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Items: 1 to 20 of 82

1.
Teaching an Old GABA Receptor New Tricks
James R. Trudell, Edward Bertaccini, Bruce M. MacIver
Anesth Analg. Author manuscript; available in PMC 2015 May 26.
Published in final edited form as: Anesth Analg. 2012 Aug; 115(2): 270–273. Published online 2012 Feb 17. doi: 10.1213/ANE.0b013e31824a0b3c
PMCID:
PMC4444214
AbstractArticlePDF–477K
2.
Aminobutyric Acid Type A Receptor β3 Subunit Forebrain-Specific Knockout Mice Are Resistant to the Amnestic Effect of Isoflurane
Vinuta Rau, Irene Oh, Christina Bodarky, Michael S. Fanselow, Gregg E. Homanics, James M. Sonner, Edmond I Eger, II
Anesth Analg. Author manuscript; available in PMC 2014 Apr 29.
Published in final edited form as: Anesth Analg. 2011 Sep; 113(3): 500–504. Published online 2011 Aug 3. doi: 10.1213/ANE.0b013e3182273aff
PMCID:
PMC4003562
AbstractArticlePDF–493K
3.
Monod-Wyman-Changeux Allosteric Mechanisms of Action and the Pharmacology of Etomidate
Stuart A. Forman
Curr Opin Anaesthesiol. Author manuscript; available in PMC 2013 Jun 5.
Published in final edited form as: Curr Opin Anaesthesiol. 2012 Aug; 25(4): 411–418. doi: 10.1097/ACO.0b013e328354feea
PMCID:
PMC3673006
AbstractArticlePDF–1.4M
4.
The Pyrrole Etomidate Analog Carboetomidate Potently Inhibits Human 5-HT3A Receptor Function: Comparisons with Etomidate and Potential Implications for Emetogenesis
Rooma Desai, Keith W. Miller, Douglas E. Raines
Anesth Analg. Author manuscript; available in PMC 2014 Mar 1.
Published in final edited form as: Anesth Analg. 2013 Mar; 116(3): 573–579. Published online 2013 Feb 11. doi: 10.1213/ANE.0b013e31827d204d
PMCID:
PMC3582768
AbstractArticlePDF–1008K
5.
Closed-loop Continuous Infusions of Etomidate and Etomidate Analogs in Rats: A Comparative Study of Dosing and the Impact on Adrenocortical Function
Joseph F. Cotten, Ri Le Ge, Natalie Banacos, Ervin Pejo, S. Shaukat Husain, James H. Williams, Douglas E. Raines
Anesthesiology. Author manuscript; available in PMC 2013 Jan 2.
Published in final edited form as: Anesthesiology. 2011 Oct; 115(4): 764–773. doi: 10.1097/ALN.0b013e31821950de
PMCID:
PMC3534755
AbstractArticlePDF–1.9M
6.
Medical management of Cushing’s disease: what is the future?
Maria Fleseriu, Stephan Petersenn
Pituitary. 2012; 15(3): 330–341. Published online 2012 Jun 7. doi: 10.1007/s11102-012-0397-5
PMCID:
PMC3443360
AbstractArticlePDF–601K
7.
Carboetomidate Inhibits Alpha4/Beta2 Neuronal Nicotinic Acetylcholine Receptors at Concentrations Affecting Animals
David W. Pierce, Ervin Pejo, Douglas E. Raines, Stuart A. Forman
Anesth Analg. Author manuscript; available in PMC 2013 Jul 1.
Published in final edited form as: Anesth Analg. 2012 Jul; 115(1): 70–72. Published online 2012 Apr 27. doi: 10.1213/ANE.0b013e318254273e
PMCID:
PMC3381859
AbstractArticlePDF–622K
8.
The Two Etomidate Sites in α1β2γ2 GABAA Receptors Contribute Equally and Non-cooperatively to Modulation of Channel Gating
Grigori Guitchounts, Deirdre S. Stewart, Stuart A. Forman
Anesthesiology. Author manuscript; available in PMC 2013 Jun 1.
Published in final edited form as: Anesthesiology. 2012 Jun; 116(6): 1235–1244. doi: 10.1097/ALN.0b013e3182567df3
PMCID:
PMC3366439
AbstractArticlePDF–3.3M
9.
Mutations in the GABAA receptor that mimic the allosteric ligand, etomidate
Stuart A. Forman, Deirdre Stewart
Methods Mol Biol. Author manuscript; available in PMC 2013 Jan 1.
Published in final edited form as: Methods Mol Biol. 2012; 796: 317–333. doi: 10.1007/978-1-61779-334-9_17
PMCID:
PMC3360466
AbstractArticlePDF–386K
10.
Prospective study comparing skin impedance with EEG parameters during the induction of anaesthesia with fentanyl and etomidate
M Winterhalter, S Münte, M Gerhard, O Danzeisen, T Jüttner, E Monaca, L Hoy, N Rahe-Meyer, P Kienbaum
Eur J Med Res. 2010; 15(2): 47–53. Published online 2010 Feb 26. doi: 10.1186/2047-783X-15-2-47
PMCID:
PMC3352044
AbstractArticlePDF–1.5M
11.
