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Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 45024162.

Classical Nuclear Localization Signals: Definition, Function, and Interaction with Importin α

Allison Lange, Ryan E. Mills, Christopher J. Lange, Murray Stewart, Scott E. Devine, Anita H. Corbett

J Biol Chem. Author manuscript; available in PMC 2015 Jul 15.

Published in final edited form as: J Biol Chem. 2007 Feb 23; 282(8): 5101–5105. Published online 2006 Dec 14. doi: 10.1074/jbc.R600026200

PMCID:: PMC4502416

Abstract Article PDF–554K

Select item 21328423.

Determination of the Functional Domain Organization of the Importin α Nuclear Import Factor

Andrea Herold, Ray Truant, Heather Wiegand, Bryan R. Cullen

J Cell Biol. 1998 Oct 19; 143(2): 309–318. doi: 10.1083/jcb.143.2.309

PMCID:: PMC2132842

Abstract Article PDF–377K

Select item 4500984.

The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import.

K Weis, U Ryder, A I Lamond

EMBO J. 1996 Apr 15; 15(8): 1818–1825.

PMCID:: PMC450098

Summary Page Browse PDF–1.9M

Select item 495455.

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes.

M I Bukrinsky, N Sharova, M P Dempsey, T L Stanwick, A G Bukrinskaya, S Haggerty, M Stevenson

Proc Natl Acad Sci U S A. 1992 Jul 15; 89(14): 6580–6584. doi: 10.1073/pnas.89.14.6580

PMCID:: PMC49545

Summary Page Browse PDF–1.4M

Select item 441576.

Rch1, a protein that specifically interacts with the RAG-1 recombination-activating protein.

C A Cuomo, S A Kirch, J Gyuris, R Brent, M A Oettinger

Proc Natl Acad Sci U S A. 1994 Jun 21; 91(13): 6156–6160. doi: 10.1073/pnas.91.13.6156

PMCID:: PMC44157

Summary Page Browse PDF–1.2M

Select item 415527.

Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins.

J Moroianu, M Hijikata, G Blobel, A Radu

Proc Natl Acad Sci U S A. 1995 Jul 3; 92(14): 6532–6536. doi: 10.1073/pnas.92.14.6532

PMCID:: PMC41552

Summary Page Browse PDF–1.4M

Select item 60438228.

Early Transcriptional Events During Osteogenic Differentiation of Human Bone Marrow Stromal Cells Induced by Lim Mineralization Protein 3

Camilla Bernardini, Nathalie Saulnier, Claudio Parrilla, Enrico Pola, Andrea Gambotto, Fabrizio Michetti, Paul D. Robbins, Wanda Lattanzi

Gene Expr. 2010; 15(1): 27–42. Published online 2018 Jul 13. doi: 10.3727/105221610x12819686555097

PMCID:: PMC6043822

Abstract Article PDF–6.6M

Select item 55255849.

Hard clam extracts induce atypical apoptosis in human gastric cancer cells

Eing-Ju Song, Michael W.Y. Chan, Jyh-Wei Shin, Che-Chun Chen

Exp Ther Med. 2017 Aug; 14(2): 1409–1418. Published online 2017 Jun 20. doi: 10.3892/etm.2017.4630

PMCID:: PMC5525584

Abstract Article PDF–1.3M

Select item 537675510.

Gene expression profiling of patient‐derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts

Benjamin Bian, Martin Bigonnet, Odile Gayet, Celine Loncle, Aurélie Maignan, Marine Gilabert, Vincent Moutardier, Stephane Garcia, Olivier Turrini, Jean‐Robert Delpero, Marc Giovannini, Philippe Grandval, Mohamed Gasmi, Mehdi Ouaissi, Veronique Secq, Flora Poizat, Rémy Nicolle, Yuna Blum, Laetitia Marisa, Marion Rubis, Jean‐Luc Raoul, James E Bradner, Jun Qi, Gwen Lomberk, Raul Urrutia, Andres Saul, Nelson Dusetti, Juan Iovanna

EMBO Mol Med. 2017 Apr; 9(4): 482–497. Published online 2017 Mar 8. doi: 10.15252/emmm.201606975

PMCID:: PMC5376755

Abstract Article PDF–1.4M

Select item 481405011.

Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station

Masahiro Terada, Masaya Seki, Rika Takahashi, Shin Yamada, Akira Higashibata, Hideyuki J. Majima, Masamichi Sudoh, Chiaki Mukai, Noriaki Ishioka

PLoS One. 2016; 11(3): e0150801. Published online 2016 Mar 30. doi: 10.1371/journal.pone.0150801

Correction in:: PLoS One. 2016; 11(5): e0156190.

PMCID:: PMC4814050

Abstract Article PDF–1.7M

Select item 469515212.

