RecName: Full=Signal peptide peptidase-like 2C; Short=SPP-like 2C; Sho - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease. [Transl Psychiatry. 2021]
Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease.
He L, Loika Y, Park Y, Genotype Tissue Expression (GTEx) consortium, Bennett DA, Kellis M, Kulminski AM, Alzheimer’s Disease Neuroimaging Initiative. Transl Psychiatry. 2021 Feb 26; 11(1):146. Epub 2021 Feb 26.
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins. [EMBO Rep. 2019]
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, et al. EMBO Rep. 2019 Mar; 20(3). Epub 2019 Feb 7.
The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban. [EMBO Rep. 2019]
The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban.
Niemeyer J, Mentrup T, Heidasch R, Müller SA, Biswas U, Meyer R, Papadopoulou AA, Dederer V, Haug-Kröper M, Adamski V, et al. EMBO Rep. 2019 Mar; 20(3). Epub 2019 Feb 7.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Q8IUH8 [Domain Mapping of Disease Mut...]
Q8IUH8
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Signal peptide peptidase-like 2C; Short=SPP-like 2C; Short=SPPL2c;...
RecName: Full=Signal peptide peptidase-like 2C; Short=SPP-like 2C; Short=SPPL2c; AltName: Full=Intramembrane protease 5; Short=IMP-5; Flags: Precursor
gi|269849676|sp|Q8IUH8.3|SPP2C_HUMA

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein