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Select item 67356821.

XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence

Shuai Hou, Dajun Qu, Yue Li, Baohui Zhu, Dapeng Liang, Xinyue Wei, Wei Tang, Qian Zhang, Jiaojiao Hao, Wei Guo, Weijie Wang, Siqi Zhao, Qi Wang, Sikandar Azam, Misbah Khan, Haidong Zhao, Liye Zhang, Haixin Lei

Nucleic Acids Res. 2019 Sep 5; 47(15): 8239–8254. Published online 2019 Jun 19. doi: 10.1093/nar/gkz532

PMCID:: PMC6735682

Abstract Article PDF–8.1M

Select item 67154032.

Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb

Joshua E Mayfield, Seema Irani, Edwin E Escobar, Zhao Zhang, Nathaniel T Burkholder, Michelle R Robinson, M Rachel Mehaffey, Sarah N Sipe, Wanjie Yang, Nicholas A Prescott, Karan R Kathuria, Zhijie Liu, Jennifer S Brodbelt, Yan Zhang

eLife. 2019; 8: e48725. Published online 2019 Aug 6. doi: 10.7554/eLife.48725

PMCID:: PMC6715403

Abstract Article PDF–5.0M

Select item 65824093.

PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription

Nicole Steinbach, Dan Hasson, Deepti Mathur, Elias E Stratikopoulos, Ravi Sachidanandam, Emily Bernstein, Ramon E Parsons

Nucleic Acids Res. 2019 Jun 20; 47(11): 5573–5586. Published online 2019 Apr 24. doi: 10.1093/nar/gkz272

PMCID:: PMC6582409

Abstract Article PDF–5.8M

Select item 3120374.

Complete sequence of the human RNA polymerase II largest subunit.

M Wintzerith, J Acker, S Vicaire, M Vigneron, C Kedinger

Nucleic Acids Res. 1992 Feb 25; 20(4): 910. doi: 10.1093/nar/20.4.910

PMCID:: PMC312037

Summary Page Browse PDF–243K

Select item 64292785.

Role of Norepinephrine in IL-1β-Induced Chondrocyte Dedifferentiation under Physioxia

Saskia Speichert, Natalie Molotkov, Karima El Bagdadi, Andrea Meurer, Frank Zaucke, Zsuzsa Jenei-Lanzl

Int J Mol Sci. 2019 Mar; 20(5): 1212. Published online 2019 Mar 11. doi: 10.3390/ijms20051212

PMCID:: PMC6429278

Abstract Article PDF–5.5M

Select item 61612016.

ACTB and SDHA Are Suitable Endogenous Reference Genes for Gene Expression Studies in Human Astrocytomas Using Quantitative RT-PCR

Gabriele Röhn, Arend Koch, Boris Krischek, Pantelis Stavrinou, Roland Goldbrunner, Marco Timmer

Technol Cancer Res Treat. 2018; 17: 1533033818802318. Published online 2018 Sep 27. doi: 10.1177/1533033818802318

PMCID:: PMC6161201

Abstract Article PDF–491K

Select item 61075227.

CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

Melvin Noe Gonzalez, Shigeo Sato, Chieri Tomomori-Sato, Joan W. Conaway, Ronald C. Conaway

Nat Commun. 2018; 9: 3392. Published online 2018 Aug 23. doi: 10.1038/s41467-018-05923-w

PMCID:: PMC6107522

Abstract Article PDF–1.7M

Select item 60460878.

A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity

Xiao Zhou, Kim S. Friedmann, Hélène Lyrmann, Yan Zhou, Rouven Schoppmeyer, Arne Knörck, Sebastian Mang, Cora Hoxha, Adrian Angenendt, Christian S. Backes, Carmen Mangerich, Renping Zhao, Sabrina Cappello, Gertrud Schwär, Carmen Hässig, Marc Neef, Bernd Bufe, Frank Zufall, Karsten Kruse, Barbara A. Niemeyer, Annette Lis, Bin Qu, Carsten Kummerow, Eva C. Schwarz, Markus Hoth

J Physiol. 2018 Jul 15; 596(14): 2681–2698. Published online 2018 Mar 12. doi: 10.1113/JP274964

PMCID:: PMC6046087

Abstract Article PDF–1009K

Select item 58733629.

Air pollution-induced placental epigenetic alterations in early life: a candidate miRNA approach

Maria Tsamou, Karen Vrijens, Narjes Madhloum, Wouter Lefebvre, Charlotte Vanpoucke, Tim S Nawrot

Epigenetics. 2018; 13(2): 135–146. Published online 2018 Mar 5. doi: 10.1080/15592294.2016.1155012

PMCID:: PMC5873362

Abstract Article PDF–975K

Select item 557920910.

