calcium-independent phospholipase A2-gamma isoform X1 [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer. [Breast Cancer Res. 2023]
Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer.
Tan Z, Deme P, Boyapati K, Claes BSR, Duivenvoorden AAM, Heeren RMA, Tressler CM, Haughey NJ, Glunde K. Breast Cancer Res. 2023 Nov 28; 25(1):148. Epub 2023 Nov 28.
A neurodegenerative mitochondrial disease phenotype due to biallelic loss-of-function variants in PNPLA8 encoding calcium-independent phospholipase A2γ. [Am J Med Genet A. 2018]
A neurodegenerative mitochondrial disease phenotype due to biallelic loss-of-function variants in PNPLA8 encoding calcium-independent phospholipase A2γ.
Shukla A, Saneto RP, Hebbar M, Mirzaa G, Girisha KM. Am J Med Genet A. 2018 May; 176(5):1232-1237.
Heart failure-induced activation of phospholipase iPLA(2)γ generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore. [J Biol Chem. 2018]
Heart failure-induced activation of phospholipase iPLA(2)γ generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore.
Moon SH, Liu X, Cedars AM, Yang K, Kiebish MA, Joseph SM, Kelley J, Jenkins CM, Gross RW. J Biol Chem. 2018 Jan 5; 293(1):115-129. Epub 2017 Nov 20.

RefSeq genomic sequence
See the genomic reference sequence for the PNPLA8 gene (NG_042172.1).
RefSeq mRNA
See reference mRNA sequence for the PNPLA8 gene (XM_011516274.4).

BioProject
Proteins related to BioProjects
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
SNP
Related SNPs

Ensembl [Ensembl]
Ensembl
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

calcium-independent phospholipase A2-gamma isoform X1 [Homo sapiens]
calcium-independent phospholipase A2-gamma isoform X1 [Homo sapiens]
gi|767947955|ref|XP_011514576.1|

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein