DataSet Record GDS1239: Expression Profiles Data Analysis Tools Sample Subsets
Title: Inflammatory lung injury and effect of simvastatin
Cluster AnalysisGDS1239 Cluster Image
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Summary: Analysis of effect of simvastatin in LPS-induced inflammatory model of acute lung injury. Male C57BL/6J administered simvastatin 24 hours prior to and concomitant with LPS. Simvastatin is a 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitor that mediates endothelial cell barrier protection.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Jacobson JR, Barnard JW, Grigoryev DN, Ma SF et al. Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury. Am J Physiol Lung Cell Mol Physiol 2005 Jun;288(6):L1026-32. PMID: 15665042
Reference Series: GSE1871 Sample count: 12
Value type: count Series published: 2004/10/26