RecName: Full=Protein unc-45 homolog A; Short=Unc-45A; AltName: Full=G - Protein

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Aagenaes syndrome/lymphedema cholestasis syndrome 1 is caused by a founder variant in the 5'-untranslated region of UNC45A. [J Hepatol. 2023]
Aagenaes syndrome/lymphedema cholestasis syndrome 1 is caused by a founder variant in the 5'-untranslated region of UNC45A.
Almaas R, Atneosen-Åsegg M, Ytre-Arne ME, Melheim M, Sorte HS, Cízková D, Reims HM, Bezrouk A, Harrison SP, Strand J, et al. J Hepatol. 2023 Oct; 79(4):945-954. Epub 2023 Jun 14.
UNC-45A breaks the microtubule lattice independently of its effects on non-muscle myosin II. [J Cell Sci. 2021]
UNC-45A breaks the microtubule lattice independently of its effects on non-muscle myosin II.
Habicht J, Mooneyham A, Hoshino A, Shetty M, Zhang X, Emmings E, Yang Q, Coombes C, Gardner MK, Bazzaro M. J Cell Sci. 2021 Jan 8; 134(1). Epub 2021 Jan 8.
UNC-45A Is a Novel Microtubule-Associated Protein and Regulator of Paclitaxel Sensitivity in Ovarian Cancer Cells. [Mol Cancer Res. 2019]
UNC-45A Is a Novel Microtubule-Associated Protein and Regulator of Paclitaxel Sensitivity in Ovarian Cancer Cells.
Mooneyham A, Iizuka Y, Yang Q, Coombes C, McClellan M, Shridhar V, Emmings E, Shetty M, Chen L, Ai T, et al. Mol Cancer Res. 2019 Feb; 17(2):370-383. Epub 2018 Oct 15.

RefSeq genomic sequence
See the genomic reference sequence for the UNC45A gene (NG_061633.1).
RefSeq protein isoforms
See 9 reference sequence protein isoforms for the UNC45A gene.

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Q9H3U1 [Domain Mapping of Disease Mut...]
Q9H3U1
Domain Mapping of Disease Mutations
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Protein