PMC Links for Protein (Select 1077172581) - PMC

Select item 60750331.

The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis

Yingying Zhang, Aaron Burberry, Jin-Yuan Wang, Jackson Sandoe, Sulagna Ghosh, Namrata D. Udeshi, Tanya Svinkina, Daniel A. Mordes, Joanie Mok, Maura Charlton, Quan-Zhen Li, Steven A. Carr, Kevin Eggan

Genes Dev. 2018 Jul 1; 32(13-14): 929–943. doi: 10.1101/gad.313932.118

PMCID:: PMC6075033

Abstract Article PDF–6.0M

Select item 53230462.

Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator

Jennifer Jung, Arnab Nayak, Véronique Schaeffer, Tatjana Starzetz, Achim K Kirsch, Stefan Müller, Ivan Dikic, Michel Mittelbronn, Christian Behrends

eLife. 2017; 6: e23063. Published online 2017 Feb 14. doi: 10.7554/eLife.23063

PMCID:: PMC5323046

Abstract Article PDF–5.8M

Select item 49695713.

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

Christopher P Webster, Emma F Smith, Claudia S Bauer, Annekathrin Moller, Guillaume M Hautbergue, Laura Ferraiuolo, Monika A Myszczynska, Adrian Higginbottom, Matthew J Walsh, Alexander J Whitworth, Brian K Kaspar, Kathrin Meyer, Pamela J Shaw, Andrew J Grierson, Kurt J De Vos

EMBO J. 2016 Aug 1; 35(15): 1656–1676. Published online 2016 Jun 22. doi: 10.15252/embj.201694401

PMCID:: PMC4969571

Abstract Article PDF–3.2M

Select item 26639204.

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

Chang Hwa Jung, Chang Bong Jun, Seung-Hyun Ro, Young-Mi Kim, Neil Michael Otto, Jing Cao, Mondira Kundu, Do-Hyung Kim

Mol Biol Cell. 2009 Apr 1; 20(7): 1992–2003. doi: 10.1091/mbc.E08-12-1249

PMCID:: PMC2663920

Abstract Article PDF–728K

Select item 26639155.

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

Nao Hosokawa, Taichi Hara, Takeshi Kaizuka, Chieko Kishi, Akito Takamura, Yutaka Miura, Shun-ichiro Iemura, Tohru Natsume, Kenji Takehana, Naoyuki Yamada, Jun-Lin Guan, Noriko Oshiro, Noboru Mizushima

Mol Biol Cell. 2009 Apr 1; 20(7): 1981–1991. doi: 10.1091/mbc.E08-12-1248

PMCID:: PMC2663915

Abstract Article PDF–669K

Select item 26124946.

Kinase-Inactivated ULK Proteins Inhibit Autophagy via Their Conserved C-Terminal Domains Using an Atg13-Independent Mechanism

Edmond Y. W. Chan, Andrea Longatti, Nicole C. McKnight, Sharon A. Tooze

Mol Cell Biol. 2009 Jan; 29(1): 157–171. Published online 2008 Oct 20. doi: 10.1128/MCB.01082-08

PMCID:: PMC2612494

Abstract Article PDF–2.7M

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