RecName: Full=E3 ubiquitin-protein ligase TTC3; AltName: Full=Protein - Protein

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An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons. [Neurobiol Aging. 2023]
An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons.
Cukier HN, Duarte CL, Laverde-Paz MJ, Simon SA, Van Booven DJ, Miyares AT, Whitehead PL, Hamilton-Nelson KL, Adams LD, Carney RM, et al. Neurobiol Aging. 2023 Nov; 131:182-195. Epub 2023 Jul 17.
TTC3-Mediated Protein Quality Control, A Potential Mechanism for Cognitive Impairment. [Cell Mol Neurobiol. 2022]
TTC3-Mediated Protein Quality Control, A Potential Mechanism for Cognitive Impairment.
Zhou X, Chen X, Hong T, Zhang M, Cai Y, Cui L. Cell Mol Neurobiol. 2022 Aug; 42(6):1659-1669. Epub 2021 Feb 27.
Derivation of stem cell line UMi028-A-2 containing a CRISPR/Cas9 induced Alzheimer's disease risk variant p.S1038C in the TTC3 gene. [Stem Cell Res. 2021]
Derivation of stem cell line UMi028-A-2 containing a CRISPR/Cas9 induced Alzheimer's disease risk variant p.S1038C in the TTC3 gene.
Laverde-Paz MJ, Nuytemans K, Wang L, Vance JM, Pericak-Vance MA, Dykxhoorn DM, Cukier HN. Stem Cell Res. 2021 Apr; 52:102258. Epub 2021 Feb 18.

RefSeq protein isoforms
See 10 reference sequence protein isoforms for the TTC3 gene.

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P53804 [Domain Mapping of Disease Mut...]
P53804
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=E3 ubiquitin-protein ligase TTC3; AltName: Full=Protein DCRR1; Alt...
RecName: Full=E3 ubiquitin-protein ligase TTC3; AltName: Full=Protein DCRR1; AltName: Full=RING finger protein 105; AltName: Full=RING-type E3 ubiquitin transferase TTC3; AltName: Full=TPR repeat protein D; AltName: Full=Tetratricopeptide repeat protein 3; Short=TPR repeat protein 3
gi|313104040|sp|P53804.2|TTC3_HUMAN

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