aminocarboxymuconate semialdehyde decarboxylase, isoform CRA_b [Homo s - Protein

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Protein 3D Structure

2.0 Angstroms X-ray crystal structure of human 2-amino-3-carboxymuconate-6-semialdehye decarboxylase

PDB: 4OFC

Source: Homo sapiens

Method: X-ray Diffraction

Resolution: 1.99 Å

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Articles about the ACMSD gene

A kynurenine pathway enzyme aminocarboxymuconate-semialdehyde decarboxylase may be involved in treatment-resistant depression, and baseline inflammation status of patients predicts treatment response: a pilot study. [J Neural Transm (Vienna). 2022]
A kynurenine pathway enzyme aminocarboxymuconate-semialdehyde decarboxylase may be involved in treatment-resistant depression, and baseline inflammation status of patients predicts treatment response: a pilot study.
Yilmaz NS, Sen B, Karadag RF, Aslan S, Ekmekci Ertek I, Bozkurt A, Cicek S, Bolu A, Ucar H, Kocak C, et al. J Neural Transm (Vienna). 2022 Dec; 129(12):1513-1526. Epub 2022 Nov 5.
An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation. [Transl Psychiatry. 2016]
An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation.
Brundin L, Sellgren CM, Lim CK, Grit J, Pålsson E, Landén M, Samuelsson M, Lundgren K, Brundin P, Fuchs D, et al. Transl Psychiatry. 2016 Aug 2; 6(8):e865. Epub 2016 Aug 2.
The ACMSD gene, involved in tryptophan metabolism, is mutated in a family with cortical myoclonus, epilepsy, and parkinsonism. [J Mol Med (Berl). 2013]
The ACMSD gene, involved in tryptophan metabolism, is mutated in a family with cortical myoclonus, epilepsy, and parkinsonism.
Martí-Massó JF, Bergareche A, Makarov V, Ruiz-Martinez J, Gorostidi A, López de Munain A, Poza JJ, Striano P, Buxbaum JD, Paisán-Ruiz C. J Mol Med (Berl). 2013 Dec; 91(12):1399-406. Epub 2013 Aug 20.

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Reference sequence information

RefSeq protein isoforms
See 15 reference sequence protein isoforms for the ACMSD gene.

More about the ACMSD gene

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in ...

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aminocarboxymuconate semialdehyde decarboxylase, isoform CRA_b [Homo sapiens]

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Articles about the ACMSD gene

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