Protein Family Models

This is a family of prokaryotic toxin-antitoxin (TA) systems inhibitors, found in Podoviridae such as Enterobacteria phage T7. Family members such as Gene product 4.5 have been shown to neutralize TA-system-mediated abortive infection by inhibiting the Lon protease activity, thus preventing antitoxin degradation and toxin activation [1]. [1]. 23478446. Discovery of functional toxin/antitoxin systems in bacteria by. shotgun cloning.. Sberro H, Leavitt A, Kiro R, Koh E, Peleg Y, Qimron U, Sorek R;. Mol Cell. 2013;50:136-148. (from Pfam)

Date:

2024-07-08

PHA00446 family protein

Date:

2017-03-02