complement component C9 preproprotein [Homo sapiens]

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The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade. [Hum Mol Genet. 2021]
The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade.
McMahon O, Hallam TM, Patel S, Harris CL, Menny A, Zelek WM, Widjajahakim R, Java A, Cox TE, Tzoumas N, et al. Hum Mol Genet. 2021 Jun 17; 30(13):1188-1199.
Functional analyses of rare genetic variants in complement component C9 identified in patients with age-related macular degeneration. [Hum Mol Genet. 2018]
Functional analyses of rare genetic variants in complement component C9 identified in patients with age-related macular degeneration.
Kremlitzka M, Geerlings MJ, de Jong S, Bakker B, Nilsson SC, Fauser S, Hoyng CB, de Jong EK, den Hollander AI, Blom AM. Hum Mol Genet. 2018 Aug 1; 27(15):2678-2688.
Hepatitis C virus suppresses C9 complement synthesis and impairs membrane attack complex function. [J Virol. 2013]
Hepatitis C virus suppresses C9 complement synthesis and impairs membrane attack complex function.
Kim H, Meyer K, Di Bisceglie AM, Ray R. J Virol. 2013 May; 87(10):5858-67. Epub 2013 Mar 13.

RefSeq genomic sequence
See the genomic reference sequence for the C9 gene (NG_009894.1).
RefSeq mRNA
See reference mRNA sequence for the C9 gene (NM_001737.5).

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NP_001728 [Domain Mapping of Disease Mut...]
NP_001728
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Find Quality Antibodies [GeneTex Inc]
Find Quality Antibodies
GeneTex Inc

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