PMC Articles for PubChem Compound (Select 46843772) - PMC

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Items: 10

Select item 69236061.

Pharmacological inhibition of the MEK5/ERK5 and PI3K/Akt signaling pathways synergistically reduces viability in triple-negative breast cancer

Thomas D Wright, Christopher Raybuck, Akshita Bhatt, Darlene Monlish, Suravi Chakrabarty, Katy Wendekier, Nathan Gartland, Mohit Gupta, Matthew E Burow, Patrick T Flaherty, Jane E Cavanaugh

J Cell Biochem. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: J Cell Biochem. 2020 Feb; 121(2): 1156–1168. Published online 2019 Aug 28. doi: 10.1002/jcb.29350

PMCID:: PMC6923606

Abstract Article PDF–1.4M

Select item 64485982.

ROS amplification drives mouse spermatogonial stem cell self-renewal

Hiroko Morimoto, Mito Kanastu-Shinohara, Narumi Ogonuki, Satoshi Kamimura, Atsuo Ogura, Chihiro Yabe-Nishimura, Yoshifumi Mori, Takeshi Morimoto, Satoshi Watanabe, Kinya Otsu, Takuya Yamamoto, Takashi Shinohara

Life Sci Alliance. 2019 Apr; 2(2): e201900374. Published online 2019 Apr 2. doi: 10.26508/lsa.201900374

PMCID:: PMC6448598

Abstract Article PDF–2.5M

Select item 61788863.

Targeting the Extracellular Signal-Regulated Kinase 5 Pathway to Suppress Human Chronic Myeloid Leukemia Stem Cells

Ignazia Tusa, Giulia Cheloni, Martina Poteti, Antonella Gozzini, Ngoc Ho DeSouza, Yi Shan, Xianming Deng, Nathanael S. Gray, Shaoguang Li, Elisabetta Rovida, Persio Dello Sbarba

Stem Cell Reports. 2018 Oct 9; 11(4): 929–943. Published online 2018 Sep 20. doi: 10.1016/j.stemcr.2018.08.016

PMCID:: PMC6178886

Abstract Article PDF–2.4M

Select item 50851594.

MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism

Diane M. Pereira, André E. S. Simões, Sofia E. Gomes, Rui E. Castro, Tânia Carvalho, Cecília M. P. Rodrigues, Pedro M. Borralho

Oncotarget. 2016 Jun 7; 7(23): 34322–34340. Published online 2016 Apr 29. doi: 10.18632/oncotarget.9107

PMCID:: PMC5085159

Abstract Article PDF–8.7M

Select item 49638605.

EGCG Suppresses ERK5 Activation to Reverse Tobacco Smoke-Triggered Gastric Epithelial-Mesenchymal Transition in BALB/c Mice

Ling Lu, Jia Chen, Hua Tang, Ling Bai, Chun Lu, Kehuan Wang, Manli Li, Yinmei Yan, Ling Tang, Rui Wu, Yang Ye, Longtao Jin, Zhaofeng Liang

Nutrients. 2016 Jul; 8(7): 380. Published online 2016 Jul 20. doi: 10.3390/nu8070380

PMCID:: PMC4963860

Abstract Article PDF–3.6M

Select item 47417656.

Inhibition of BMK1 pathway suppresses cancer stem cells through BNIP3 and BNIP3L

Chengli Song, Qiang Xu, Kui Jiang, Guangyu Zhou, Xuebin Yu, Lina Wang, Yuting Zhu, Liping Fang, Zhe Yu, Jiing-Dwan Lee, Shi-Cang Yu, Qingkai Yang

Oncotarget. 2015 Oct 20; 6(32): 33279–33289. Published online 2015 Sep 29. doi: 10.18632/oncotarget.5337

PMCID:: PMC4741765

Abstract Article PDF–6.4M

Select item 44017657.

ERK5 Activation Is Essential for Osteoclast Differentiation

Shigeru Amano, Yu-Tzu Chang, Yasuhisa Fukui

PLoS One. 2015; 10(4): e0125054. Published online 2015 Apr 17. doi: 10.1371/journal.pone.0125054

PMCID:: PMC4401765

Abstract Article PDF–1.3M

Select item 43639888.

ERK5 Pathway Regulates Transcription Factors Important for Monocytic Differentiation of Human Myeloid Leukemia Cells

Xuening Wang, Stella Pesakhov, Jonathan S Harrison, Michael Danilenko, George P Studzinski

J Cell Physiol. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: J Cell Physiol. 2014 Jul; 229(7): 856–867. doi: 10.1002/jcp.24513

PMCID:: PMC4363988

Abstract Article PDF–1.7M

Select item 31079139.

Targeting the BMK1 MAP Kinase Pathway in Cancer Therapy

Qingkai Yang, Jiing-Dwan Lee

Clin Cancer Res. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Clin Cancer Res. 2011 Jun 1; 17(11): 3527–3532. Published online 2011 Mar 8. doi: 10.1158/1078-0432.CCR-10-2504

PMCID:: PMC3107913

Abstract Article PDF–101K

Select item 293972910.

Pharmacological Inhibition of BMK1 Suppresses Tumor Growth Through PML

Qingkai Yang, Xianming Deng, Bingwen Lu, Michael Cameron, Colleen Fearns, Matthew P. Patricelli, John R. Yates, III, Nathanael S. Gray, Jiing-Dwan Lee

Cancer Cell. Author manuscript; available in PMC 2011 Sep 14.

Published in final edited form as: Cancer Cell. 2010 Sep 14; 18(3): 258–267. doi: 10.1016/j.ccr.2010.08.008