PMC Articles for PubChem Compound (Select 10200390) - PMC

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Items: 19

Select item 91793261.

Pharmacological Inhibition of Spleen Tyrosine Kinase Suppressed Neuroinflammation and Cognitive Dysfunction in LPS-Induced Neurodegeneration Model

Min Woo Kim, Kyonghwan Choe, Jun Sung Park, Hyeon Jin Lee, Min Hwa Kang, Riaz Ahmad, Myeong Ok Kim

Cells. 2022 Jun; 11(11): 1777. Published online 2022 May 28. doi: 10.3390/cells11111777

PMCID:: PMC9179326

Abstract Article PDF–4.4M

Select item 86123042.

BAY61-3606 attenuates neuroinflammation and neurofunctional damage by inhibiting microglial Mincle/Syk signaling response after traumatic brain injury

Xuejun He, Yimin Huang, Yanchao Liu, Xincheng Zhang, Pengjie Yue, Xiaopeng Ma, Zhuangzhuang Miao, Xiaobing Long, Yiping Yang, Xueyan Wan, Jin Lei, Kai Shu, Ting Lei, Chao Gan, Huaqiu Zhang

Int J Mol Med. 2022 Jan; 49(1): 5. Published online 2021 Nov 9. doi: 10.3892/ijmm.2021.5060

PMCID:: PMC8612304

Abstract Article PDF–8.1M

Select item 82550623.

Fcγ receptor activation mediates vascular inflammation and abdominal aortic aneurysm development

Laura Lopez‐Sanz, Susana Bernal, Luna Jimenez‐Castilla, Ignacio Prieto, Sara La Manna, Sergio Gomez‐Lopez, Luis Miguel Blanco‐Colio, Jesus Egido, Jose Luis Martin‐Ventura, Carmen Gomez‐Guerrero

Clin Transl Med. 2021 Jul; 11(7): e463. Published online 2021 Jul 4. doi: 10.1002/ctm2.463

PMCID:: PMC8255062

Abstract Article PDF–11M

Select item 75301714.

High-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity Against Mycobacterium tuberculosis

Tirosh Shapira, Leah Rankine-Wilson, Joseph D. Chao, Virginia Pichler, Celine Rens, Tom Pfeifer, Yossef Av-Gay

Front Microbiol. 2020; 11: 553962. Published online 2020 Sep 18. doi: 10.3389/fmicb.2020.553962

PMCID:: PMC7530171

Abstract Article PDF–1.7M

Select item 71243195.

Comparison of the anti-allergic activity of Syk inhibitors with optimized Syk siRNAs in FcεRI-activated RBL-2H3 basophilic cells

Michael P. Sanderson, Stephen J. Gelling, Jörg F. Rippmann, Andreas Schnapp

Cell Immunol. 2010; 262(1): 28–34. Published online 2009 Dec 16. doi: 10.1016/j.cellimm.2009.12.004

PMCID:: PMC7124319

Abstract Article PDF–546K

Select item 62149306.

PMA inhibits endothelial cell migration through activating the PKC-δ/Syk/NF-κB-mediated up-regulation of Thy-1

Heng-Ching Wen, Yen Nien Huo, Chih-Ming Chou, Wen-Sen Lee

Sci Rep. 2018; 8: 16247. Published online 2018 Nov 2. doi: 10.1038/s41598-018-34548-8

PMCID:: PMC6214930

Abstract Article PDF–3.1M

Select item 52445497.

A spleen tyrosine kinase inhibitor attenuates the proliferation and migration of vascular smooth muscle cells

Hyang-Hee Seo, Sang Woo Kim, Chang Youn Lee, Kyu Hee Lim, Jiyun Lee, Eunhyun Choi, Soyeon Lim, Seahyoung Lee, Ki-Chul Hwang

Biol Res. 2017; 50: 1. Published online 2017 Jan 18. doi: 10.1186/s40659-016-0106-3

PMCID:: PMC5244549

Abstract Article PDF–1.4M

Select item 48695618.

Effect of Narrow Spectrum Versus Selective Kinase Inhibitors on the Intestinal Proinflammatory Immune Response in Ulcerative Colitis

Paolo Biancheri, Martyn R. Foster, Matthew C. T. Fyfe, Thomas T. MacDonald, Sameer Sirohi, Yemisi Solanke, Eleanor Wood, Adele Rowley, Steve Webber, Claire A. Walshe

Inflamm Bowel Dis. 2016 Jun; 22(6): 1306–1315. Published online 2016 Apr 22. doi: 10.1097/MIB.0000000000000759

PMCID:: PMC4869561

Abstract Article PDF–627K

Select item 47730989.

Inhibition of IKKα by BAY61-3606 Reveals IKKα-Dependent Histone H3 Phosphorylation in Human Cytomegalovirus Infected Cells

Catherine M. K. Ho, I’ah Z. Donovan-Banfield, Li Tan, Tinghu Zhang, Nathanael S. Gray, Blair L. Strang

PLoS One. 2016; 11(3): e0150339. Published online 2016 Mar 1. doi: 10.1371/journal.pone.0150339

PMCID:: PMC4773098

Abstract Article PDF–7.3M

Select item 469783710.

