RecName: Full=12S rRNA N(4)-cytidine methyltransferase METTL15; Short= - Protein

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The catalytic activity of methyltransferase METTL15 is dispensable for its role in mitochondrial ribosome biogenesis. [RNA Biol. 2024]
The catalytic activity of methyltransferase METTL15 is dispensable for its role in mitochondrial ribosome biogenesis.
Mutti CD, Van Haute L, Minczuk M. RNA Biol. 2024 Jan; 21(1):23-30. Epub 2024 Jun 24.
The human mitochondrial 12S rRNA m(4)C methyltransferase METTL15 is required for mitochondrial function. [J Biol Chem. 2020]
The human mitochondrial 12S rRNA m(4)C methyltransferase METTL15 is required for mitochondrial function.
Chen H, Shi Z, Guo J, Chang KJ, Chen Q, Yao CH, Haigis MC, Shi Y. J Biol Chem. 2020 Jun 19; 295(25):8505-8513. Epub 2020 May 5.
METTL15 interacts with the assembly intermediate of murine mitochondrial small ribosomal subunit to form m4C840 12S rRNA residue. [Nucleic Acids Res. 2020]
METTL15 interacts with the assembly intermediate of murine mitochondrial small ribosomal subunit to form m4C840 12S rRNA residue.
Laptev I, Shvetsova E, Levitskii S, Serebryakova M, Rubtsova M, Zgoda V, Bogdanov A, Kamenski P, Sergiev P, Dontsova O. Nucleic Acids Res. 2020 Aug 20; 48(14):8022-8034.

RefSeq protein isoforms
See 18 reference sequence protein isoforms for the METTL15 gene.

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A6NJ78 [Domain Mapping of Disease Mut...]
A6NJ78
Domain Mapping of Disease Mutations
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RecName: Full=12S rRNA N(4)-cytidine methyltransferase METTL15; Short=12S rRNA m...
RecName: Full=12S rRNA N(4)-cytidine methyltransferase METTL15; Short=12S rRNA m4C methyltransferase; AltName: Full=Methyltransferase 5 domain-containing protein 1; AltName: Full=Methyltransferase-like protein 15; Flags: Precursor
gi|160012249|sp|A6NJ78.1|MET15_HUMA

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