RecName: Full=Mediator of RNA polymerase II transcription subunit 27; - Protein

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Biallelic MED27 variants lead to variable ponto-cerebello-lental degeneration with movement disorders. [Brain. 2023]
Biallelic MED27 variants lead to variable ponto-cerebello-lental degeneration with movement disorders.
Maroofian R, Kaiyrzhanov R, Cali E, Zamani M, Zaki MS, Ferla M, Tortora D, Sadeghian S, Saadi SM, Abdullah U, et al. Brain. 2023 Dec 1; 146(12):5031-5043.
Knockdown of mediator complex subunit 27 suppresses gastric cancer cell metastasis and angiogenesis via Wnt/β-catenin pathway. [Tissue Cell. 2022]
Knockdown of mediator complex subunit 27 suppresses gastric cancer cell metastasis and angiogenesis via Wnt/β-catenin pathway.
Han X, Liu H, Tang X, Zhao Y. Tissue Cell. 2022 Dec; 79:101973. Epub 2022 Nov 9.
MED27 Variants Cause Developmental Delay, Dystonia, and Cerebellar Hypoplasia. [Ann Neurol. 2021]
MED27 Variants Cause Developmental Delay, Dystonia, and Cerebellar Hypoplasia.
Meng L, Isohanni P, Shao Y, Graham BH, Hickey SE, Brooks S, Suomalainen A, Joset P, Steindl K, Rauch A, et al. Ann Neurol. 2021 Apr; 89(4):828-833. Epub 2021 Feb 8.

RefSeq protein isoforms
See 9 reference sequence protein isoforms for the MED27 gene.

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Q6P2C8 [Domain Mapping of Disease Mut...]
Q6P2C8
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Protein