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Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 59147332.

UHRF1 epigenetically down-regulates UbcH8 to inhibit apoptosis in cervical cancer cells

Qishu Zhang, Lijun Qiao, Xiao Wang, Changkuan Ding, Jason J. Chen

Cell Cycle. 2018; 17(3): 300–308. Published online 2018 Jan 31. doi: 10.1080/15384101.2017.1403686

PMCID:: PMC5914733

Abstract Article PDF–1.1M

Select item 54103203.

UBE2L6/UBCH8 and ISG15 attenuate autophagy in esophageal cancer cells

Chloe M. Falvey, Tracey R. O'Donovan, Shereen El-Mashed, Michelle J. Nyhan, Seamus O'Reilly, Sharon L. McKenna

Oncotarget. 2017 Apr 4; 8(14): 23479–23491. Published online 2017 Feb 8. doi: 10.18632/oncotarget.15182

Correction in:: Oncotarget. 2020 Jan 14; 11(2): 212.

PMCID:: PMC5410320

Abstract Article PDF–11M

Select item 47473914.

Epigenetic downregulation of the ISG15–conjugating enzyme UbcH8 impairs lipolysis and correlates with poor prognosis in nasopharyngeal carcinoma

Xiaoying Zhou, Jiazhang Wei, Fu Chen, Xue Xiao, Tingting Huang, Qian He, Shumin Wang, Chunping Du, Yingxi Mo, Longde Lin, Ying Xie, Lili Wei, Ying Lan, Mairiko Murata, Guangwu Huang, Ingemar Ernberg, Liudmila Matskova, Zhe Zhang

Oncotarget. 2015 Dec 1; 6(38): 41077–41091. Published online 2015 Oct 12. doi: 10.18632/oncotarget.6218

PMCID:: PMC4747391

Abstract Article PDF–7.0M

Select item 54550995.

Ubiquitin-Proteasome-Collagen (CUP) Pathway in Preterm Premature Rupture of Fetal Membranes

Xinliang Zhao, Xiaoyan Dong, Xiucui Luo, Jing Pan, Weina Ju, Meijiao Zhang, Peirong Wang, Mei Zhong, Yanhong Yu, W. Ted Brown, Nanbert Zhong

Front Pharmacol. 2017; 8: 310. Published online 2017 Jun 2. doi: 10.3389/fphar.2017.00310

PMCID:: PMC5455099

Abstract Article PDF–1.4M

Select item 50419826.

Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma

Uddalak Bharadwaj, T. Kris Eckols, Xuejun Xu, Moses M. Kasembeli, Yunyun Chen, Makoto Adachi, Yongcheng Song, Qianxing Mo, Stephen Y. Lai, David J. Tweardy

Oncotarget. 2016 May 3; 7(18): 26307–26330. Published online 2016 Mar 25. doi: 10.18632/oncotarget.8368

Correction in:: Oncotarget. 2019 Feb 22; 10(16): 1603.

PMCID:: PMC5041982

Abstract Article PDF–5.8M

Select item 35287437.

In Silico Target-Specific siRNA Design Based on Domain Transfer in Heterogeneous Data

Qi Liu, Han Zhou, Kui Zhang, Xiaoxiao Shi, Wei Fan, Ruixin Zhu, Philip S. Yu, Zhiwei Cao

PLoS One. 2012; 7(12): e50697. Published online 2012 Dec 21. doi: 10.1371/journal.pone.0050697

PMCID:: PMC3528743

Abstract Article PDF–1.0M

Select item 34129658.

A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen

Yi Sheng, Jenny H. Hong, Ryan Doherty, Tharan Srikumar, Jonathan Shloush, George V. Avvakumov, John R. Walker, Sheng Xue, Dante Neculai, Janet W. Wan, Sung K. Kim, Cheryl H. Arrowsmith, Brian Raught, Sirano Dhe-Paganon

Mol Cell Proteomics. 2012 Aug; 11(8): 329–341. Published online 2012 Apr 10. doi: 10.1074/mcp.O111.013706

PMCID:: PMC3412965

Abstract Article PDF–2.4M

Select item 33689019.

Selective Hyper-responsiveness of the Interferon System in Major Depressive Disorders and Depression Induced by Interferon Therapy

Joerg F. Schlaak, Martin Trippler, Carolina Hoyo-Becerra, Yesim Erim, Bernhard Kis, Bo Wang, Norbert Scherbaum, Guido Gerken

PLoS One. 2012; 7(6): e38668. Published online 2012 Jun 6. doi: 10.1371/journal.pone.0038668

PMCID:: PMC3368901

Abstract Article PDF–883K

Select item 331884810.

Interaction of Bifidobacterium bifidum LMG13195 with HT29 Cells Influences Regulatory-T-Cell-Associated Chemokine Receptor Expression

Patricia López, Irene González-Rodríguez, Borja Sánchez, Patricia Ruas-Madiedo, Ana Suárez, Abelardo Margolles, Miguel Gueimonde

Appl Environ Microbiol. 2012 Apr; 78(8): 2850–2857. doi: 10.1128/AEM.07581-11

PMCID:: PMC3318848

Abstract Article PDF–862K

Select item 319283811.

