RecName: Full=Ragulator complex protein LAMTOR1; AltName: Full=Late en - Protein

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TRAF4-Mediated LAMTOR1 Ubiquitination Promotes mTORC1 Activation and Inhibits the Inflammation-Induced Colorectal Cancer Progression. [Adv Sci (Weinh). 2024]
TRAF4-Mediated LAMTOR1 Ubiquitination Promotes mTORC1 Activation and Inhibits the Inflammation-Induced Colorectal Cancer Progression.
Zhao L, Gao N, Peng X, Chen L, Meng T, Jiang C, Jin J, Zhang J, Duan Q, Tian H, et al. Adv Sci (Weinh). 2024 Mar; 11(12):e2301164. Epub 2024 Jan 16.
LAMTOR1 degrades MHC-II via the endocytic in hepatocellular carcinoma. [Carcinogenesis. 2022]
LAMTOR1 degrades MHC-II via the endocytic in hepatocellular carcinoma.
Wu B, Wang Q, Li B, Jiang M. Carcinogenesis. 2022 Dec 25; 43(11):1059-1070.
mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTOR. [Front Cell Neurosci. 2019]
mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTOR.
Sanders SS, De Simone FI, Thomas GM. Front Cell Neurosci. 2019; 13:115. Epub 2019 Apr 2.

RefSeq genomic sequence
See the genomic reference sequence for the LAMTOR1 gene (NG_021423.1).
RefSeq protein
See the reference protein sequence for ragulator complex protein LAMTOR1 (NP_060377.1).

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Q6IAA8 [Domain Mapping of Disease Mut...]
Q6IAA8
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
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Reactome [Reactome]
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reagent reviews [ExactAntigen/Labome]
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reagents [ExactAntigen/Labome]
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RecName: Full=Ragulator complex protein LAMTOR1; AltName: Full=Late endosomal/ly...
RecName: Full=Ragulator complex protein LAMTOR1; AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1; AltName: Full=Lipid raft adaptor protein p18; AltName: Full=Protein associated with DRMs and endosomes; AltName: Full=p27Kip1-releasing factor from RhoA; Short=p27RF-Rho
gi|125863645|sp|Q6IAA8.2|LTOR1_HUMA

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