 11(3): e1004686. Published online 2015 Mar 6. doi: 10.1371/journal.ppat.1004686

PMCID:: PMC4352056

Abstract Article PDF–2.4M

Select item 42187059.

Toll-like receptor 4 agonist, lipopolysaccharide, increases the expression levels of cytokines and chemokines in human peripheral blood mononuclear cells

DAN PU, WEI WANG

Exp Ther Med. 2014 Dec; 8(6): 1914–1918. Published online 2014 Oct 15. doi: 10.3892/etm.2014.2025

PMCID:: PMC4218705

Abstract Article PDF–499K

Select item 406595010.

Interferon-α response in chronic hepatitis B-transfected HepG2.2.15 cells is partially restored by lamivudine treatment

Shi-He Guan, Mengji Lu, Petra Grünewald, Michael Roggendorf, Guido Gerken, Jörg F Schlaak

World J Gastroenterol. 2007 Jan 14; 13(2): 228–235. Published online 2007 Jan 14. doi: 10.3748/wjg.v13.i2.228

PMCID:: PMC4065950

Abstract Article PDF–1.0M

Select item 396284011.

Gene Expression Profile in Human Skeletal Muscle Cells Infected With Human Adenovirus Type 36

Zhong Q. Wang, Yongmei Yu, Xian H. Zhang, Jianhua Qin, Elizabeth Floyd

J Med Virol. Author manuscript; available in PMC 2014 Mar 24.

Published in final edited form as: J Med Virol. 2012 Aug; 84(8): 1254–1266. doi: 10.1002/jmv.23332

PMCID:: PMC3962840

Abstract Article PDF–2.6M

Select item 386272712.

Whole Exome Sequencing Identifies Novel Recurrently Mutated Genes in Patients with Splenic Marginal Zone Lymphoma

Marina Parry, Matthew J. J. Rose-Zerilli, Jane Gibson, Sarah Ennis, Renata Walewska, Jade Forster, Helen Parker, Zadie Davis, Anne Gardiner, Andrew Collins, David G. Oscier, Jonathan C. Strefford

PLoS One. 2013; 8(12): e83244. Published online 2013 Dec 13. doi: 10.1371/journal.pone.0083244

PMCID:: PMC3862727

Abstract Article PDF–256K

Select item 382700113.

c-KIT signaling is targeted by pathogenic Yersinia to suppress the host immune response

Sofiya N Micheva-Viteva, Yulin Shou, Kristy L Nowak-Lovato, Kirk D Rector, Elizabeth Hong-Geller

BMC Microbiol. 2013; 13: 249. Published online 2013 Nov 9. doi: 10.1186/1471-2180-13-249

PMCID:: PMC3827001

Abstract Article PDF–1.0M

Select item 376696914.

NF-?B-inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action

Liang Sheng, Yingjiang Zhou, Zheng Chen, Decheng Ren, Kae Won Cho, Lin Jiang, Hong Shen, Yoshiteru Sasaki, Liangyou Rui

Nat Med. Author manuscript; available in PMC 2013 Sep 9.

Published in final edited form as: Nat Med. 2012 Jun; 18(6): 943–949. doi: 10.1038/nm.2756

PMCID:: PMC3766969

Abstract Article PDF–2.3M

Select item 372391015.

A Network Integration Approach to Predict Conserved Regulators Related to Pathogenicity of Influenza and SARS-CoV Respiratory Viruses

Hugh D. Mitchell, Amie J. Eisfeld, Amy C. Sims, Jason E. McDermott, Melissa M. Matzke, Bobbi-Jo M. Webb-Robertson, Susan C. Tilton, Nicolas Tchitchek, Laurence Josset, Chengjun Li, Amy L. Ellis, Jean H. Chang, Robert A. Heegel, Maria L. Luna, Athena A. Schepmoes, Anil K. Shukla, Thomas O. Metz, Gabriele Neumann, Arndt G. Benecke, Richard D. Smith, Ralph S. Baric, Yoshihiro Kawaoka, Michael G. Katze, Katrina M. Waters

PLoS One. 2013; 8(7): e69374. Published online 2013 Jul 25. doi: 10.1371/journal.pone.0069374

PMCID:: PMC3723910

Abstract Article PDF–2.1M

Select item 353676816.

Downregulation of TRAF2 Mediates NIK-Induced Pancreatic Cancer Cell Proliferation and Tumorigenicity

Heike Döppler, Geou-Yarh Liou, Peter Storz

PLoS One. 2013; 8(1): e53676. Published online 2013 Jan 3. doi: 10.1371/journal.pone.0053676

PMCID:: PMC3536768

Abstract Article PDF–1.5M

Select item 284295317.

Heterogeneous, Longitudinally-Stable Molecular Signatures in Response to Interferon-β

M. R. Sandhya Rani, Yaomin Xu, Jar-chi Lee, Jennifer Shrock, Anupama Josyula, Joerg Schlaak, Swathi Chakraborthy, Nie Ja, Richard M. Ransohoff, Richard A. Rudick

Ann N Y Acad Sci. Author manuscript; available in PMC 2010 Mar 22.

Published in final edited form as: Ann N Y Acad Sci. 2009 Dec; 1182: 58–68. doi: 10.1111/j.1749-6632.2009.05068.x

PMCID:: PMC2842953

Abstract Article PDF–1.9M

Select item 273050918.

Frequent engagement of the classical and alternative NF-κB pathways by diverse genetic abnormalities in multiple myeloma

Christina M. Annunziata, R. Eric Davis, Yulia Demchenko, William Bellamy, Ana Gabrea, Fenghuang Zhan, Georg Lenz, Ichiro Hanamura, George Wright, Wenming Xiao, Sandeep Dave, Elaine M. Hurt, Bruce Tan, Hong Zhao, Owen Stephens, Madhumita Santra, David R. Williams, Lenny Dang, Bart Barlogie, John D. Shaughnessy, Jr, W. Michael Kuehl, Louis M. Staudt

Cancer Cell. Author manuscript; available in PMC 2009 Aug 23.

Published in final edited form as: Cancer Cell. 2007 Aug; 12(2): 115–130. doi: 10.1016/j.ccr.2007.07.004

PMCID:: PMC2730509

Abstract Article PDF–2.7M

Select item 267096919.

Phenanthrene-based tylophorine-1 (PBT-1) inhibits lung cancer cell growth through the Akt and NF-κB pathways

Jau-Chen Lin, Shuenn-Chen Yang, Tse-Ming Hong, Sung-Liang Yu, Qian Shi, Linyi Wei, Hsuan-Yu Chen, Pan-Chyr Yang, Kuo-Hsiung Lee

J Med Chem. Author manuscript; available in PMC 2010 Apr 9.

Published in final edited form as: J Med Chem. 2009 Apr 9; 52(7): 1903–1911. doi: 10.1021/jm801344j

PMCID:: PMC2670969

Abstract Article PDF–2.9M

Select item 266874120.

miRNA expression profiles in head and neck squamous cell carcinoma and adjacent normal tissue

Latha Ramdas, Uma Giri, Cheryl Ashorn, Kevin R. Coombes, Adel el-Naggar, K. Kian Ang, Michael D. Story

Head Neck. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Head Neck. 2009 May; 31(5): 642–654. doi: 10.1002/hed.21017

PMCID:: PMC2668741

Abstract Article PDF–1.0M

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