PMC Links for Nucleotide (Select 1519312907) - PMC

Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 48821902.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Abstract Article PDF–1.9M

Select item 43766093.

Phosphodiesterase 9A Controls Nitric-oxide Independent cGMP and Hypertrophic Heart Disease

Dong I. Lee, Guangshuo Zhu, Takashi Sasaki, Gun-Sik Cho, Nazha Hamdani, Ronald Holewinski, Su-Hyun Jo, Thomas Danner, Manling Zhang, Peter P. Rainer, Djahida Bedja, Jonathan A. Kirk, Mark J. Ranek, Wolfgang R. Dostmann, Chulan Kwon, Kenneth B. Margulies, Jennifer E. Van Eyk, Walter J. Paulus, Eiki Takimoto, David A. Kass

Nature. Author manuscript; available in PMC 2015 Sep 26.

Published in final edited form as: Nature. 2015 Mar 26; 519(7544): 472–476. Published online 2015 Mar 18. doi: 10.1038/nature14332

PMCID:: PMC4376609

Abstract Article PDF–2.6M

Select item 33404994.

Genome-wide association study of lung function decline in adults with and without asthma

Medea Imboden, Emmanuelle Bouzigon, Ivan Curjuric, Adaikalavan Ramasamy, Ashish Kumar, Dana B Hancock, Jemma B Wilk, Judith M Vonk, Gian A Thun, Valerie Siroux, Rachel Nadif, Florent Monier, Juan R Gonzalez, Matthias Wjst, Joachim Heinrich, Laura R Loehr, Nora Franceschini, Kari E North, Janine Altmüller, Gerard H. Koppelman, Stefano Guerra, Florian Kronenberg, Mark Lathrop, Miriam F Moffatt, George T O’Connor, David P Strachan, Dirkje S Postma, Stephanie J London, Christian Schindler, Manolis Kogevinas, Francine Kauffmann, Debbie L Jarvis, Florence Demenais, Nicole M Probst-Hensch

J Allergy Clin Immunol. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: J Allergy Clin Immunol. 2012 May; 129(5): 1218–1228. Published online 2012 Mar 16. doi: 10.1016/j.jaci.2012.01.074

PMCID:: PMC3340499

Abstract Article PDF–1.1M

Select item 49804155.

Preclinical profile of ITI-214, an inhibitor of phosphodiesterase 1, for enhancement of memory performance in rats

Gretchen L. Snyder, Jos Prickaerts, Marie-Louise Wadenberg, Lei Zhang, Hailin Zheng, Wei Yao, Sven Akkerman, Hongwen Zhu, Joseph P. Hendrick, Kimberly E. Vanover, Robert Davis, Peng Li, Sharon Mates, Lawrence P. Wennogle

Psychopharmacology (Berl) 2016; 233: 3113–3124. Published online 2016 Jun 24. doi: 10.1007/s00213-016-4346-2

PMCID:: PMC4980415

Abstract Article PDF–550K

Select item 42771216.

Pharmacological approaches to improving cognitive function in Down syndrome: current status and considerations

Katheleen J Gardiner

Drug Des Devel Ther. 2015; 9: 103–125. Published online 2014 Dec 17. doi: 10.2147/DDDT.S51476

PMCID:: PMC4277121

Abstract Article PDF–525K

Select item 28184577.

A Critical Period in Cortical Interneuron Neurogenesis in Down Syndrome Revealed by Human Neural Progenitor Cells

Anita Bhattacharyya, Erin McMillan, Serene I. Chen, Kyle Wallace, Clive N. Svendsen

Dev Neurosci. 2009 Nov; 31(6): 497–510. Published online 2009 Sep 9. doi: 10.1159/000236899

PMCID:: PMC2818457

Abstract Article PDF–480K

Select item 27771058.

Expression and Activity of Phosphodiesterase Isoforms during Epithelial Mesenchymal Transition: The Role of Phosphodiesterase 4

Ewa Kolosionek, Rajkumar Savai, Hossein Ardeschir Ghofrani, Norbert Weissmann, Andreas Guenther, Friedrich Grimminger, Werner Seeger, Gamal Andre Banat, Ralph Theo Schermuly, Soni Savai Pullamsetti

Mol Biol Cell. 2009 Nov 15; 20(22): 4751–4765. doi: 10.1091/mbc.E09-01-0019

Correction in:: Mol Biol Cell. 2022 Aug 1; 33(9): cor2.

PMCID:: PMC2777105

Abstract Article PDF–3.5M

Select item 19647669.

Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy

Anna Conti, Floriana Fabbrini, Paola D'Agostino, Rosa Negri, Dario Greco, Rita Genesio, Maria D'Armiento, Carlo Olla, Dario Paladini, Mariastella Zannini, Lucio Nitsch

BMC Genomics. 2007; 8: 268. Published online 2007 Aug 7. doi: 10.1186/1471-2164-8-268

PMCID:: PMC1964766

Abstract Article PDF–1.0M

Select item 135101910.

Isomer-specific regulation of metabolism and PPARγ signaling by CLA in human preadipocytes

J. Mark Brown, Maria Sandberg Boysen, Søren Skov Jensen, Ron F. Morrison, Jayne Storkson, Renee Lea-Currie, Michael Pariza, Susanne Mandrup, Michael K. McIntosh

J Lipid Res. Author manuscript; available in PMC 2006 Jan 25.

Published in final edited form as: J Lipid Res. 2003 Jul; 44(7): 1287–1300. Published online 2003 May 1. doi: 10.1194/jlr.M300001-JLR200

PMCID:: PMC1351019

Abstract Article PDF–967K

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