PMC Links for Protein (Select 21361095) - PMC

Result Filters

Links from Protein

Items: 14

Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 11699392.

Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres.

G Laible, A Wolf, R Dorn, G Reuter, C Nislow, A Lebersorger, D Popkin, L Pillus, T Jenuwein

EMBO J. 1997 Jun 2; 16(11): 3219–3232. doi: 10.1093/emboj/16.11.3219

PMCID:: PMC1169939

Summary PDF–680K

Select item 2313013.

Interaction of Vav with ENX-1, a putative transcriptional regulator of homeobox gene expression.

O Hobert, B Jallal, A Ullrich

Mol Cell Biol. 1996 Jun; 16(6): 3066–3073. doi: 10.1128/mcb.16.6.3066

PMCID:: PMC231301

Summary PDF–728K

Select item 63296964.

CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia

Woori Jang, Joonhong Park, Ahlm Kwon, Hayoung Choi, Jiyeon Kim, Gun Dong Lee, Eunhee Han, Dong Wook Jekarl, Hyojin Chae, Kyungja Han, Jae-Ho Yoon, Seok Lee, Nack-Gyun Chung, Bin Cho, Myungshin Kim, Yonggoo Kim

Exp Mol Med. 2019 Jan; 51(1): 4. Published online 2019 Jan 11. doi: 10.1038/s12276-018-0195-x

PMCID:: PMC6329696

Abstract Article PDF–1.3M

Select item 60715655.

Co-occurrence of a maternally inherited DNMT3A duplication and a paternally inherited pathogenic variant in EZH2 in a child with growth retardation and severe short stature: atypical Weaver syndrome or evidence of a DNMT3A dosage effect?

Katarzyna Polonis, Patrick R. Blackburn, Raul A. Urrutia, Gwen A. Lomberk, Teresa Kruisselbrink, Margot A. Cousin, Nicole J. Boczek, Nicole L. Hoppman, Dusica Babovic-Vuksanovic, Eric W. Klee, Pavel N. Pichurin

Cold Spring Harb Mol Case Stud. 2018 Aug; 4(4): a002899. doi: 10.1101/mcs.a002899

PMCID:: PMC6071565

Abstract Article PDF–5.8M

Select item 57970786.

The MRPS18-2 protein levels correlate with prostate tumor progression and it induces CXCR4-dependent migration of cancer cells

Muhammad Mushtaq, Lasse Jensen, Sabina Davidsson, Oleksandr V. Grygoruk, Ove Andrén, Vladimir Kashuba, Elena Kashuba

Sci Rep. 2018; 8: 2268. Published online 2018 Feb 2. doi: 10.1038/s41598-018-20765-8

PMCID:: PMC5797078

Abstract Article PDF–8.0M

Select item 57705907.

Prevalence of somatic mutations in patients with aplastic anemia using peripheral blood cfDNA as compared with BM

A Albitar, D Townsley, W Ma, I De Dios, V Funari, N S Young, M Albitar

Leukemia. 2018 Jan; 32(1): 227–229. Prepublished online 2017 Aug 23. Published online 2017 Sep 15. doi: 10.1038/leu.2017.271

PMCID:: PMC5770590

Article PDF–425K

Select item 50053148.

Somatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in Melanoma

Jessamy Tiffen, Stephen Wilson, Stuart J. Gallagher, Peter Hersey, Fabian V. Filipp

Neoplasia. 2016 Feb; 18(2): 121–132. Published online 2016 Feb 29. doi: 10.1016/j.neo.2016.01.003

PMCID:: PMC5005314

Abstract Article PDF–2.8M

Select item 47011959.

Sequencing Histone Modifying Enzymes Identifies UTX mutations in Acute Lymphoblastic Leukemia

BG Mar, L Bullinger, E Basu, K Schlis, LB Silverman, K Döhner, SA Armstrong

Leukemia. Author manuscript; available in PMC 2016 Jan 5.

Published in final edited form as: Leukemia. 2012 Aug; 26(8): 1881–1883. Published online 2012 Mar 1. doi: 10.1038/leu.2012.56

PMCID:: PMC4701195

Article PDF–826K

Select item 469497110.

Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes

Jessamy C. Tiffen, Dilini Gunatilake, Stuart J. Gallagher, Kavitha Gowrishankar, Anja Heinemann, Carleen Cullinane, Ken Dutton-Regester, Gulietta M. Pupo, Dario Strbenac, Jean Y. Yang, Jason Madore, Graham J. Mann, Nicholas K. Hayward, Grant A. McArthur, Fabian V. Filipp, Peter Hersey

Oncotarget. 2015 Sep 29; 6(29): 27023–27036. Published online 2015 Aug 12. doi: 10.18632/oncotarget.4809

PMCID:: PMC4694971

Abstract Article PDF–6.1M

Select item 456693311.

Histone lysine methyltransferases and demethylases in Plasmodium falciparum

Liwang Cui, Qi Fan, Long Cui, Jun Miao

Int J Parasitol. Author manuscript; available in PMC 2015 Sep 11.

Published in final edited form as: Int J Parasitol. 2008 Aug; 38(10): 1083–1097. Published online 2008 Jan 26. doi: 10.1016/j.ijpara.2008.01.002

PMCID:: PMC4566933

Abstract Article PDF–7.4M

Select item 391402312.

EZH2: biology, disease, and structure-based drug discovery

Jin-zhi Tan, Yan Yan, Xiao-xi Wang, Yi Jiang, H Eric Xu

Acta Pharmacol Sin. 2014 Feb; 35(2): 161–174. Published online 2013 Dec 23. doi: 10.1038/aps.2013.161

PMCID:: PMC3914023

Abstract Article PDF–5.7M

Select item 386855513.

Structural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET Domain

Stephen Antonysamy, Bradley Condon, Zhanna Druzina, Jeffrey B. Bonanno, Tarun Gheyi, Feiyu Zhang, Iain MacEwan, Aiping Zhang, Sheela Ashok, Logan Rodgers, Marijane Russell, John Gately Luz

PLoS One. 2013; 8(12): e84147. Published online 2013 Dec 19. doi: 10.1371/journal.pone.0084147