PMC Articles for PubChem Compound (Select 57495353) - PMC

Select item 101632801.

A randomized, placebo-controlled phase 3 trial of the PI3Kδ inhibitor leniolisib for activated PI3Kδ syndrome

V. Koneti Rao, Sharon Webster, Anna Šedivá, Alessandro Plebani, Catharina Schuetz, Anna Shcherbina, Niall Conlon, Tanya Coulter, Virgil A. Dalm, Antonino Trizzino, Yulia Zharankova, Elaine Kulm, Julia Körholz, Vassilios Lougaris, Yulia Rodina, Kath Radford, Jason Bradt, Klaus Kucher, Anurag Relan, Steven M. Holland, Michael J. Lenardo, Gulbu Uzel

Blood. 2023 Mar 2; 141(9): 971–983. Published online 2022 Nov 21. doi: 10.1182/blood.2022018546

PMCID:: PMC10163280

Abstract Article

Select item 71606572.

The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology

Simon D. Harding, Elena Faccenda, Christopher Southan, Adam J. Pawson, Pasquale Maffia, Stephen P. H. Alexander, Anthony P. Davenport, Doriano Fabbro, Francesca Levi‐Schaffer, Michael Spedding, Jamie A. Davies

Immunology. 2020 May; 160(1): 10–23. Published online 2020 Mar 2. doi: 10.1111/imm.13175

PMCID:: PMC7160657

Abstract Article PDF–4.1M

Select item 60829333.

Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8⁺ T Cell Survival, Differentiation, and Function

Jennifer L. Cannons, Silvia Preite, Senta M. Kapnick, Gulbu Uzel, Pamela L. Schwartzberg

Front Immunol. 2018; 9: 1758. Published online 2018 Aug 2. doi: 10.3389/fimmu.2018.01758

PMCID:: PMC6082933

Abstract Article PDF–1.3M

Select item 57015264.

Effective “activated PI3Kδ syndrome”–targeted therapy with the PI3Kδ inhibitor leniolisib

V. Koneti Rao, Sharon Webster, Virgil A. S. H. Dalm, Anna Šedivá, P. Martin van Hagen, Steven Holland, Sergio D. Rosenzweig, Andreas D. Christ, Birgitte Sloth, Maciej Cabanski, Aniket D. Joshi, Stefan de Buck, Julie Doucet, Danilo Guerini, Christoph Kalis, Ilona Pylvaenaeinen, Nicolas Soldermann, Anuj Kashyap, Gulbu Uzel, Michael J. Lenardo, Dhavalkumar D. Patel, Carrie L. Lucas, Christoph Burkhart

Blood. 2017 Nov 23; 130(21): 2307–2316. Prepublished online 2017 Sep 29. doi: 10.1182/blood-2017-08-801191

PMCID:: PMC5701526

Abstract Article

Select item 56013755.

Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors

Klemens Hoegenauer, Nicolas Soldermann, Frédéric Zécri, Ross S. Strang, Nadege Graveleau, Romain M. Wolf, Nigel G. Cooke, Alexander B. Smith, Gregory J. Hollingworth, Joachim Blanz, Sascha Gutmann, Gabriele Rummel, Amanda Littlewood-Evans, Christoph Burkhart

ACS Med Chem Lett. 2017 Sep 14; 8(9): 975–980. Published online 2017 Aug 25. doi: 10.1021/acsmedchemlett.7b00293

PMCID:: PMC5601375

Abstract Article PDF–1.5M

Select item 42099626.

Dominant-Activating, Germline Mutations in Phosphoinositide 3-Kinase p110δ Cause T Cell Senescence and Human Immunodeficiency

Carrie L. Lucas, Hye Sun Kuehn, Fang Zhao, Julie E. Niemela, Elissa K. Deenick, Umaimainthan Palendira, Danielle T. Avery, Leen Moens, Jennifer L. Cannons, Matthew Biancalana, Jennifer Stoddard, Weiming Ouyang, David L. Frucht, V. Koneti Rao, T. Prescott Atkinson, Anahita Agharahimi, Ashleigh A. Hussey, Les R. Folio, Kenneth N. Olivier, Thomas A. Fleisher, Stefania Pittaluga, Steven M. Holland, Jeffrey I. Cohen, Joao B. Oliviera, Stuart G. Tangye, Pamela L. Schwartzberg, Michael J. Lenardo, Gulbu Uzel

Nat Immunol. Author manuscript; available in PMC 2014 Oct 27.

Published in final edited form as: Nat Immunol. 2014 Jan; 15(1): 88–97. Published online 2013 Oct 28. doi: 10.1038/ni.2771

PMCID:: PMC4209962

Abstract Article PDF–3.4M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from PubChem Compound

Items: 6

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity