RecName: Full=Aldo-keto reductase family 1 member C2; AltName: Full=3- - Protein

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Function, drug resistance and prognostic effect of AKR1C2 in human cancer. [Neoplasma. 2023]
Function, drug resistance and prognostic effect of AKR1C2 in human cancer.
Wang Z, Feng Y, Song J, Sun D, Zhang YY. Neoplasma. 2023 Jun; 70(3):319-332.
Comprehensive analysis regarding the prognostic significance of downregulated ferroptosis-related gene AKR1C2 in gastric cancer and its underlying roles in immune response. [PLoS One. 2023]
Comprehensive analysis regarding the prognostic significance of downregulated ferroptosis-related gene AKR1C2 in gastric cancer and its underlying roles in immune response.
Liu W, Zhang F, Yang K, Yan Y. PLoS One. 2023; 18(1):e0280989. Epub 2023 Jan 26.
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway. [J Cell Mol Med. 2020]
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway.
Zhang ZF, Huang TJ, Zhang XK, Xie YJ, Lin ST, Luo FF, Meng DF, Hu H, Wang J, Peng LX, et al. J Cell Mol Med. 2020 Sep; 24(17):9999-10012. Epub 2020 Jul 17.

RefSeq genomic sequence
See the genomic reference sequence for the AKR1C2 gene (NG_031852.1).
RefSeq protein isoforms
See 9 reference sequence protein isoforms for the AKR1C2 gene.

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Related structures

P52895 [Domain Mapping of Disease Mut...]
P52895
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Aldo-keto reductase family 1 member C2; AltName: Full=3-alpha-HSD3...
RecName: Full=Aldo-keto reductase family 1 member C2; AltName: Full=3-alpha-HSD3; AltName: Full=Chlordecone reductase homolog HAKRD; AltName: Full=Dihydrodiol dehydrogenase 2; Short=DD-2; Short=DD2; AltName: Full=Dihydrodiol dehydrogenase/bile acid-binding protein; Short=DD/BABP; AltName: Full=Type III 3-alpha-hydroxysteroid dehydrogenase
gi|20532374|sp|P52895.3|AK1C2_HUMAN

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