RecName: Full=Cyclic GMP-AMP synthase; Short=cGAMP synthase; Short=cGA - Protein

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Arginine methylation-dependent cGAS stability promotes non-small cell lung cancer cell proliferation. [Cancer Lett. 2024]
Arginine methylation-dependent cGAS stability promotes non-small cell lung cancer cell proliferation.
Liu X, Zheng W, Zhang L, Cao Z, Cong X, Hu Q, Hou J, Jin X, Yuan Q, Lin L, et al. Cancer Lett. 2024 Apr 1; 586:216707. Epub 2024 Feb 7.
cGAS Mediates the Inflammatory Responses of Human Microglial Cells to Genotoxic DNA Damage. [Inflammation. 2024]
cGAS Mediates the Inflammatory Responses of Human Microglial Cells to Genotoxic DNA Damage.
Suptela AJ, Radwan Y, Richardson C, Yan S, Afonin KA, Marriott I. Inflammation. 2024 Apr; 47(2):822-836. Epub 2023 Dec 26.
Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity. [Cancer Cell. 2023]
Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity.
Fang L, Hao Y, Yu H, Gu X, Peng Q, Zhuo H, Li Y, Liu Z, Wang J, Chen Y, et al. Cancer Cell. 2023 Jun 12; 41(6):1118-1133.e12. Epub 2023 Jun 1.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the CGAS gene.

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Q8N884 [Domain Mapping of Disease Mut...]
Q8N884
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
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reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Cyclic GMP-AMP synthase; Short=cGAMP synthase; Short=cGAS; Short=h...
RecName: Full=Cyclic GMP-AMP synthase; Short=cGAMP synthase; Short=cGAS; Short=h-cGAS; AltName: Full=2'3'-cGAMP synthase; AltName: Full=Mab-21 domain-containing protein 1
gi|68565218|sp|Q8N884.2|CGAS_HUMAN

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