PMC Links for Nucleotide (Select 241666413) - PMC

Select item 63079461.

TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy

Deepika Sharma, Ankit Malik, Clifford Guy, Peter Vogel, Thirumala-Devi Kanneganti

J Clin Invest. 2019 Jan 2; 129(1): 150–162. Published online 2018 Nov 19. doi: 10.1172/JCI121372

PMCID:: PMC6307946

Select item 62429542.

Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis

Pedro H. V. Saavedra, Linyan Huang, Farzaneh Ghazavi, Stephanie Kourula, Tom Vanden Berghe, Nozomi Takahashi, Peter Vandenabeele, Mohamed Lamkanfi

Nat Commun. 2018; 9: 4846. Published online 2018 Nov 19. doi: 10.1038/s41467-018-07386-5

PMCID:: PMC6242954

Abstract Article PDF–1.5M

Select item 59355773.

IRF8 regulates transcription of Naips for NLRC4 inflammasome activation

Rajendra Karki, Ein Lee, David Place, Parimal Samir, Jayadev Mavuluri, Bhesh Raj Sharma, Arjun Balakrishnan, R. K. Subbarao Malireddi, Rechel Geiger, Qifan Zhu, Geoffrey Neale, Thirumala-Devi Kanneganti

Cell. Author manuscript; available in PMC 2019 May 3.

Published in final edited form as: Cell. 2018 May 3; 173(4): 920–933.e13. Published online 2018 Mar 22. doi: 10.1016/j.cell.2018.02.055

PMCID:: PMC5935577

Abstract Article PDF–2.0M

Select item 58474564.

Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis

Deepika Sharma, Ankit Malik, Clifford S. Guy, Rajendra Karki, Peter Vogel, Thirumala-Devi Kanneganti

Gastroenterology. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: Gastroenterology. 2018 Mar; 154(4): 948–964.e8. Published online 2017 Dec 2. doi: 10.1053/j.gastro.2017.11.276

PMCID:: PMC5847456

Abstract Article PDF–1.2M

Select item 53893725.

IL-1β and Caspase-1 Drive Autoinflammatory Disease Independently of IL-1α or Caspase-8 in a Mouse Model of Familial Mediterranean Fever

Deepika Sharma, Bhesh Raj Sharma, Peter Vogel, Thirumala-Devi Kanneganti

Am J Pathol. 2017 Feb; 187(2): 236–244. doi: 10.1016/j.ajpath.2016.10.015

PMCID:: PMC5389372

Abstract Article PDF–1.7M

Select item 35114136.

Genetic Loss of Murine Pyrin, the Familial Mediterranean Fever Protein, Increases Interleukin-1β Levels

Pamela R. Hesker, MyTrang Nguyen, Martina Kovarova, Jenny P.-Y. Ting, Beverly H. Koller

PLoS One. 2012; 7(11): e51105. Published online 2012 Nov 30. doi: 10.1371/journal.pone.0051105

PMCID:: PMC3511413

Abstract Article PDF–652K

Select item 31296087.

Gain-of-function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1β Activation and Severe Autoinflammation in Mice

Jae Jin Chae, Young-Hun Cho, Geun-Shik Lee, Jun Cheng, P. Paul Liu, Lionel Feigenbaum, Stephen I. Katz, Daniel L. Kastner

Immunity. Author manuscript; available in PMC 2012 May 27.

Published in final edited form as: Immunity. 2011 May 27; 34(5): 755–768. Published online 2011 May 19. doi: 10.1016/j.immuni.2011.02.020

PMCID:: PMC3129608

Abstract Article PDF–3.0M

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