PMC Links for Protein (Select 332639873) - PMC

Select item 31052211.

Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial Enzymatic Activity

Sean C. Gay, Haoming Zhang, P. Ross Wilderman, Arthur G. Roberts, Tong Liu, Sheng Li, Hsia-lien Lin, Qinghai Zhang, Virgil L. Woods, Jr., C. David Stout, Paul F. Hollenberg, James R. Halpert

Biochemistry. Author manuscript; available in PMC 2012 Jun 7.

Published in final edited form as: Biochemistry. 2011 Jun 7; 50(22): 4903–4911. Published online 2011 May 13. doi: 10.1021/bi200482g

PMCID:: PMC3105221

Article PDF–947K

Select item 30057962.

Structures of Cytochrome P450 2B4 Complexed with the Antiplatelet Drugs Ticlopidine and Clopidogrel

Sean C. Gay, Arthur G. Roberts, Keiko Maekawa, Jyothi C. Talakad, Wen-Xu Hong, Qinghai Zhang, C. David Stout, James R. Halpert

Biochemistry. Author manuscript; available in PMC 2011 Oct 12.

Published in final edited form as: Biochemistry. 2010 Oct 12; 49(40): 8709–8720. Published online 2010 Sep 15. doi: 10.1021/bi100914z

PMCID:: PMC3005796

Article PDF–1.2M

Select item 29922923.

Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography

P. Ross Wilderman, Manish B. Shah, Tong Liu, Sheng Li, Simon Hsu, Arthur G. Roberts, David R. Goodlett, Qinghai Zhang, Virgil L. Woods, Jr, C. David Stout, James R. Halpert

J Biol Chem. 2010 Dec 3; 285(49): 38602–38611. Published online 2010 Sep 28. doi: 10.1074/jbc.M110.180646

PMCID:: PMC2992292

Article PDF–2.0M

Select item 27645334.

Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H–imidazole: ligand induced structural response through α-helical repositioning

Sean C. Gay, Ling Sun, Keiko Maekawa, James R. Halpert, C. David Stout

Biochemistry. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Biochemistry. 2009 Jun 9; 48(22): 4762–4771. doi: 10.1021/bi9003765

PMCID:: PMC2764533

Article PDF–7.1M

Select item 25668205.

Structural and Thermodynamic Consequences of 1-(4-Chlorophenyl)imidazole Binding to Cytochrome P450 2B4

Yonghong Zhao, Ling Sun, B. K. Muralidhara, Santosh Kumar, Mark A. White, C. David Stout, James R. Halpert

Biochemistry. Author manuscript; available in PMC 2008 Oct 16.

Published in final edited form as: Biochemistry. 2007 Oct 16; 46(41): 11559–11567. Published online 2007 Sep 22. doi: 10.1021/bi7011614

PMCID:: PMC2566820

Article PDF–4.6M

Select item 2637486.

An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution

Emily E. Scott, You Ai He, Michael R. Wester, Mark A. White, Christopher C. Chin, James R. Halpert, Eric F. Johnson, C. David Stout

Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23): 13196–13201. Published online 2003 Oct 16. doi: 10.1073/pnas.2133986100

PMCID:: PMC263748

Article PDF–715K

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