Stability of gene expression in human T cells in different gravity environments is clustered in chromosomal region 11p15.4

Cora S. Thiel, Andreas Huge, Swantje Hauschild, Svantje Tauber, Beatrice A. Lauber, Jennifer Polzer, Katrin Paulsen, Hartwin Lier, Frank Engelmann, Burkhard Schmitz, Andreas Schütte, Liliana E. Layer, Oliver Ullrich

NPJ Microgravity. 2017; 3: 22. Published online 2017 Aug 31. doi: 10.1038/s41526-017-0028-6

PMCID:: PMC5579209

Abstract Article PDF–3.3M

Select item 476148311.

Dephosphorylating Eukaryotic RNA Polymerase II

Joshua E. Mayfield, Nathaniel T. Burkholder, Yan Jessie Zhang

Biochim Biophys Acta. Author manuscript; available in PMC 2017 Apr 1.

Published in final edited form as: Biochim Biophys Acta. 2016 Apr; 1864(4): 372–387. Published online 2016 Jan 15. doi: 10.1016/j.bbapap.2016.01.007

PMCID:: PMC4761483

Abstract Article PDF–1.4M

Select item 474718812.

Transient receptor potential melastatin 4 channel contributes to migration of androgen-insensitive prostate cancer cells

Christian Holzmann, Sven Kappel, Tatiana Kilch, Marcus Martin Jochum, Sabine Katharina Urban, Volker Jung, Michael Stöckle, Karen Rother, Markus Greiner, Christine Peinelt

Oncotarget. 2015 Dec 8; 6(39): 41783–41793. Published online 2015 Oct 19. doi: 10.18632/oncotarget.6157

PMCID:: PMC4747188

Abstract Article PDF–2.6M

Select item 460109013.

Differential Redox Regulation of Ca²⁺ Signaling and Viability in Normal and Malignant Prostate Cells

Christian Holzmann, Tatiana Kilch, Sven Kappel, Kathrin Dörr, Volker Jung, Michael Stöckle, Ivan Bogeski, Christine Peinelt

Biophys J. 2015 Oct 6; 109(7): 1410–1419. Published online 2015 Oct 6. doi: 10.1016/j.bpj.2015.08.006

PMCID:: PMC4601090

Abstract Article PDF–1.0M

Select item 449658514.

ONTOGENIC EXPRESSION OF HUMAN CARBOXYLESTERASE-2 AND CYTOCHROME P450 3A4 IN LIVER AND DUODENUM: POSTNATAL SURGE AND ORGAN-DEPENDENT REGULATION

Yi-Tzai Chen, Lynnie Trzoss, Dongfang Yang, Bingfang Yan

Toxicology. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Toxicology. 2015 Apr 1; 330: 55–61. Published online 2015 Feb 24. doi: 10.1016/j.tox.2015.02.007

PMCID:: PMC4496585

Abstract Article PDF–522K

Select item 430049915.

Angiogenin Secretion From Hepatoma Cells Activates Hepatic Stellate Cells To Amplify A Self-Sustained Cycle Promoting Liver Cancer

Cristina Bárcena, Milica Stefanovic, Anna Tutusaus, Guillermo A. Martinez-Nieto, Laura Martinez, Carmen García-Ruiz, Alvaro de Mingo, Juan Caballeria, José C. Fernandez-Checa, Montserrat Marí, Albert Morales

Sci Rep. 2015; 5: 7916. Published online 2015 Jan 21. doi: 10.1038/srep07916

PMCID:: PMC4300499

Abstract Article PDF–1.4M

Select item 427227716.

Reference Gene Selection for qPCR Is Dependent on Cell Type Rather than Treatment in Colonic and Vaginal Human Epithelial Cell Lines

Annette V. Jacobsen, Bisrat T. Yemaneab, Jana Jass, Nikolai Scherbak

PLoS One. 2014; 9(12): e115592. Published online 2014 Dec 19. doi: 10.1371/journal.pone.0115592

PMCID:: PMC4272277

Abstract Article PDF–997K

Select item 425620117.

Identification of Optimal Reference Genes for Gene Expression Normalization in a Wide Cohort of Endometrioid Endometrial Carcinoma Tissues

Chiara Romani, Stefano Calza, Paola Todeschini, Renata A. Tassi, Laura Zanotti, Elisabetta Bandiera, Enrico Sartori, Sergio Pecorelli, Antonella Ravaggi, Alessandro D. Santin, Eliana Bignotti

PLoS One. 2014; 9(12): e113781. Published online 2014 Dec 4. doi: 10.1371/journal.pone.0113781