isoleucine--tRNA ligase, cytoplasmic isoform 2 [Homo sapiens]

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New evidence for association of recessive IARS gene mutations with hepatopathy, hypotonia, intellectual disability and growth retardation. [Clin Genet. 2017]
New evidence for association of recessive IARS gene mutations with hepatopathy, hypotonia, intellectual disability and growth retardation.
Smigiel R, Biela M, Biernacka A, Stembalska A, Sasiadek M, Kosinska J, Rydzanicz M, Ploski R. Clin Genet. 2017 Dec; 92(6):671-673. Epub 2017 Oct 19.
Bi-allelic IARS mutations in a child with intra-uterine growth retardation, neonatal cholestasis, and mild developmental delay. [Clin Genet. 2017]
Bi-allelic IARS mutations in a child with intra-uterine growth retardation, neonatal cholestasis, and mild developmental delay.
Orenstein N, Weiss K, Oprescu SN, Shapira R, Kidron D, Vanagaite-Basel L, Antonellis A, Muenke M. Clin Genet. 2017 Jun; 91(6):913-917. Epub 2017 Feb 22.
Mapping and exome sequencing identifies a mutation in the IARS gene as the cause of hereditary perinatal weak calf syndrome. [PLoS One. 2013]
Mapping and exome sequencing identifies a mutation in the IARS gene as the cause of hereditary perinatal weak calf syndrome.
Hirano T, Kobayashi N, Matsuhashi T, Watanabe D, Watanabe T, Takasuga A, Sugimoto M, Sugimoto Y. PLoS One. 2013; 8(5):e64036. Epub 2013 May 21.

RefSeq genomic sequence
See the genomic reference sequence for the IARS1 gene (NG_051498.1).
RefSeq mRNA
See reference mRNA sequence for the IARS1 gene (NM_001374300.1).

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Protein