mediator complex subunit MED16 variant MED16_i24 [Homo sapiens]

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Mediator complex subunit 16 is down-regulated in papillary thyroid cancer, leading to increased transforming growth factor-β signaling and radioiodine resistance. [J Biol Chem. 2020]
Mediator complex subunit 16 is down-regulated in papillary thyroid cancer, leading to increased transforming growth factor-β signaling and radioiodine resistance.
Gao H, Bai P, Xiao L, Shen M, Yu Q, Lei Y, Huang W, Lin X, Zheng X, Wei T, et al. J Biol Chem. 2020 Jul 31; 295(31):10726-10740. Epub 2020 Jun 12.
Homozygous MED25 mutation implicated in eye-intellectual disability syndrome. [Hum Genet. 2015]
Homozygous MED25 mutation implicated in eye-intellectual disability syndrome.
Basel-Vanagaite L, Smirin-Yosef P, Essakow JL, Tzur S, Lagovsky I, Maya I, Pasmanik-Chor M, Yeheskel A, Konen O, Orenstein N, et al. Hum Genet. 2015 Jun; 134(6):577-87. Epub 2015 Mar 20.
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha. [Mol Cell. 2003]
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.
Wallberg AE, Yamamura S, Malik S, Spiegelman BM, Roeder RG. Mol Cell. 2003 Nov; 12(5):1137-49.

RefSeq protein isoforms
See 5 reference sequence protein isoforms for the MED16 gene.

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Protein