RecName: Full=Inactive rhomboid protein 2; Short=iRhom2; AltName: Full - Protein

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RHBDF2 is correlated with immune infiltrates in hepatocellular carcinoma and may have potential as a biomarker. [FEBS Open Bio. 2023]
RHBDF2 is correlated with immune infiltrates in hepatocellular carcinoma and may have potential as a biomarker.
Gong H, Xie H, Huangfu Z, Zhang S, Tang Y, Xiao M, Li M, Wang Y. FEBS Open Bio. 2023 May; 13(5):881-897. Epub 2023 Apr 5.
iRhom2 regulates ERBB signalling to promote KRAS-driven tumour growth of lung cancer cells. [J Cell Sci. 2022]
iRhom2 regulates ERBB signalling to promote KRAS-driven tumour growth of lung cancer cells.
Sieber B, Lu F, Stribbling SM, Grieve AG, Ryan AJ, Freeman M. J Cell Sci. 2022 Sep 1; 135(17). Epub 2022 Sep 8.
The Threshold Effect: Lipopolysaccharide-Induced Inflammatory Responses in Primary Macrophages Are Differentially Regulated in an iRhom2-Dependent Manner. [Front Cell Infect Microbiol. 2...]
The Threshold Effect: Lipopolysaccharide-Induced Inflammatory Responses in Primary Macrophages Are Differentially Regulated in an iRhom2-Dependent Manner.
Skurski J, Dixit G, Blobel CP, Issuree PD, Maretzky T. Front Cell Infect Microbiol. 2020; 10:620392. Epub 2021 Jan 29.

RefSeq genomic sequence
See the genomic reference sequence for the RHBDF2 gene (NG_032852.1).
RefSeq protein isoforms
See 40 reference sequence protein isoforms for the RHBDF2 gene.

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Q6PJF5 [Domain Mapping of Disease Mut...]
Q6PJF5
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
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Reactome [Reactome]
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