Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

P - Inorganic ion transport and metabolism

Download

Stats

COG
definitions
Organims Proteins Median Protein
Length
Genes
243 2,293 349,888 327.0 229
Organism Protein COG Cat Annotation
647 1228 COG0003 P Anion-transporting ATPase, ArsA/GET3 family
1728 2790 COG0004 P Ammonia channel protein AmtB
1328 2373 COG0025 P NhaP-type Na+/H+ or K+/H+ antiporter
1382 2159 COG0038 P H+/Cl- antiporter ClcA
1859 2797 COG0053 P Divalent metal cation (Fe/Co/Zn/Cd) efflux pump
1329 1883 COG0155 P Sulfite reductase, beta subunit (hemoprotein)
1649 2595 COG0168 P Trk-type K+ transport system, membrane component
1905 3302 COG0226 P ABC-type phosphate transport system, periplasmic component
1667 2244 COG0239 D P Fluoride ion exporter CrcB/FEX, affects chromosome condensation
1640 2530 COG0288 P Carbonic anhydrase
1469 2012 COG0306 P Phosphate/sulfate permease
627 805 COG0310 P ABC-type Co2+ transport system, permease component
628 812 COG0369 F P Flavoprotein (flavin reductase) subunit CysJ of sulfite and N-hydroxylaminopurine reductases
1330 1944 COG0370 P Fe2+ transporter FeoB
917 1016 COG0376 P Catalase (peroxidase I)
454 540 COG0387 P Cation (Ca2+/Na+/K+)/H+ antiporter ChaA
617 630 COG0390 P ABC-type iron transport system FetAB, permease component
1174 1674 COG0428 P Zinc transporter ZupT
1474 8269 COG0444 E P ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
1472 3051 COG0474 P Magnesium-transporting ATPase (P-type)
1682 3384 COG0475 P Kef-type K+ transport system, membrane component KefB
846 2343 COG0477 G E P R MFS family permease, includes anhydromuropeptide permease AmpG
491 577 COG0490 T P K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) domain
1152 1419 COG0529 P Adenylylsulfate kinase or related kinase
1232 1840 COG0530 P Ca2+/Na+ antiporter
830 1020 COG0555 P ABC-type sulfate transport system, permease component
1950 5434 COG0569 T P Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain
1726 2082 COG0573 P ABC-type phosphate transport system, permease component
1828 2237 COG0581 P ABC-type phosphate transport system, permease component
1722 2711 COG0598 P Mg2+ and Co2+ transporter CorA
1516 5902 COG0600 P ABC-type nitrate/sulfonate/bicarbonate transport system, permease component
1824 8432 COG0601 E P ABC-type dipeptide/oligopeptide/nickel transport system, permease component
1837 2363 COG0605 P Superoxide dismutase
2030 8655 COG0607 P Rhodanese-related sulfurtransferase
1748 4852 COG0609 P ABC-type Fe3+-siderophore transport system, permease component
1806 5468 COG0614 P ABC-type Fe3+-hydroxamate transport system, periplasmic component
1213 2337 COG0651 C P Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit
1505 3234 COG0659 P Sulfate permease or related transporter, MFS superfamily, contains STAS domain
1167 1309 COG0670 P Integral membrane protein YbhL, putative Ca2+ regulator, Bax inhibitor (BI-1)/TMBIM family
613 687 COG0672 P High-affinity Fe2+/Pb2+ permease
1805 2479 COG0704 P Phosphate uptake regulator PhoU
1667 6898 COG0715 P ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component
1502 2092 COG0725 P ABC-type molybdate transport system, periplasmic Mo-binding protein ModA
1918 5465 COG0730 P Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family
2049 4946 COG0735 P Fe2+ or Zn2+ uptake regulation protein Fur/Zur
444 474 COG0748 P Putative heme iron utilization protein, contains PNPOx domain
995 1581 COG0753 P Catalase
1119 1395 COG0798 P Arsenite efflux pump ArsB, ACR3 family
1607 2459 COG0803 P ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA
1526 1648 COG0855 P Polyphosphate kinase
1341 2342 COG0861 P Tellurite resistance membrane protein TerC
960 1186 COG1006 P Multisubunit Na+/H+ antiporter, MnhC subunit
1362 2061 COG1055 P Na+/H+ antiporter NhaD or related arsenite permease
1728 3121 COG1108 P ABC-type Mn2+/Zn2+ transport system, permease component
1573 5440 COG1116 P ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component
1848 2512 COG1117 P ABC-type phosphate transport system, ATPase component
792 980 COG1118 P ABC-type sulfate/molybdate transport systems, ATPase component
696 757 COG1119 P ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA
