PMC Links for Nucleotide (Select 1519244705) - PMC

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Select item 68318511.

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis

Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu

iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057

PMCID:: PMC6831851

Abstract Article PDF–9.8M

Select item 66945152.

Temporal integration of mitochondrial stress signals by the PINK1:Parkin pathway

J. Logan Bowling, Mary Catherine Skolfield, Wesley A. Riley, Andrew P. Nolin, Larissa C. Wolf, David E. Nelson

BMC Mol Cell Biol. 2019; 20: 33. Published online 2019 Aug 14. doi: 10.1186/s12860-019-0220-5

PMCID:: PMC6694515

Abstract Article PDF–9.4M

Select item 65537793.

PINK1 attenuates mtDNA release in alveolar epithelial cells and TLR9 mediated profibrotic responses

Marta Bueno, Daniel Zank, Ivette Buendia-Roldán, Kaitlin Fiedler, Brenton G. Mays, Diana Alvarez, John Sembrat, Brian Kimball, Jordan K. Bullock, James L. Martin, Mehdi Nouraie, Brett A. Kaufman, Mauricio Rojas, Annie Pardo, Moisés Selman, Ana L. Mora

PLoS One. 2019; 14(6): e0218003. Published online 2019 Jun 6. doi: 10.1371/journal.pone.0218003

PMCID:: PMC6553779

Abstract Article PDF–2.0M

Select item 63959454.

Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice

Hua Wang, Hong-Min Ni, Xiaojuan Chao, Xiaowen Ma, Yssa Ann Rodriguez, Hemantkumar Chavan, Shaogui Wang, Partha Krishnamurthy, Rick Dobrowsky, De-Xiang Xu, Hartmut Jaeschke, Wen-Xing Ding

Redox Biol. 2019 Apr; 22: 101148. Published online 2019 Feb 20. doi: 10.1016/j.redox.2019.101148

PMCID:: PMC6395945

Abstract Article PDF–4.6M

Select item 12756435.

Localization of a Novel Locus for Autosomal Recessive Early-Onset Parkinsonism, PARK6, on Human Chromosome 1p35-p36

Enza Maria Valente, Anna Rita Bentivoglio, Peter H. Dixon, Alessandro Ferraris, Tamara Ialongo, Marina Frontali, Alberto Albanese, and Nicholas W. Wood

Am J Hum Genet. 2001 Apr; 68(4): 895–900. Published online 2001 Mar 7. doi: 10.1086/319522

PMCID:: PMC1275643

Abstract Article PDF–235K

Select item 68371636.

The Role of Genetic Testing in the Clinical Practice and Research of Early-Onset Parkinsonian Disorders in a Hungarian Cohort: Increasing Challenge in Genetic Counselling, Improving Chances in Stratification for Clinical Trials

Anett Illés, Dóra Csabán, Zoltán Grosz, Péter Balicza, András Gézsi, Viktor Molnár, Renáta Bencsik, Anikó Gál, Péter Klivényi, Maria Judit Molnar

Front Genet. 2019; 10: 1061. Published online 2019 Oct 31. doi: 10.3389/fgene.2019.01061

PMCID:: PMC6837163

Abstract Article PDF–1.3M

Select item 66797747.

The AMPK-Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome

Seung Baek Lee, Jung Jin Kim, Sang-Ah Han, Yingfang Fan, Li-Sha Guo, Khaled Aziz, Somaira Nowsheen, Sung Sun Kim, Seon-Young Park, Qifeng Luo, Jin Ook Chung, Sung Il Choi, Asef Aziz, Ping Yin, Seo-Yun Tong, Fabienne C. Fiesel, Wolfdieter Springer, Jin-San Zhang, Zhenkun Lou

Nat Cell Biol. Author manuscript; available in PMC 2020 Jan 29.

Published in final edited form as: Nat Cell Biol. 2019 Aug; 21(8): 940–951. Published online 2019 Jul 29. doi: 10.1038/s41556-019-0356-8

PMCID:: PMC6679774

Abstract Article PDF–4.3M

Select item 62104218.

Epigenetic Study in Parkinson’s Disease: A Pilot Analysis of DNA Methylation in Candidate Genes in Brain

Luis Navarro-Sánchez, Beatriz Águeda-Gómez, Silvia Aparicio, Jordi Pérez-Tur

Cells. 2018 Oct; 7(10): 150. Published online 2018 Sep 26. doi: 10.3390/cells7100150

PMCID:: PMC6210421

Abstract Article PDF–268K

Select item 61744589.

Genetic Identification in Early Onset Parkinsonism among Norwegian Patients

Emil K. Gustavsson, Joanne Trinh, Marna McKenzie, Stephanie Bortnick, Maria Skaalum Petersen, Matthew J. Farrer, Jan O. Aasly

Mov Disord Clin Pract. 2017 Jul-Aug; 4(4): 499–508. Published online 2017 May 23. doi: 10.1002/mdc3.12501

PMCID:: PMC6174458

Abstract Article PDF–357K

Select item 535466410.

Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels

Guo-Bing Li, Ruo-Qiu Fu, Han-Ming Shen, Jing Zhou, Xiao-Ye Hu, Yan-Xia Liu, Yu-Nong Li, Hong-Wei Zhang, Xin Liu, Yan-Hao Zhang, Cheng Huang, Rong Zhang, Ning Gao

Oncotarget. 2017 Feb 7; 8(6): 10359–10374. Published online 2017 Jan 2. doi: 10.18632/oncotarget.14413

PMCID:: PMC5354664

Abstract Article PDF–16M

Select item 519624311.

The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1

Li Xiao, Xiaoxuan Xu, Fan Zhang, Ming Wang, Yan Xu, Dan Tang, Jiahui Wang, Yan Qin, Yu Liu, Chengyuan Tang, Liyu He, Anna Greka, Zhiguang Zhou, Fuyou Liu, Zheng Dong, Lin Sun

Redox Biol. 2017 Apr; 11: 297–311. Published online 2016 Dec 21. doi: 10.1016/j.redox.2016.12.022