PMC Links for Protein (Select 148887370) - PMC

Select item 36770931.

Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition

Meera Soundararajan, Annette K. Roos, Pavel Savitsky, Panagis Filippakopoulos, Arminja N. Kettenbach, Jesper V. Olsen, Scott A. Gerber, Jeyanthy Eswaran, Stefan Knapp, Jonathan M. Elkins

Structure. 2013 Jun 4; 21(6): 986–996. doi: 10.1016/j.str.2013.03.012

PMCID:: PMC3677093

Abstract Article PDF–2.5M

Select item 35916332.

Dyrk2-associated EDD-DDB1-VprBP E3 Ligase Inhibits Telomerase by TERT Degradation

Hae-Yun Jung, Xin Wang, Sohee Jun, Jae-Il Park

J Biol Chem. 2013 Mar 8; 288(10): 7252–7262. Published online 2013 Jan 28. doi: 10.1074/jbc.M112.416792

PMCID:: PMC3591633

Abstract Article PDF–2.6M

Select item 32873833.

DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells

Naoe Taira, Rei Mimoto, Morito Kurata, Tomoko Yamaguchi, Masanobu Kitagawa, Yoshio Miki, Kiyotsugu Yoshida

J Clin Invest. 2012 Mar 1; 122(3): 859–872. Published online 2012 Feb 6. doi: 10.1172/JCI60818

PMCID:: PMC3287383

Abstract Article PDF–2.3M

Select item 31184654.

Structure–activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors

Gregory D. Cuny, Maxime Robin, Natalia P. Ulyanova, Debasis Patnaik, Valerie Pique, Gilles Casano, Ji-Feng Liu, Xiangjie Lin, Jun Xian, Marcie A. Glicksman, Ross L. Stein, Jonathan M. G. Higgins

Bioorg Med Chem Lett. Author manuscript; available in PMC 2011 Jun 20.

Published in final edited form as: Bioorg Med Chem Lett. 2010 Jun 15; 20(12): 3491–3494.

PMCID:: PMC3118465

Abstract Article PDF–964K

Select item 28360955.

ATM Augments Nuclear Stabilization of DYRK2 by Inhibiting MDM2 in the Apoptotic Response to DNA Damage

Naoe Taira, Hiroyuki Yamamoto, Tomoko Yamaguchi, Yoshio Miki, Kiyotsugu Yoshida

J Biol Chem. 2010 Feb 12; 285(7): 4909–4919. Published online 2009 Dec 4. doi: 10.1074/jbc.M109.042341

PMCID:: PMC2836095

Abstract Article PDF–2.5M

Select item 27540756.

Protein kinase DYRK2 is an E3-ligase specific molecular assembler

Subbareddy Maddika, Junjie Chen

Nat Cell Biol. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: Nat Cell Biol. 2009 Apr; 11(4): 409–419. Published online 2009 Mar 15. doi: 10.1038/ncb1848

PMCID:: PMC2754075

Abstract Article PDF–4.6M

Select item 27127197.

Patterns of somatic mutation in human cancer genomes

Christopher Greenman, Philip Stephens, Raffaella Smith, Gillian L. Dalgliesh, Christopher Hunter, Graham Bignell, Helen Davies, Jon Teague, Adam Butler, Claire Stevens, Sarah Edkins, Sarah O'Meara, Imre Vastrik, Esther E. Schmidt, Tim Avis, Syd Barthorpe, Gurpreet Bhamra, Gemma Buck, Bhudipa Choudhury, Jody Clements, Jennifer Cole, Ed Dicks, Simon Forbes, Kris Gray, Kelly Halliday, Rachel Harrison, Katy Hills, Jon Hinton, Andy Jenkinson, David Jones, Andy Menzies, Tatiana Mironenko, Janet Perry, Keiran Raine, Dave Richardson, Rebecca Shepherd, Alexandra Small, Calli Tofts, Jennifer Varian, Tony Webb, Sofie West, Sara Widaa, Andy Yates, Daniel P. Cahill, David N. Louis, Peter Goldstraw, Andrew G. Nicholson, Francis Brasseur, Leendert Looijenga, Barbara L. Weber, Yoke-Eng Chiew, Anna deFazio, Mel F. Greaves, Anthony R. Green, Peter Campbell, Ewan Birney, Douglas F. Easton, Georgia Chenevix-Trench, Min-Han Tan, Sok Kean Khoo, Bin Tean Teh, Siu Tsan Yuen, Suet Yi Leung, Richard Wooster, P. Andrew Futreal, Michael R. Stratton

Nature. Author manuscript; available in PMC 2009 Jul 20.

Published in final edited form as: Nature. 2007 Mar 8; 446(7132): 153–158. doi: 10.1038/nature05610

PMCID:: PMC2712719

Abstract Article PDF–867K

Select item 18054718.

Distinct Priming Kinases Contribute to Differential Regulation of Collapsin Response Mediator Proteins by Glycogen Synthase Kinase-3 in Vivo

Adam R. Cole, Frédéric Causeret, Gokhan Yadirgi, C. James Hastie, Hilary McLauchlan, Edward J. McManus, Félix Hernández, Britta J. Eickholt, Margareta Nikolic, Calum Sutherland

J Biol Chem. Author manuscript; available in PMC 2007 Feb 27.

Published in final edited form as: J Biol Chem. 2006 Jun 16; 281(24): 16591–16598. Published online 2006 Apr 12. doi: 10.1074/jbc.M513344200