MiR-26b/KPNA2 axis inhibits epithelial ovarian carcinoma proliferation and metastasis through downregulating OCT4

Jiaxin Lin, Lan Zhang, He Huang, Yongwen Huang, Long Huang, Jianhua Wang, Shuting Huang, Li He, Yun Zhou, Weihua Jia, Jingping Yun, Rongzhen Luo, Min Zheng

Oncotarget. 2015 Sep 15; 6(27): 23793–23806. Published online 2015 Jun 8. doi: 10.18632/oncotarget.4363

PMCID:: PMC4695152

Abstract Article PDF–3.6M

Select item 444147913.

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition

John L. Goodier, Gavin C. Pereira, Ling E. Cheung, Rebecca J. Rose, Haig H. Kazazian, Jr.

PLoS Genet. 2015 May; 11(5): e1005252. Published online 2015 May 22. doi: 10.1371/journal.pgen.1005252

PMCID:: PMC4441479

Abstract Article PDF–13M

Select item 400717914.

Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: a comparative study with lovastatin

Zuo-quan Xie, Gai Liang, Lu Zhang, Qi Wang, Yi Qu, Yang Gao, Li-bo Lin, Sai Ye, Ji Zhang, Hui Wang, Guo-ping Zhao, Qing-hua Zhang

Acta Pharmacol Sin. 2009 Sep; 30(9): 1262–1275. Published online 2009 Aug 24. doi: 10.1038/aps.2009.126

PMCID:: PMC4007179

Abstract Article PDF–2.0M

Select item 399382515.

3C^pro of Foot-and-Mouth Disease Virus Antagonizes the Interferon Signaling Pathway by Blocking STAT1/STAT2 Nuclear Translocation

Yijun Du, Jingshan Bi, Jiyu Liu, Xing Liu, Xiangju Wu, Ping Jiang, Dongwan Yoo, Yongguang Zhang, Jiaqiang Wu, Renzhong Wan, Xiaomin Zhao, Lihui Guo, Wenbo Sun, Xiaoyan Cong, Lei Chen, Jinbao Wang

J Virol. 2014 May; 88(9): 4908–4920. doi: 10.1128/JVI.03668-13

PMCID:: PMC3993825

Abstract Article PDF–2.0M

Select item 389542816.

Stem cell-like ALDH^bright cellular states in EGFR-mutant non-small cell lung cancer: A novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin

Bruna Corominas-Faja, Cristina Oliveras-Ferraros, Elisabet Cuyàs, Antonio Segura-Carretero, Jorge Joven, Begoña Martin-Castillo, Enrique Barrajón-Catalán, Vicente Micol, Joaquim Bosch-Barrera, Javier A Menendez

Cell Cycle. 2013 Nov 1; 12(21): 3390–3404. Published online 2013 Sep 17. doi: 10.4161/cc.26417

PMCID:: PMC3895428

Abstract Article PDF–1.4M

Select item 382934817.

Serotype-specific Differences in Dengue Virus Non-structural Protein 5 Nuclear Localization

Holger Hannemann, Po-Yu Sung, Han-Chen Chiu, Amjad Yousuf, Jim Bird, Siew Pheng Lim, Andrew D. Davidson

J Biol Chem. 2013 Aug 2; 288(31): 22621–22635. Published online 2013 Jun 13. doi: 10.1074/jbc.M113.481382

PMCID:: PMC3829348

Abstract Article PDF–2.6M

Select item 378330818.

Identification of Gene Expression Signature in Estrogen Receptor Positive Breast Carcinoma

Arvind D. Thakkar, Hemanth Raj, Debarshi Chakrabarti, Ravishankar, N. Saravanan, Bhaskaran Muthuvelan, Arun Balakrishnan, Muralidhara Padigaru

Biomark Cancer. 2010; 2: 1–15. Published online 2010 Feb 11. doi: 10.4137/BIC.S3793

PMCID:: PMC3783308

Abstract Article PDF–6.2M

Select item 363766319.

Polyplex Exposure Inhibits Cell Cycle, Increases Inflammatory Response, and Can Cause Protein Expression Without Cell Division

Rebecca L. Matz, Blake Erickson, Sriram Vaidyanathan, Jolanta F. Kukowska-Latallo, James R. Baker, Jr., Bradford G. Orr, Mark M. Banaszak Holl

Mol Pharm. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: Mol Pharm. 2013 Apr 1; 10(4): 1306–1317. Published online 2013 Mar 21. doi: 10.1021/mp300470d

PMCID:: PMC3637663

Abstract Article PDF–2.3M

Select item 350269420.

Transcriptomic Analysis of Postmortem Brain identifies Dysregulated Splicing Events in Novel Candidate Genes for Schizophrenia

Ori S. Cohen, Sarah Y. Mccoy, Frank A. Middleton, Sean Bialosuknia, Yanli Zhang-James, Lu Liu, Ming T. Tsuang, Stephen V. Faraone, Stephen J. Glatt

Schizophr Res. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Schizophr Res. 2012 Dec; 142(1-3): 188–199. Published online 2012 Oct 9. doi: 10.1016/j.schres.2012.09.015

PMCID:: PMC3502694

Abstract Article PDF–678K

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