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Select item 70045331.

Epidermal growth factor receptor mRNA expression: A potential molecular escape mechanism from regorafenib

Satoshi Matsusaka, Diana L. Hanna, Yan Ning, Dongyun Yang, Shu Cao, Martin D. Berger, Yuji Miyamoto, Mitsukuni Suenaga, Shingo Dan, Tetsuo Mashima, Hiroyuki Seimiya, Wu Zhang, Heinz‐Josef Lenz

Cancer Sci. 2020 Feb; 111(2): 441–450. Published online 2020 Jan 27. doi: 10.1111/cas.14273

PMCID:: PMC7004533

Abstract Article PDF–392K

Select item 1462042.

A 1.8 kb alternative transcript from the human epidermal growth factor receptor gene encodes a truncated form of the receptor.

J L Reiter, N J Maihle

Nucleic Acids Res. 1996 Oct 15; 24(20): 4050–4056. doi: 10.1093/nar/24.20.4050

PMCID:: PMC146204

Summary PDF–178K

Select item 69731153.

Variation in nomenclature of somatic variants for selection of oncological therapies: Can we reach a consensus soon?

Cleo Keppens, Véronique Tack, Kelly Dufraing, Etienne Rouleau, Marjolijn J. L. Ligtenberg, Ed Schuuring, Elisabeth M. C. Dequeker

Hum Mutat. 2020 Jan; 41(1): 7–16. Published online 2019 Oct 14. doi: 10.1002/humu.23926

PMCID:: PMC6973115

Abstract Article PDF–848K

Select item 69667094.

SEL1L plays a major role in human malignant gliomas

Marta Mellai, Laura Annovazzi, Renzo Boldorini, Luca Bertero, Paola Cassoni, Pasquale De Blasio, Ida Biunno, Davide Schiffer

J Pathol Clin Res. 2020 Jan; 6(1): 17–29. Published online 2019 Sep 30. doi: 10.1002/cjp2.134

PMCID:: PMC6966709

Abstract Article PDF–4.8M

Select item 69665295.

Standardization of Somatic Variant Classifications in Solid and Haematological Tumours by a Two-Level Approach of Biological and Clinical Classes: An Initiative of the Belgian ComPerMed Expert Panel

Guy Froyen, Marie Le Mercier, Els Lierman, Karl Vandepoele, Friedel Nollet, Elke Boone, Joni Van der Meulen, Koen Jacobs, Suzan Lambin, Sara Vander Borght, Els Van Valckenborgh, Aline Antoniou, Aline Hébrant

Cancers (Basel) 2019 Dec; 11(12): 2030. Published online 2019 Dec 16. doi: 10.3390/cancers11122030

PMCID:: PMC6966529

Abstract Article PDF–710K

Select item 69568216.

The combination of bevacizumab/Avastin and erlotinib/Tarceva is relevant for the treatment of metastatic renal cell carcinoma: the role of a synonymous mutation of the EGFR receptor

Renaud Grépin, Mélanie Guyot, Aurore Dumond, Jérôme Durivault, Damien Ambrosetti, Jean-François Roussel, Florence Dupré, Hervé Quintens, Gilles Pagès

Theranostics. 2020; 10(3): 1107–1121. Published online 2020 Jan 1. doi: 10.7150/thno.38346

PMCID:: PMC6956821

Abstract Article PDF–2.5M

Select item 69277737.

Inter-laboratory proficiency testing scheme for tumour next-generation sequencing in Ontario: a pilot study

T. Spence, N. Stickle, C. Yu, H. Chow, H. Feilotter, B. Lo, E. McCready, B. Sadikovic, L.L. Siu, P.L. Bedard, T.L. Stockley

Curr Oncol. 2019 Dec; 26(6): e717–e732. Published online 2019 Dec 1. doi: 10.3747/co.26.5379

PMCID:: PMC6927773

Abstract Article PDF–823K

Select item 68861268.

