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Metalloenzyme superfamily
This family includes phosphopentomutase Swiss:P07651 and 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, Swiss:P37689. This family is also related to Pfam:PF00245 [1]. The alignment contains the most conserved residues that are probably involved in metal binding and catalysis. [1]. 10082381. A superfamily of metalloenzymes unifies phosphopentomutase and. cofactor- independent phosphoglycerate mutase with alkaline. phosphatases and sulfatases.. Galperin MY, Bairoch A, Koonin EV;. Protein Sci 1998;7:1829-1835. (from Pfam)
alkaline phosphatase
alkaline phosphatase is a zinc and magnesium dependent non-specific phosphomonoesterase that catalyzes the hydrolysis of phosphate monoesters at basic pH values
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