1754 4229 COG1120 H P ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component
1702 2634 COG1121 P ABC-type Mn2+/Zn2+ transport system, ATPase component
1206 3024 COG1122 P R Energy-coupling factor transporter ATP-binding protein EcfA2
464 690 COG1124 E P ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
430 498 COG1140 C P Nitrate reductase beta subunit
1810 8376 COG1173 E P ABC-type dipeptide/oligopeptide/nickel transport system, permease component
1233 2298 COG1178 P ABC-type Fe3+ transport system, permease component
954 1076 COG1218 P 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase
982 1553 COG1226 P Voltage-gated potassium channel Kch
1365 2111 COG1230 P Co/Zn/Cd efflux system component
1579 2350 COG1235 P Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase
1961 4447 COG1253 T P Mg2+ efflux pump MpfA, contains CBS pair and CorC-HlyC domains, TlyC/UPF0053 family
506 666 COG1276 P Putative copper export protein
905 1216 COG1283 P Na+/phosphate symporter
1002 1291 COG1285 P Magnesium uptake protein YhiD/SapB, involved in acid resistance
887 1102 COG1320 P Multisubunit Na+/H+ antiporter, MnhG subunit
833 851 COG1324 P Divalent cation tolerance protein CutA
452 679 COG1348 H P Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC
851 1004 COG1392 P Phosphate transport regulator YkaA, distantly related to PhoU, UPF0111/DUF47 family
1424 2673 COG1393 P Arsenate reductase or related protein, glutaredoxin family
459 690 COG1416 P Intracellular sulfur oxidation protein, DsrE/DsrF family
887 1583 COG1464 P ABC-type metal ion transport system, periplasmic component/surface antigen
1609 1642 COG1496 P Copper oxidase (laccase) domain
273 287 COG1513 P Cyanate lyase
750 826 COG1528 P Ferritin
571 748 COG1613 P ABC-type sulfate transport system, periplasmic component
985 9674 COG1629 P Outer membrane receptor protein, Fe transport
619 1027 COG1633 P Rubrerythrin, includes spore coat protein YhjR
1088 1535 COG1652 P Cytoplasmic potassium-binding protein Kbp/XkdP/YgaU, contains LysM domain
935 1207 COG1668 C P ABC-type Na+ efflux pump, permease component NatB
977 1498 COG1773 P Flavorubredoxin
707 890 COG1785 P R Alkaline phosphatase
814 1014 COG1814 P Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family
108 190 COG1824 P Permease, similar to cation transporters
907 1130 COG1863 P Multisubunit Na+/H+ antiporter, MnhE subunit
501 622 COG1910 P Periplasmic molybdate-binding protein/domain
1117 1789 COG1914 P Mn2+ or Fe2+ transporter, NRAMP family
1315 2159 COG1918 P Fe2+ transport protein FeoA
245 253 COG1930 P ABC-type cobalt transport system, periplasmic component
331 333 COG1965 P Fe-S cluster assembly protein CyaY, frataxin homolog
584 791 COG1971 P Putative Mn2+ efflux pump MntP
586 642 COG2032 P Cu/Zn superoxide dismutase
514 576 COG2046 P ATP sulfurylase (sulfate adenylyltransferase)
1086 2053 COG2059 P Chromate transport protein ChrA
683 727 COG2060 P K+-transporting ATPase, KdpA subunit
849 2549 COG2072 P Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD
864 1271 COG2111 P Multisubunit Na+/H+ antiporter, MnhB subunit
793 1105 COG2116 P Formate/nitrite transporter FocA, FNT family
1139 2924 COG2128 P Alkylhydroperoxidase family enzyme, contains CxxC motif
1173 2497 COG2132 D M P Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)
1271 2834 COG2146 P Q Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase
689 725 COG2156 P K+-transporting ATPase, KdpC subunit
391 433 COG2180 O C P Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor
525 662 COG2181 C P Nitrate reductase gamma subunit
919 1293 COG2193 P Bacterioferritin (cytochrome b1)
857 1037 COG2212 P Multisubunit Na+/H+ antiporter, MnhF subunit
386 476 COG2215 P ABC-type nickel/cobalt efflux system, permease component RcnA
676 720 COG2216 P K+ transport ATPase, ATPase subunit KdpB
2132 6722 COG2217 P Cation-transporting P-type ATPase
469 1049 COG2221 P Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits
1213 2289 COG2223 P Nitrate/nitrite transporter NarK
1719 2390 COG2239 P Mg/Co/Ni transporter MgtE (contains CBS domain)
1047 1580 COG2346 P Truncated hemoglobin YjbI
534 785 COG2372 P Copper-binding protein CopC (methionine-rich)
