RecName: Full=Dual specificity mitogen-activated protein kinase kinase - Protein

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High-resolution structure discloses the potential for allosteric regulation of mitogen-activated protein kinase kinase 7. [Biochem Biophys Res Commun. 2017]
High-resolution structure discloses the potential for allosteric regulation of mitogen-activated protein kinase kinase 7.
Kinoshita T, Hashimoto T, Sogabe Y, Fukada H, Matsumoto T, Sawa M. Biochem Biophys Res Commun. 2017 Nov 4; 493(1):313-317. Epub 2017 Sep 7.
Rare variant of MAP2K7 is associated with increased risk of COPD in southern and eastern Chinese. [Respirology. 2017]
Rare variant of MAP2K7 is associated with increased risk of COPD in southern and eastern Chinese.
Qiu F, Li Y, Lu X, Xie C, Nong Q, Wu D, Chen J, Yang L, Zhou Y, Lu J. Respirology. 2017 May; 22(4):691-698. Epub 2017 Jan 24.
A crucial role of Cys218 in configuring an unprecedented auto-inhibition form of MAP2K7. [Biochem Biophys Res Commun. 2016]
A crucial role of Cys218 in configuring an unprecedented auto-inhibition form of MAP2K7.
Sogabe Y, Hashimoto T, Matsumoto T, Kirii Y, Sawa M, Kinoshita T. Biochem Biophys Res Commun. 2016 Apr 29; 473(2):476-81. Epub 2016 Mar 15.

RefSeq genomic sequence
See the genomic reference sequence for the MAP2K7 gene (NG_029438.2).
RefSeq protein isoforms
See 5 reference sequence protein isoforms for the MAP2K7 gene.

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Related structures

O14733 [Domain Mapping of Disease Mut...]
O14733
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Dual specificity mitogen-activated protein kinase kinase 7; Short=...
RecName: Full=Dual specificity mitogen-activated protein kinase kinase 7; Short=MAP kinase kinase 7; Short=MAPKK 7; AltName: Full=JNK-activating kinase 2; AltName: Full=MAPK/ERK kinase 7; Short=MEK 7; AltName: Full=Stress-activated protein kinase kinase 4; Short=SAPK kinase 4; Short=SAPKK-4; Short=SAPKK4; AltName: Full=c-Jun N-terminal kinase kinase 2; Short=JNK kinase 2; Short=JNKK 2
gi|6831583|sp|O14733.2|MP2K7_HUMAN

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