Targeting PKCδ as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer

Pei-Chih Lee, Yueh-Fu Fang, Hirohito Yamaguchi, Wei-Jan Wang, Tse-Ching Chen, Xuan Hong, Baozhen Ke, Weiya Xia, Yongkun Wei, Zhengyu Zha, Yan Wang, Han-Pin Kuo, Chih-Wei Wang, Chih-Yen Tu, Chia-Hung Chen, Wei-Chien Huang, Shu-Fen Chiang, Lei Nie, Junwei Hou, Chun-Te Chen, Longfei Huo, Wen-Hao Yang, Rong Deng, Katsuya Nakai, Yi-Hsin Hsu, Shih-Shin Chang, Tai-Jan Chiu, Jun Tang, Ran Zhang, Li Wang, Bingliang Fang, Ting Chen, Kwok-Kin Wong, Jennifer L. Hsu, Mien-Chie Hung

Cancer Cell. Author manuscript; available in PMC 2019 Dec 10.

Published in final edited form as: Cancer Cell. 2018 Dec 10; 34(6): 954–969.e4. doi: 10.1016/j.ccell.2018.11.007

PMCID:: PMC6886126

Abstract Article PDF–2.2M

Select item 68819059.

Rapid and ultrasensitive digital PCR (dPCR) profiling of EGFRvIII in tumor cells and tissues

Deeksha Saxena, Saad Sheikh, Gary Kao, Zev A Binder, Michelle Alonso-Basanta, Donald M O’Rourke, MacLean P Nasrallah, Jay F Dorsey

Neurooncol Adv. 2019 May-Dec; 1(1): vdz030. Published online 2019 Nov 28. doi: 10.1093/noajnl/vdz030

PMCID:: PMC6881905

Abstract Article PDF–1.5M

Select item 682813810.

Correction to: Identification of novel mutations in FFPE lung adenocarcinomas using DEPArray sorting technology and next-generation sequencing

Ji Won Lee, Jong-Yeon Shin, Jeong-Sun Seo

J Appl Genet. 2018; 59(3): 279–280. Published online 2018 Apr 24. doi: 10.1007/s13353-018-0442-9

Corrects:: J Appl Genet. 2018; 59(3): 269–277.

PMCID:: PMC6828138

Correction PDF–284K

Select item 673343211.

A linear polyethylenimine mediated siRNA-based therapy targeting human epidermal growth factor receptor in SPC-A1 xenograft mice

Pinghai Zhang, Nuo Xu, Lei Zhou, Xin Xu, Yuehong Wang, Ka Li, Zhaochong Zeng, Xiangdong Wang, Xin Zhang, Chunxue Bai

Transl Respir Med. 2013; 1: 2. Published online 2013 Feb 22. doi: 10.1186/2213-0802-1-2

PMCID:: PMC6733432

Abstract Article PDF–2.5M

Select item 669133512.

The DNA walk and its demonstration of deterministic chaos—relevance to genomic alterations in lung cancer

Blake Hewelt, Haiqing Li, Mohit Kumar Jolly, Prakash Kulkarni, Isa Mambetsariev, Ravi Salgia

Bioinformatics. 2019 Aug 15; 35(16): 2738–2748. Published online 2019 Jan 7. doi: 10.1093/bioinformatics/bty1021

PMCID:: PMC6691335

Abstract Article PDF–1.0M

Select item 665943913.

European mtDNA Variants Are Associated With Differential Responses to Cisplatin, an Anticancer Drug: Implications for Drug Resistance and Side Effects

Tej H. Patel, Lucas Norman, Steven Chang, Sina Abedi, Catherine Liu, Marilyn Chwa, Shari R. Atilano, Kunal Thaker, Stephanie Lu, S. Michal Jazwinski, Michael V. Miceli, Nitin Udar, Daniela Bota, M. Cristina Kenney

Front Oncol. 2019; 9: 640. Published online 2019 Jul 19. doi: 10.3389/fonc.2019.00640

PMCID:: PMC6659439

Abstract Article PDF–1.8M

Select item 662781214.