525 999 COG2375 P NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains
663 1365 COG2382 P Enterochelin esterase or related enzyme
145 154 COG2403 P Zn/Ni/Co-binding GTPase YjiA, predicted metallochaperone, CobW/Nha3/YciC family
1799 3862 COG2608 P Copper chaperone CopZ
371 1657 COG2710 H P Nitrogenase Mo-Fe protein NifD/coenzyme F430 biosynthesis subunit CfbD
680 1019 COG2807 P Cyanate permease
266 319 COG2822 P Iron uptake system EfeUOB, periplasmic (or lipoprotein) component EfeO/EfeM
628 890 COG2837 P Periplasmic deferrochelatase/peroxidase EfeB
747 974 COG2847 P Copper(I)-binding protein
1177 1320 COG2860 P Trimeric intracellular cation channel, TRIC family
1026 1160 COG2895 P Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family
1369 2422 COG2897 P 3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains
201 217 COG2899 P Uncharacterized TerC-related membrane protein, DUF475 domain
750 1018 COG2906 P Bacterioferritin-associated ferredoxin
538 543 COG2924 O P Fe-S cluster biosynthesis and repair protein YggX
758 760 COG2967 P Uncharacterized conserved protein ApaG affecting Mg2+/Co2+ transport
624 626 COG2981 E P Sulfate transporter CysZ
396 446 COG2998 P ABC-type tungstate transport system, permease component
843 1105 COG3004 C P Na+/H+ antiporter NhaA
450 474 COG3025 P Inorganic triphosphatase YgiF, contains CYTH and CHAD domains
241 254 COG3043 C P Nitrate reductase cytochrome c-type subunit NapB
152 158 COG3067 C P Na+/H+ antiporter NhaB
1017 8373 COG3119 P Arylsulfatase A or related enzyme, AlkP superfamily
604 633 COG3142 P Copper homeostasis protein CutC
631 828 COG3158 P K+ uptake protein Kup
373 417 COG3174 P Membrane component of predicted Mg2+ transport system, contains DUF4010 domain
742 1558 COG3182 P Integral membrane siderophore reductase FoxB, contains PepSY domain
996 2093 COG3221 P ABC-type phosphate/phosphonate transport system, periplasmic component
254 272 COG3230 P Heme oxygenase
504 514 COG3253 H P Coproheme decarboxylase/chlorite dismutase
431 492 COG3256 P Nitric oxide reductase large subunit
528 872 COG3258 P Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain
608 691 COG3263 C P NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains
234 335 COG3301 P Nitrite/polysulfide reductase, membrane component NrfD/PsrC
265 332 COG3303 P Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit
300 330 COG3338 P Carbonic anhydrase
737 1171 COG3350 P Heavy metal-bindng TRASH/YHS domain, predicted Cu/Ag metallochaperone
200 223 COG3376 P High-affinity nickel/cobalt permease
517 861 COG3420 P Nitrous oxide reductase accessory protein NosD, contains tandem CASH domains
120 121 COG3443 P Periplasmic Zn/Cd-binding protein ZinT
315 462 COG3454 P Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM
680 1308 COG3540 P Phosphodiesterase/alkaline phosphatase D
435 619 COG3546 P Mn-containing catalase (includes spore coat protein CotJC)
140 176 COG3615 P Tellurite resistance protein TehB, SAM-dependent methylase, cupin superfamily
268 283 COG3624 P Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG
278 297 COG3625 P Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH
272 291 COG3626 P Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI
270 287 COG3627 P Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase PhnJ
676 922 COG3638 P ABC-type phosphate/phosphonate transport system, ATPase component
680 1386 COG3639 P ABC-type phosphate/phosphonate transport system, permease component
240 351 COG3667 P Uncharacterized conserved protein involved in copper resistance
152 176 COG3684 G P Tagatose-1,6-bisphosphate/sulfofructosephosphate aldolase
338 655 COG3685 P Iron homeostasis protein YciF (ferroxidase)
835 2230 COG3696 P Cu/Ag efflux pump CusA
64 67 COG3700 P R Acid phosphatase, class B
435 552 COG3703 P Gamma-glutamylcyclotransferase ChaC2 (glutathione degradation)
509 2902 COG3712 T P Periplasmic ferric-dicitrate binding protein FecR, regulates iron transport
284 295 COG3720 P Putative heme degradation protein
111 119 COG3721 P Putative heme iron utilization protein
306 476 COG3746 P Phosphate-selective porin
395 580 COG3781 P Predicted membrane chloride channel, bestrophin family
230 258 COG3793 P Tellurite resistance protein TerB
