RecName: Full=GDNF family receptor alpha-1; Short=GDNF receptor alpha- - Protein

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Biallelic loss-of-function variants of GFRA1 cause lethal bilateral renal agenesis. [Eur J Med Genet. 2022]
Biallelic loss-of-function variants of GFRA1 cause lethal bilateral renal agenesis.
Al-Shamsi B, Al-Kasbi G, Al-Kindi A, Bruwer Z, Al-Kharusi K, Al-Maawali A. Eur J Med Genet. 2022 Jan; 65(1):104376. Epub 2021 Nov 1.
Deficiency of GFRα1 promotes hepatocellular carcinoma progression but enhances oxaliplatin-mediated anti-tumor efficacy. [Pharmacol Res. 2021]
Deficiency of GFRα1 promotes hepatocellular carcinoma progression but enhances oxaliplatin-mediated anti-tumor efficacy.
Zhu H, Huang M, Luo J, Ji X, Liu Q. Pharmacol Res. 2021 Oct; 172:105815. Epub 2021 Aug 13.
Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predicts metastasis of colorectal cancer. [PLoS Genet. 2020]
Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predicts metastasis of colorectal cancer.
Dong Z, Dai L, Zhang Y, Fang C, Shi G, Chen Y, Li J, Wang Q, Fu J, Yu Y, et al. PLoS Genet. 2020 Nov; 16(11):e1009159. Epub 2020 Nov 11.

RefSeq genomic sequence
See the genomic reference sequence for the GFRA1 gene (NG_050620.1).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the GFRA1 gene.

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Transcript/Protein Information [PANTHER Classification System]
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Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
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Protein