Protein Family Models for Protein (Select 1118007051) - Protein Family Models

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Links from Protein

Items: 6

Select item 4173421.

Proteins containing this zinc ribbon domain at the C-terminus include the RNA-guided DNA endonuclease TnpB, found as an accessory protein (that is, not required for transposition) in many IS (insertion sequence) elements.

Date:: 2024-08-14

Family Accession:: NF018933.5
Method:: HMM

Select item 3946612.

new record, indexing in progress

Family Accession:

Select item 3529573.

new record, indexing in progress

Family Accession:

Select item 3400634.

transposase

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism, may belong to the IS200/IS605 family

Date:: 2022-08-08

Family Accession:: 17609906
Method:: Sparcle

Select item 3356035.

RNA-guided endonuclease TnpB family protein

This family includes RNA-guided endonuclease TnpB from IS200/IS605 family elements (NF038281) and IS607 family elements (NF038280), but also many additional proteins. It exhibits homolog to or actually includes some CRISPR-associated (Cas) proteins such as the type V CRISPR-associated protein C2c8. For a long time, TnpB proteins were described as accessory proteins in IS (insertion sequence) elements, present as one of just one or two proteins encoded in the element but not necessary for transposition. The programmable RNA-guided endonuclease TnpB proteins may provide a CRISPR-like, widespread form of phage defense by RNA-guided DNA degradation.