bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN isoform X1 [ - Protein

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WRN exonuclease imparts high fidelity on translesion synthesis by Y family DNA polymerases. [Genes Dev. 2024]
WRN exonuclease imparts high fidelity on translesion synthesis by Y family DNA polymerases.
Yoon JH, Sellamuthu K, Prakash L, Prakash S. Genes Dev. 2024 Apr 17; 38(5-6):213-232. Epub 2024 Apr 17.
Comprehensive mapping of cell fates in microsatellite unstable cancer cells supports dual targeting of WRN and ATR. [Genes Dev. 2023]
Comprehensive mapping of cell fates in microsatellite unstable cancer cells supports dual targeting of WRN and ATR.
Zong D, Koussa NC, Cornwell JA, Pankajam AV, Kruhlak MJ, Wong N, Chari R, Cappell SD, Nussenzweig A. Genes Dev. 2023 Oct 1; 37(19-20):913-928. Epub 2023 Nov 6.
Werner syndrome protein works as a dimer for unwinding and replication fork regression. [Nucleic Acids Res. 2023]
Werner syndrome protein works as a dimer for unwinding and replication fork regression.
Shin S, Hyun K, Lee J, Joo D, Kulikowicz T, Bohr VA, Kim J, Hohng S. Nucleic Acids Res. 2023 Jan 11; 51(1):337-348.

RefSeq genomic sequence
See the genomic reference sequence for the WRN gene (NG_008870.1).
RefSeq mRNA
See reference mRNA sequence for the WRN gene (XM_011544639.4).
RefSeq protein isoforms
See 5 reference sequence protein isoforms for the WRN gene.

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Protein