cyclic AMP-dependent transcription factor ATF-4 [Homo sapiens]

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Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control. [Cell Rep. 2024]
Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control.
Smirnova AM, Hronová V, Mohammad MP, Herrmannová A, Gunišová S, Petráčková D, Halada P, Coufal Š, Świrski M, Rendleman J, et al. Cell Rep. 2024 Apr 23; 43(4):113976. Epub 2024 Mar 19.
ATF4 in cellular stress, ferroptosis, and cancer. [Arch Toxicol. 2024]
ATF4 in cellular stress, ferroptosis, and cancer.
Tang H, Kang R, Liu J, Tang D. Arch Toxicol. 2024 Apr; 98(4):1025-1041. Epub 2024 Feb 21.
Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs. [PLoS Genet. 2023]
Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs.
Örd T, Örd D, Adler P, Örd T. PLoS Genet. 2023 Oct; 19(10):e1011014. Epub 2023 Oct 31.

RefSeq mRNA
See reference mRNA sequence for the ATF4 gene (NM_182810.3).
RefSeq protein isoforms
See 4 reference sequence protein isoforms for the ATF4 gene.

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NP_877962 [Domain Mapping of Disease Mut...]
NP_877962
Domain Mapping of Disease Mutations
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Ensembl
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
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OncoMX cancer biomarker resource
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reagents
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