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Select item 61752231.

In Vivo Assessment of the Effect of CYP1A2 Inhibition and Induction on Pomalidomide Pharmacokinetics in Healthy Subjects

Yan Li, Liangang Liu, Xiaomin Wang, Chengyue Zhang, Josephine Reyes, Matthew Hoffmann, Maria Palmisano, Simon Zhou

J Clin Pharmacol. 2018 Oct; 58(10): 1295–1304. Published online 2018 May 15. doi: 10.1002/jcph.1145

PMCID:: PMC6175223

Abstract Article PDF–509K

Select item 59059972.

The CYP1A2 -163C>A polymorphism does not alter the effects of caffeine on basketball performance

Carlos Puente, Javier Abián-Vicén, Juan Del Coso, Beatriz Lara, Juan José Salinero

PLoS One. 2018; 13(4): e0195943. Published online 2018 Apr 18. doi: 10.1371/journal.pone.0195943

PMCID:: PMC5905997

Abstract Article PDF–1.4M

Select item 2981373.

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.

M A Butler, M Iwasaki, F P Guengerich, F F Kadlubar

Proc Natl Acad Sci U S A. 1989 Oct; 86(20): 7696–7700. doi: 10.1073/pnas.86.20.7696

PMCID:: PMC298137

Summary Page Browse PDF–1.1M

Select item 68303304.

Mesenchymal Stem Cells in the Adult Human Liver: Hype or Hope?

Irina V. Kholodenko, Leonid K. Kurbatov, Roman V. Kholodenko, Garik V. Manukyan, Konstantin N. Yarygin

Cells. 2019 Oct; 8(10): 1127. Published online 2019 Sep 22. doi: 10.3390/cells8101127

PMCID:: PMC6830330

Abstract Article PDF–1.7M

Select item 68264225.

The Selection and Validation of Reference Genes for mRNA and microRNA Expression Studies in Human Liver Slices Using RT-qPCR

Tomáš Zárybnický, Petra Matoušková, Martin Ambrož, Zdeněk Šubrt, Lenka Skálová, Iva Boušová

Genes (Basel) 2019 Oct; 10(10): 763. Published online 2019 Sep 28. doi: 10.3390/genes10100763

PMCID:: PMC6826422

Abstract Article PDF–1.7M

Select item 63003666.

Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells

Barbara Strojny, Ewa Sawosz, Marta Grodzik, Sławomir Jaworski, Jarosław Szczepaniak, Malwina Sosnowska, Mateusz Wierzbicki, Marta Kutwin, Sylwia Orlińska, André Chwalibog

Int J Nanomedicine. 2018; 13: 8561–8575. Published online 2018 Dec 13. doi: 10.2147/IJN.S188997

PMCID:: PMC6300366

Abstract Article PDF–5.0M

Select item 59588147.

Bacillus Calmette-Guérin induces rapid gene expression changes in human bladder cancer cell lines that may modulate its survival

Juwita N. Rahmat, Kesavan Esuvaranathan, Ratha Mahendran

Oncol Lett. 2018 Jun; 15(6): 9231–9241. Published online 2018 Apr 11. doi: 10.3892/ol.2018.8462

PMCID:: PMC5958814

Abstract Article PDF–1.0M

Select item 56896118.

A hemoglobin-based oxygen carrier sensitized Cisplatin based chemotherapy in hepatocellular carcinoma

Xiang Qi, Bing L. Wong, Sze Hang Lau, Kevin Tak-Pan Ng, Sui Yi Kwok, Chris Kin-Wai Sun, Fei Chuen Tzang, Yan Shao, Chang Xian Li, Wei Geng, Chang Chun Ling, Yuen Yuen Ma, Xiao Bing Liu, Hui Liu, Jiang Liu, Wai Ho Yeung, Chung Mau Lo, Kwan Man

Oncotarget. 2017 Oct 17; 8(49): 85311–85325. Published online 2017 Jul 28. doi: 10.18632/oncotarget.19672

PMCID:: PMC5689611

Abstract Article PDF–9.8M

Select item 53958569.

Autologous bone marrow-derived cell transplantation in decompensated alcoholic liver disease: what is the impact on liver histology and gene expression patterns?

Nicolas Lanthier, Nathalie Lin-Marq, Laura Rubbia-Brandt, Sophie Clément, Nicolas Goossens, Laurent Spahr

Stem Cell Res Ther. 2017; 8: 88. Published online 2017 Apr 18. doi: 10.1186/s13287-017-0541-2

PMCID:: PMC5395856

Abstract Article PDF–773K

Select item 499226110.

2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer

Lora J. Rogers, Alexei G. Basnakian, Mohammed S. Orloff, Baitang Ning, Aiwei Yao-Borengasser, Vinay Raj, Susan Kadlubar

Nutr Metab (Lond) 2016; 13: 54. Published online 2016 Aug 20. doi: 10.1186/s12986-016-0111-0

PMCID:: PMC4992261

Abstract Article PDF–1.4M

Select item 482171811.

Selective suppression of the human aryl hydrocarbon receptor function can be mediated through binding interference at the C-terminal half of the receptor

Lina Ren, John D. Thompson, Michael Cheung, Katherine Ngo, Sarah Sung, Scott Leong, William K. Chan

Biochem Pharmacol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Biochem Pharmacol. 2016 May 1; 107: 91–100. Published online 2016 Mar 9. doi: 10.1016/j.bcp.2016.03.004

PMCID:: PMC4821718

Abstract Article PDF–3.9M

Select item 470377312.

An Expanded Analysis of Pharmacogenetics Determinants of Efavirenz Response that Includes 3′-UTR Single Nucleotide Polymorphisms among Black South African HIV/AIDS Patients

Marelize Swart, Jonathan Evans, Michelle Skelton, Sandra Castel, Lubbe Wiesner, Peter J. Smith, Collet Dandara

Front Genet. 2015; 6: 356. Published online 2016 Jan 7. doi: 10.3389/fgene.2015.00356

PMCID:: PMC4703773

Abstract Article PDF–2.4M

Select item 430872813.

In silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genes

Anuradha Ramamoorthy, Todd C. Skaar

Drug Metab Lett. Author manuscript; available in PMC 2015 Jan 28.

Published in final edited form as: Drug Metab Lett. 2011 Apr; 5(2): 126–131. doi: 10.2174/187231211795305258

PMCID:: PMC4308728

Abstract Article PDF–466K

Select item 430436514.

Comprehensive Exploration of Novel Chimeric Transcripts in Clear Cell Renal Cell Carcinomas Using Whole Transcriptome Analysis

Masahiro Gotoh, Hitoshi Ichikawa, Eri Arai, Suenori Chiku, Hiromi Sakamoto, Hiroyuki Fujimoto, Masaki Hiramoto, Takao Nammo, Kazuki Yasuda, Teruhiko Yoshida, Yae Kanai

Genes Chromosomes Cancer. 2014 Dec; 53(12): 1018–1032. Published online 2014 Sep 18. doi: 10.1002/gcc.22211