122 132 COG3965 P Predicted Co/Zn/Cd cation transporter, cation efflux family
303 364 COG4097 P Predicted ferric reductase
378 386 COG4100 P R Cystathionine beta-lyase family protein involved in aluminum resistance
474 565 COG4103 P Tellurite/oxyanion resistance protein, TerB superfamily
277 293 COG4107 P ABC-type phosphonate transport system, ATPase component PhnK
185 209 COG4114 P Ferric iron reductase protein FhuF, involved in iron transport
374 447 COG4117 P Thiosulfate reductase cytochrome b subunit
701 751 COG4148 P ABC-type molybdate transport system, ATPase component ModC
1283 1374 COG4149 P ABC-type molybdate transport system, permease component ModB
127 128 COG4150 P ABC-type sulfate transport system, periplasmic component
586 642 COG4208 P ABC-type sulfate transport system, permease component
265 274 COG4263 P Nitrous oxide reductase
286 542 COG4264 P Siderophore synthetase component IucA/IucC/SbnC
181 219 COG4275 P Chromate resistance protein ChrB1
165 243 COG4300 P Cadmium resistance protein CadD, predicted permease
283 411 COG4314 P Nitrous oxide reductase accessory protein NosL
108 124 COG4362 P Nitric oxide synthase, oxygenase domain
205 227 COG4521 P ABC-type taurine transport system, periplasmic component
107 114 COG4525 P ABC-type taurine transport system, ATPase component
351 368 COG4531 P ABC-type Zn2+ transport system, periplasmic component/surface adhesin ZnuA
472 473 COG4535 P Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains
689 698 COG4536 P Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains
388 522 COG4548 P Nitric oxide reductase activation protein
82 82 COG4555 C P ABC-type Na+ transport system, ATPase component NatA
477 510 COG4558 P ABC-type hemin transport system, periplasmic component
247 256 COG4559 P ABC-type hemin transport system, ATPase component
146 181 COG4572 P Cation transport regulator ChaB
90 97 COG4592 P ABC-type Fe2+-enterobactin transport system, periplasmic component
140 180 COG4594 P ABC-type Fe3+-citrate transport system, periplasmic component
326 332 COG4604 P ABC-type enterochelin transport system, ATPase component
332 341 COG4605 P ABC-type enterochelin transport system, permease component
330 338 COG4606 P ABC-type enterochelin transport system, permease component
359 400 COG4607 P ABC-type enterochelin transport system, periplasmic component
209 277 COG4615 P ABC-type siderophore export system, fused ATPase and permease components
221 227 COG4619 P ABC-type iron transporter FetAB, ATPase component
619 1565 COG4638 P R Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit
663 794 COG4651 P Predicted Kef-type K+ transport protein, K+/H+ antiporter domain
380 388 COG4662 P ABC-type tungstate transport system, periplasmic component
45 48 COG4693 P Oxidoreductase (NAD-binding), involved in siderophore biosynthesis
982 8454 COG4771 P Outer membrane receptor for ferrienterochelin and colicins
417 607 COG4772 P Outer membrane receptor for Fe3+-dicitrate
545 1493 COG4773 P Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid
571 1250 COG4774 P Outer membrane receptor for monomeric catechols
276 292 COG4778 P Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL
305 502 COG4779 P ABC-type enterobactin transport system, permease component
21 25 COG4881 P Predicted membrane anchor for polysulfide/nitrite-type reductase, PsrC/NrfD syperfamily
158 158 COG4985 P ABC-type phosphate transport system, auxiliary component PstA
210 219 COG4986 P ABC-type anion transport system, duplicated permease component
402 472 COG5013 C P Nitrate reductase alpha subunit
73 74 COG5036 U P SPX domain-containing protein involved in vacuolar polyphosphate accumulation
40 87 COG5386 P Heme-binding NEAT domain
114 115 COG5446 P Putative cobalt transporter membrane subunit CbtA
143 185 COG5455 P Periplasmic regulator RcnB of Ni and Co efflux
272 275 COG5456 P Nitrogen fixation protein FixH
162 201 COG5478 P Low affinity Fe/Cu permease
315 531 COG5569 P Periplasmic Cu and Ag efflux protein CusF
67 67 COG5612 P Ni/Co/Cd-binding protein CnrX (heavy-metal resistance)
158 163 COG5615 P Membrane protein involved in copper transport
353 431 COG5646 O P Iron-binding protein Fra/YdhG, frataxin family (Fe-S cluster biosynthesis)