RecName: Full=Tyrosine-protein kinase JAK2; AltName: Full=Janus kinase - Protein

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Molecular basis of JAK2 activation in erythropoietin receptor and pathogenic JAK2 signaling. [Sci Adv. 2024]
Molecular basis of JAK2 activation in erythropoietin receptor and pathogenic JAK2 signaling.
Abraham BG, Haikarainen T, Vuorio J, Girych M, Virtanen AT, Kurttila A, Karathanasis C, Heilemann M, Sharma V, Vattulainen I, et al. Sci Adv. 2024 Mar 8; 10(10):eadl2097. Epub 2024 Mar 8.
Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche. [Stem Cell Reports. 2024]
Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche.
Flosdorf N, Böhnke J, de Toledo MAS, Lutterbach N, Lerma VG, Graßhoff M, Olschok K, Gupta S, Tharmapalan V, Schmitz S, et al. Stem Cell Reports. 2024 Feb 13; 19(2):224-238. Epub 2024 Jan 25.
Identification and validation of the association of Janus kinase 2 mutations with the response to immune checkpoint inhibitor therapy. [Inflamm Res. 2024]
Identification and validation of the association of Janus kinase 2 mutations with the response to immune checkpoint inhibitor therapy.
Chen P, Long J, Zhang J, Xie F, Wu W, Tian Z, Zhang S, Yu K. Inflamm Res. 2024 Feb; 73(2):263-276. Epub 2024 Jan 10.

RefSeq genomic sequence
See the genomic reference sequence for the JAK2 gene (NG_009904.1).
RefSeq protein isoforms
See 7 reference sequence protein isoforms for the JAK2 gene.

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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
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reagents [ExactAntigen/Labome]
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Protein