Bay 61-3606 Sensitizes TRAIL-Induced Apoptosis by Downregulating Mcl-1 in Breast Cancer Cells

So-Young Kim, Sang Eun Park, Sang-Mi Shim, Sojung Park, Kyung Kon Kim, Seong-Yun Jeong, Eun Kyung Choi, Jung Jin Hwang, Dong-Hoon Jin, Christopher Doosoon Chung, Inki Kim

PLoS One. 2015; 10(12): e0146073. Published online 2015 Dec 31. doi: 10.1371/journal.pone.0146073

PMCID:: PMC4697837

Abstract Article PDF–3.8M

Select item 369024911.

Exacerbation of Glycoprotein VI-Dependent Platelet Responses in a Rhesus Monkey Model of Type 1 Diabetes

J. F. Arthur, Y. Shen, Y. Chen, J. Qiao, R. Ni, Y. Lu, R. K. Andrews, E. E. Gardiner, J. Cheng

J Diabetes Res. 2013; 2013: 370212. Published online 2013 Jun 6. doi: 10.1155/2013/370212

PMCID:: PMC3690249

Abstract Article PDF–999K

Select item 357053012.

Adiponectin Regulates Vascular Endothelial Growth Factor-C Expression in Macrophages via Syk-ERK Pathway

Di Hu, Atsunori Fukuhara, Yugo Miyata, Chieko Yokoyama, Michio Otsuki, Shinji Kihara, Iichiro Shimomura

PLoS One. 2013; 8(2): e56071. Published online 2013 Feb 12. doi: 10.1371/journal.pone.0056071

PMCID:: PMC3570530

Abstract Article PDF–491K

Select item 346449513.

Jedi-1 and MEGF10 Signal Engulfment of Apoptotic Neurons through the Tyrosine Kinase Syk

Jami L. Scheib, Chelsea S. Sullivan, Bruce D. Carter

J Neurosci. 2012 Sep 19; 32(38): 13022–13031. doi: 10.1523/JNEUROSCI.6350-11.2012

PMCID:: PMC3464495

Abstract Article PDF–1.9M

Select item 339981714.

BAY61-3606 Affects the Viability of Colon Cancer Cells in a Genotype-Directed Manner

Ken S. Lau, Tinghu Zhang, Krystle R. Kendall, Douglas Lauffenburger, Nathanael S. Gray, Kevin M. Haigis

PLoS One. 2012; 7(7): e41343. Published online 2012 Jul 18. doi: 10.1371/journal.pone.0041343

PMCID:: PMC3399817

Abstract Article PDF–1.5M

Select item 337135115.

Osteosarcoma Phenotype Is Inhibited by 3,4-Methylenedioxy-β-nitrostyrene

Patrick J. Messerschmitt, Ashley N. Rettew, Nicholas O. Schroeder, Robert E. Brookover, Avanti P. Jakatdar, Patrick J. Getty, Edward M. Greenfield

Sarcoma. 2012; 2012: 479712. Published online 2012 May 31. doi: 10.1155/2012/479712

PMCID:: PMC3371351

Abstract Article PDF–3.7M

Select item 317972316.

Treatment of allergic asthma: Modulation of Th2 cells and their responses

Berislav Bosnjak, Barbara Stelzmueller, Klaus J Erb, Michelle M Epstein

Respir Res. 2011; 12(1): 114. Published online 2011 Aug 25. doi: 10.1186/1465-9921-12-114

PMCID:: PMC3179723

Abstract Article PDF–778K

Select item 312358617.

Central nervous system mast cells in peripheral inflammatory nociception

Dimitris N Xanthos, Simon Gaderer, Ruth Drdla, Erin Nuro, Anastasia Abramova, Wilfried Ellmeier, Jürgen Sandkühler

Mol Pain. 2011; 7: 42. Published online 2011 Jun 3. doi: 10.1186/1744-8069-7-42

PMCID:: PMC3123586

Abstract Article PDF–1.8M

Select item 292001718.

A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk

E Katz, S Dubois-Marshall, A H Sims, D Faratian, J Li, E S Smith, J A Quinn, M Edward, R R Meehan, E E Evans, S P Langdon, D J Harrison

Br J Cancer. 2010 Jul 27; 103(3): 401–410. Published online 2010 Jul 13. doi: 10.1038/sj.bjc.6605763

PMCID:: PMC2920017

Abstract Article PDF–840K

Select item 272177419.

Kinase inhibitors for the treatment of inflammatory and autoimmune disorders

Shripad S. Bhagwat

Purinergic Signal. 2009 Mar; 5(1): 107–115. Published online 2008 Jun 21. doi: 10.1007/s11302-008-9117-z

PMCID:: PMC2721774

Abstract Article PDF–347K

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