Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
GNAT family N-acetyltransferase
This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. [1]. 9175471. GCN5-related histone N-acetyltransferases belong to a diverse. superfamily that includes the yeast SPT10 protein.. Neuwald AF, Landsman D;. Trends Biochem Sci 1997;22:154-155.. [2]. 11893502. A second catalytic domain in the Elp3 histone. acetyltransferases: a candidate for histone demethylase. activity?.. Chinenov Y;. Trends Biochem Sci 2002;27:115-117. (from Pfam)
N-acetyltransferase
This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterised by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule. [1]. 18709443. Structure of an acetyl-CoA binding protein from Staphylococcus. aureus representing a novel subfamily of GCN5-related. N-acetyltransferase-like proteins.. Cort JR, Ramelot TA, Murray D, Acton TB, Ma LC, Xiao R,. Montelione GT, Kennedy MA;. J Struct Funct Genomics. 2008;9:7-20. (from Pfam)
This domain catalyses N-acetyltransferase reactions. (from Pfam)
This family contains proteins with N-acetyltransferase functions. (from Pfam)
The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47 (Swiss:Q9VR51). This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands. (from Pfam)
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on