RecName: Full=5-formyltetrahydrofolate cyclo-ligase; AltName: Full=5,1 - Protein

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5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination. [Mol Genet Metab. 2018]
5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination.
Rodan LH, Qi W, Ducker GS, Demirbas D, Laine R, Yang E, Walker MA, Eichler F, Rabinowitz JD, Anselm I, et al. Mol Genet Metab. 2018 Sep; 125(1-2):118-126. Epub 2018 Jun 15.
The impact of 5,10-methenyltetrahydrofolate synthetase polymorphism on diabetic nephropathy in the Taiwanese population. [Genet Test Mol Biomarkers. 2012]
The impact of 5,10-methenyltetrahydrofolate synthetase polymorphism on diabetic nephropathy in the Taiwanese population.
Lin CJ, Wen MJ, Hung YJ, Pei D, Kuo SW, Hsieh CH. Genet Test Mol Biomarkers. 2012 Feb; 16(2):142-5. Epub 2011 Sep 6.
Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies. [BMC Med Genet. 2008]
Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies.
Kottgen A, Kao WH, Hwang SJ, Boerwinkle E, Yang Q, Levy D, Benjamin EJ, Larson MG, Astor BC, Coresh J, et al. BMC Med Genet. 2008 Jun 3; 9:49. Epub 2008 Jun 3.

RefSeq genomic sequence
See the genomic reference sequence for the MTHFS gene (NG_029243.1).
RefSeq protein isoforms
See 2 reference sequence protein isoforms for the MTHFS gene.

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Transcript/Protein Information [PANTHER Classification System]
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Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
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Protein