RecName: Full=7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; - Protein

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Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans. [J Clin Invest. 2022]
Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans.
Zhong S, Chèvre R, Castaño Mayan D, Corlianò M, Cochran BJ, Sem KP, van Dijk TH, Peng J, Tan LJ, Hartimath SV, et al. J Clin Invest. 2022 Nov 1; 132(21). Epub 2022 Nov 1.
Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1. [Biol Chem. 2019]
Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1.
Fan L, Joseph JF, Durairaj P, Parr MK, Bureik M. Biol Chem. 2019 Apr 24; 400(5):625-628.
Single nucleotide polymorphism rs3732860 in the 3'-untranslated region of CYP8B1 gene is associated with gallstone disease in Han Chinese. [J Gastroenterol Hepatol. 2013]
Single nucleotide polymorphism rs3732860 in the 3'-untranslated region of CYP8B1 gene is associated with gallstone disease in Han Chinese.
Qin J, Han TQ, Yuan WT, Zhang J, Fei J, Jiang ZY, Niu ZM, Zhang KY, Hua Q, Cai XX, et al. J Gastroenterol Hepatol. 2013 Apr; 28(4):717-22.

RefSeq genomic sequence
See the genomic reference sequence for the CYP8B1 gene (NG_007970.1).
RefSeq protein
See the reference protein sequence for 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (NP_004382.2).

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Q9UNU6 [Domain Mapping of Disease Mut...]
Q9UNU6
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; AltName: F...
RecName: Full=7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; AltName: Full=7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase; AltName: Full=CYPVIIIB1; AltName: Full=Cytochrome P450 8B1; AltName: Full=Sterol 12-alpha-hydroxylase
gi|308153428|sp|Q9UNU6.2|CP8B1_HUMA

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