Electroencephalographic Recovery, Hypnotic Emergence, and the Effects of Metabolite Following Continuous Infusions of a Rapidly Metabolized Etomidate Analog in Rats
Ervin Pejo, Rile Ge, Natalie Banacos, Joseph F. Cotten, S. Shaukat Husain, Douglas E. Raines
Anesthesiology. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Anesthesiology. 2012 May; 116(5): 1057–1065. doi: 10.1097/ALN.0b013e3182515403
PMCID:
PMC3351719
AbstractArticlePDF–2.4M
12.
Etomidate and mortality in cirrhotic patients with septic shock
Antoine J Cherfan, Hani M Tamim, Abdulrahman AlJumah, Asgar H Rishu, Abdulmajeed Al-Abdulkareem, Bandar A Al Knawy, Ali Hajeer, Waleed Tamimi, Riette Brits, Yaseen M Arabi
BMC Clin Pharmacol. 2011; 11: 22. Published online 2011 Dec 30. doi: 10.1186/1472-6904-11-22
PMCID:
PMC3295685
AbstractArticlePDF–332K
13.
Pharmacological Studies of Methoxycarbonyl Etomidate's Carboxylic Acid Metabolite
Ri Le Ge, Ervin Pejo, Marian Haburcak, S. Shaukat Husain, Stuart A. Forman, Douglas E. Raines
Anesth Analg. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: Anesth Analg. 2012 Aug; 115(2): 305–308. Published online 2011 Nov 3. doi: 10.1213/ANE.0b013e318239c6ca
PMCID:
PMC3291806
AbstractArticlePDF–622K
14.
Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [3H]TDBzl-etomidate, a photoreactive etomidate analog
David C. Chiara, Zuzana Dostalova, Selwyn S. Jayakar, Xiaojuan Zhou, Keith W. Miller, Jonathan B. Cohen
Biochemistry. Author manuscript; available in PMC 2013 Jan 31.
Published in final edited form as: Biochemistry. 2012 Jan 31; 51(4): 836–847. Published online 2012 Jan 23. doi: 10.1021/bi201772m
PMCID:
PMC3274767
AbstractArticlePDF–1.9M
15.
The TM2 6′ Position of GABAA Receptors Mediates Alcohol Inhibition
W. David Johnson, II, Rebecca J. Howard, James R. Trudell, R. Adron Harris
J Pharmacol Exp Ther. 2012 Feb; 340(2): 445–456. doi: 10.1124/jpet.111.188037
PMCID:
PMC3263960
AbstractArticlePDF–1.8M
16.
An Allosteric Coagonist Model for Propofol Effects on α1β2γ2L γ-Aminobutyric Acid Type A Receptors
Dirk Ruesch, Elena Neumann, Hinnerk Wulf, Stuart A. Forman
Anesthesiology. Author manuscript; available in PMC 2013 Jan 1.
Published in final edited form as: Anesthesiology. 2012 Jan; 116(1): 47–55. doi: 10.1097/ALN.0b013e31823d0c36
PMCID:
PMC3261780
AbstractArticlePDF–1.7M
17.
In Vivo and In Vitro Pharmacological Studies of Methoxycarbonyl-Carboetomidate
Ervin Pejo, Joseph F. Cotten, Elizabeth W. Kelly, Ri Le Ge, Gregory D. Cuny, Joydev K. Laha, Jifeng Liu, Xiang Jie Lin, Douglas E. Raines
Anesth Analg. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: Anesth Analg. 2012 Aug; 115(2): 297–304. Published online 2011 Sep 29. doi: 10.1213/ANE.0b013e3182320559
PMCID:
PMC3252484
AbstractArticlePDF–1.4M
18.
Differential Effects of Etomidate and its Pyrrole Analogue Carboetomidate on the Adrenocortical and Cytokine Responses to Endotoxemia
Ervin Pejo, Yan Feng, Wei Chao, Joseph F Cotten, Ri Le Ge, Douglas E Raines
Crit Care Med. Author manuscript; available in PMC 2013 Jan 1.
Published in final edited form as: Crit Care Med. 2012 Jan; 40(1): 187–192. doi: 10.1097/CCM.0b013e31822d7924
PMCID:
PMC3242859
AbstractArticlePDF–897K
19.
Multiple Transmembrane Binding Sites for p-Trifluoromethyldiazirinyl-etomidate, a Photoreactive Torpedo Nicotinic Acetylcholine Receptor Allosteric Inhibitor
Ayman K. Hamouda, Deirdre S. Stewart, S. Shaukat Husain, Jonathan B. Cohen
J Biol Chem. 2011 Jun 10; 286(23): 20466–20477. Published online 2011 Apr 15. doi: 10.1074/jbc.M111.219071
PMCID:
PMC3121496
AbstractArticlePDF–3.7M
20.
p-Trifluoromethyldiazirinyl-etomidate: a potent photoreactive general anesthetic derivative of etomidate that is selective for ligand-gated cationic ion channels
S. Shaukat Husain, Deirdre Stewart, Rooma Desai, Ayman K. Hamouda, S. Guo-Dong Li, Elizabeth Kelly, Zuzana Dostalova, Xiaojuan Zhou, Joseph F. Cotten, Douglas A. Raines, Richard W. Olsen, Jonathan B. Cohen, Stuart A. Forman, Keith W. Miller
J Med Chem. Author manuscript; available in PMC 2011 Sep 9.
Published in final edited form as: J Med Chem. 2010 Sep 9; 53(17): 6432–6444. doi: 10.1021/jm100498u
PMCID:
PMC3117435
AbstractArticlePDF–1.4M

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