Design and Validation of a Gene-Targeted, Next-Generation Sequencing Panel for Routine Diagnosis in Gliomas

Nicky D’Haene, Bárbara Meléndez, Oriane Blanchard, Nancy De Nève, Laetitia Lebrun, Claude Van Campenhout, Isabelle Salmon

Cancers (Basel) 2019 Jun; 11(6): 773. Published online 2019 Jun 4. doi: 10.3390/cancers11060773

PMCID:: PMC6627812

Abstract Article PDF–1.2M

Select item 658563515.

Lentivirus‐mediated disintegrin and metalloproteinase 17 RNA interference reversed the acquired resistance to gefitinib in lung adenocarcinoma cells in vitro

Ya‐Qing Li, Yuan‐Shun Liu, Xi‐Wang Ying, Hong‐Bin Zhou, Zhehua Wang, Sheng‐Chang Wu, Jian‐Ping Yan, Yu‐Ting Jing, Yang Yang

Biotechnol Prog. 2018 Jan-Feb; 34(1): 196–205. Published online 2017 Oct 27. doi: 10.1002/btpr.2564

PMCID:: PMC6585635

Abstract Article PDF–939K

Select item 644301516.

Relationship between EGFR expression and subcellular localization with cancer development and clinical outcome

Ge Yan, Mohamed E.M. Saeed, Sebastian Foersch, Jose Schneider, Wilfried Roth, Thomas Efferth

Oncotarget. 2019 Mar 8; 10(20): 1918–1931. Published online 2019 Mar 8. doi: 10.18632/oncotarget.26727

PMCID:: PMC6443015

Abstract Article PDF–3.0M

Select item 638538917.

Glycerol kinase 5 confers gefitinib resistance through SREBP1/SCD1 signaling pathway

Jian Zhou, Guimei Qu, Ge Zhang, Zuoren Wu, Jing Liu, Dawei Yang, Jing Li, Meijia Chang, Hengshan Zeng, Jie Hu, Tao Fang, Yuanlin Song, Chunxue Bai

J Exp Clin Cancer Res. 2019; 38: 96. Published online 2019 Feb 21. doi: 10.1186/s13046-019-1057-7

PMCID:: PMC6385389

Abstract Article PDF–5.5M

Select item 612139518.

The Role of the Nuclear Factor κB Pathway in the Cellular Response to Low and High Linear Energy Transfer Radiation

Christine E. Hellweg, Luis F. Spitta, Kristina Koch, Arif A. Chishti, Bernd Henschenmacher, Sebastian Diegeler, Bikash Konda, Sebastian Feles, Claudia Schmitz, Thomas Berger, Christa Baumstark-Khan

Int J Mol Sci. 2018 Aug; 19(8): 2220. Published online 2018 Jul 30. doi: 10.3390/ijms19082220

PMCID:: PMC6121395

Abstract Article PDF–7.3M

Select item 611145719.

Calpain 2 knockdown promotes cell apoptosis and restores gefitinib sensitivity through epidermal growth factor receptor/protein kinase B/survivin signaling

Ge Zhang, Tao Fang, Meijia Chang, Jing Li, Qunying Hong, Chunxue Bai, Jian Zhou

Oncol Rep. 2018 Oct; 40(4): 1937–1946. Published online 2018 Aug 2. doi: 10.3892/or.2018.6625

PMCID:: PMC6111457

Abstract Article PDF–1.6M

Select item 606099420.

Identification of novel mutations in FFPE lung adenocarcinomas using DEPArray sorting technology and next-generation sequencing

Ji Won Lee, Jong-Yeon Shin, Jeong-Sun Seo

J Appl Genet. 2018; 59(3): 269–277. Published online 2018 Mar 10. doi: 10.1007/s13353-018-0439-4

Correction in:: J Appl Genet. 2018; 59(3): 279–280.

PMCID:: PMC6060994

Abstract Article PDF–1.9M

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