Hepatitis C Virus Reveals a Novel Early Control in Acute Immune Response

Noëlla Arnaud, Stéphanie Dabo, Daisuke Akazawa, Masayoshi Fukasawa, Fumiko Shinkai-Ouchi, Jacques Hugon, Takaji Wakita, Eliane F. Meurs

PLoS Pathog. 2011 Oct; 7(10): e1002289. Published online 2011 Oct 13. doi: 10.1371/journal.ppat.1002289

PMCID:: PMC3192838

Abstract Article PDF–2.1M

Select item 314760012.

Selective Ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G Ubiquitin-Conjugating Enzymes via the CRL4^Cdt2 Ubiquitin Ligase Complex

Etsuko Shibata, Tarek Abbas, Xinhua Huang, James A. Wohlschlegel, Anindya Dutta

Mol Cell Biol. 2011 Aug; 31(15): 3136–3145. doi: 10.1128/MCB.05496-11

PMCID:: PMC3147600

Abstract Article PDF–1.3M

Select item 313952013.

CD4⁺ T-Cell Decline after the Interruption of Antiretroviral Therapy in ACTG A5170 Is Predicted by Differential Expression of Genes in the Ras Signaling Pathway

Maryanne T. Vahey, Zhining Wang, Zhaohui Su, Martin E. Nau, Amy Krambrink, Daniel J. Skiest, David M. Margolis

AIDS Res Hum Retroviruses. 2008 Aug; 24(8): 1047–1066. doi: 10.1089/aid.2008.0059

PMCID:: PMC3139520

Abstract Article PDF–782K

Select item 308598614.

Down-regulation of UCRP and UBE2L6 in BRCA2 knocked-down human breast cells

Manish K. Tripathi, Gautam Chaudhuri

Biochem Biophys Res Commun. Author manuscript; available in PMC 2011 May 3.

Published in final edited form as: Biochem Biophys Res Commun. 2005 Mar 4; 328(1): 43–48. doi: 10.1016/j.bbrc.2004.12.142

PMCID:: PMC3085986

Abstract Article PDF–423K

Select item 301999815.

Indoleamine 2,3-Dioxygenase Mediates the Antiviral Effect of Gamma Interferon against Hepatitis B Virus in Human Hepatocyte-Derived Cells

Richeng Mao, Jiming Zhang, Dong Jiang, Dawei Cai, Jessica M. Levy, Andrea Cuconati, Timothy M. Block, Ju-Tao Guo, Haitao Guo

J Virol. 2011 Jan; 85(2): 1048–1057. Published online 2010 Nov 17. doi: 10.1128/JVI.01998-10

PMCID:: PMC3019998

Abstract Article PDF–1.5M

Select item 301777916.

Gene expression profiling in the lungs of pigs with different susceptibilities to Glässer's disease

Jamie M Wilkinson, Carole A Sargent, Lucina Galina-Pantoja, Alexander W Tucker

BMC Genomics. 2010; 11: 455. Published online 2010 Jul 29. doi: 10.1186/1471-2164-11-455

PMCID:: PMC3017779

Abstract Article PDF–1.4M

Select item 295057817.

Identification of Alpha Interferon-Induced Genes Associated with Antiviral Activity in Daudi Cells and Characterization of IFIT3 as a Novel Antiviral Gene

H. Schmeisser, J. Mejido, C. A. Balinsky, A. N. Morrow, C. R. Clark, T. Zhao, K. C. Zoon

J Virol. 2010 Oct; 84(20): 10671–10680. Published online 2010 Aug 4. doi: 10.1128/JVI.00818-10

PMCID:: PMC2950578

Abstract Article PDF–1.1M

Select item 291651718.

Identification of Five Interferon-Induced Cellular Proteins That Inhibit West Nile Virus and Dengue Virus Infections

Dong Jiang, Jessica M. Weidner, Min Qing, Xiao-Ben Pan, Haitao Guo, Chunxiao Xu, Xianchao Zhang, Alex Birk, Jinhong Chang, Pei-Yong Shi, Timothy M. Block, Ju-Tao Guo

J Virol. 2010 Aug; 84(16): 8332–8341. Published online 2010 Jun 9. doi: 10.1128/JVI.02199-09

PMCID:: PMC2916517

Abstract Article PDF–1.8M

Select item 287563919.

Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment

Lisa GM van Baarsen, Carla A Wijbrandts, François Rustenburg, Tineke Cantaert, Tineke CTM van der Pouw Kraan, Dominique L Baeten, Ben AC Dijkmans, Paul P Tak, Cornelis L Verweij

Arthritis Res Ther. 2010; 12(1): R11. Published online 2010 Jan 22. doi: 10.1186/ar2912

PMCID:: PMC2875639

Abstract Article PDF–681K

Select item 284295320.

Heterogeneous, Longitudinally-Stable Molecular Signatures in Response to Interferon-β

M. R. Sandhya Rani, Yaomin Xu, Jar-chi Lee, Jennifer Shrock, Anupama Josyula, Joerg Schlaak, Swathi Chakraborthy, Nie Ja, Richard M. Ransohoff, Richard A. Rudick

Ann N Y Acad Sci. Author manuscript; available in PMC 2010 Mar 22.

Published in final edited form as: Ann N Y Acad Sci. 2009 Dec; 1182: 58–68. doi: 10.1111/j.1749-6632.2009.05068.x